Advanced Personalized Therapeutics and Precision Surgery Program in Childhood Cancers

The Advanced Personalized Therapeutics and Precision Surgery (ATPTS) Program in Childhood Cancers is “next-level” precision medicine. The program is redefining pediatric cancer care by tailoring medical treatment to the specific vulnerabilities in a child’s tumor, such as genes or proteins. By profiling tumors, we are not only identifying genetic targets but discovering newer, more effective personalized therapies.
The program is structured around three aims:
- A precision medicine clinic to identify genetic vulnerabilities
- A precision approach to surgery that informs decision-making during the surgical procedure
- A research program to identify new targets for cell therapy in pediatric cancers
The ATPTS Program will expand the number of children benefiting from precision medicine and increase the number of therapeutic options available to patients.
How we serve you
The ATPTS Program brings together CHOP experts in developmental therapeutics, rare tumors, genomic diagnostics, health informatics, neurosurgery and more. This team is determined to create a new era for personalized medicine in cancer care, aimed at saving more children with cancer while maximizing their quality of life.
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Cancer Center -
Center for Diagnostic Innovation -
Brain Tumor Program -
Developmental Therapeutics Program -
Leukemia and Lymphoma Program -
Immunotherapy Program -
Neurosurgery -
Oncology Psychosocial Services Program -
Precision Medicine for High-Risk Pediatric Cancer -
Relapsed Leukemia and Lymphoma Program -
Solid Tumor Program
Conditions we treat
Our program’s current focus is on certain types of cancer.

Why choose us
The APTPS Program builds upon initial research efforts from CHOP’s Center for Precision Medicine for High-risk Pediatric Cancer. We profile children's tumors in-house at CHOP, identify their unique genetic vulnerabilities, and develop new therapies for those children through clinical trials.

Meet our team
The ATPTS Program features one of the most accomplished teams of childhood cancer experts in the world.

Our research
We strive to make discoveries that address the current lack of drugs that are needed to target the diversity of tumors seen in pediatric patients.
Give to the Cancer Center
There are many ways to support CHOP's Cancer Center. A gift of any size can help us make life-changing breakthroughs and advance our work for children everywhere.
