Childhood Obesity Publications

These obesity-related publications were authored by investigators associated with the Healthy Weight Program.

2014

Bailey LC, Forrest CB, Zhang P, Richards TM, Livshits A, DeRusso PA: Association of Antibiotics in Infancy with Early Childhood Obesity. JAMA Pediatrics Online November 2014 Notes: Online September 29, 2014.

Bout-Tabaku S, Klieger SB, Wrotniak BH, Sherry DD, Zemel BS, Stettler N. Adolescent obesity, joint pain, and hypermobility. Pediatr Rheumatol Online J. 2014 Mar 29;12(1):11. doi: 10.1186/1546-0096-12-11.

Parks EP, Zemel B, Moore RH, Berkowitz RI. Change in body composition during a weight loss trial in obese adolescents. Pediatr Obes. 2014 Feb;9(1):26-35. doi: 10.1111/j.2047-6310.2012.00139.x. Epub 2013 Feb 5.

Forrest CB, Margolis P, Seid M, Colletti RB. PEDSnet: How A Prototype Pediatric Learning Health System Is Being Expanded Into A National Network. Health Aff (Millwood). 2014;33(7):1171–1177. doi:10.1377/hlthaff.2014.0127.

Weber DR, Leonard MB, Shults J, Zemel B. A Comparison of Fat and Lean Body Mass Index to BMI for the Identification of Metabolic Syndrome in Children and Adolescents. J Clin Endocrinol Metab. 2014 Jun 13:jc20141684.

2013

Xi D, Roizen J, Lai M, Gandhi N, Kublaoui B. Paraventricular nucleus Sim1 neuron ablation mediated obesity is resistant to high fat diet. PLoS One. 2013 Nov 19;8(11):e81087. doi: 10.1371/journal.pone.0081087. eCollection 2013.

Berkowitz RI, Rukstalis MR, Bishop-Gilyard CT, Moore RH, Gehrman CA, Xanthopoulos MS, Cochran WJ, Louden D, Wadden TA. Treatment of adolescent obesity comparing self-guided and group lifestyle modification programs: a potential model for primary care. J Pediatr Psychol. 2013 Oct; 38(9):978-86.  Epub2013 Jun 8.

Hill DL, Parks EP, Zemel BS, Shults J, Stallings VA, Stettler N. Resting energy expenditure and adiposity accretion among children with Down syndrome: a 3-year prospective study. Eur J Clin Nutr. 2013 Oct;67(10):1087-91. doi: 10.1038/ejcn.2013.137. Epub 2013 Jul 31.

Sarwer DB, Moore RH, Diewald LK, Chittams J, Berkowitz RI, Vetter M, Volger S, Wadden TA; POWER-UP Research Group. The impact of a primary care-based weight loss intervention on the quality of life. Int J Obes (Lond). 2013 Aug;37 Suppl 1:S25-30. doi: 10.1038/ijo.2013.93.

Tsai AG, Wadden TA, Volger S, Sarwer DB, Vetter M, Kumanyika S, Berkowitz RI, Diewald LK, Perez J, Lavenberg J, Panigrahi ER, Glick HA. Cost-effectiveness of a primary care intervention to treat obesity. Int J Obes (Lond). 2013 Aug;37 Suppl 1:S31-7. doi: 10.1038/ijo.2013.94.

Volger S, Wadden TA, Sarwer DB, Moore RH, Chittams J, Diewald LK, Panigrahi E, Berkowitz RI, Schmitz K, Vetter ML; POWER-UP Research Group. Changes in eating, physical activity and related behaviors in a primary care-based weight loss intervention. Int J Obes (Lond). 2013 Aug;37 Suppl 1:S12-8. doi: 10.1038/ijo.2013.91.

Wadden TA, Volger S, Tsai AG, Sarwer DB, Berkowitz RI, Diewald LK, Carvajal R, Moran CH, Vetter M; POWER-UP Research Group. Managing obesity in primary care practice: an overview with perspective from the POWER-UP study. Int J Obes (Lond). 2013 Aug;37 Suppl 1:S3-11. doi: 10.1038/ijo.2013.90. Review.

Xanthopoulos MS, Moore RH, Wadden TA, Bishop-Gilyard CT, Gehrman CA, Berkowitz RI. The association between weight loss in caregivers and adolescents in a treatment trial of adolescents with obesity. J Pediatr Psychol. 2013 Aug; 38(7):766-74. Epub 2013 Apr 28.

Yuan H, Schwab RJ, Kim C, He J, Shults J, Bradford R, Huang J, Marcus CL. Relationship between body fat distribution and upper airway dynamic function during sleep in adolescents. Sleep. 2013 Aug 1;36(8):1199-207. doi: 10.5665/sleep.2886.

Abrams P, Levitt Katz LE, Moore RH, Xanthopoulos MS, Bishop-Gilyard CT, Wadden TA, Berkowitz RI. Threshold for improvement in insulin sensitivity with adolescent weight loss. J Pediatr. 2013 Sep;163(3):785-90. doi: 10.1016/j.jpeds.2013.04.003. Epub 2013 May 22.

Bailey LC, Milov DE, Kelleher K, Kahn MG, Del Beccaro M, Yu F, Richards T, Forrest CB. Multi-Institutional Sharing of Electronic Health Record Data to Assess Childhood Obesity. PLoS One. 2013 Jun; 8(6):e66192

Deliard S, Panossian S, Mentch FD, Kim CE, Hou C, Frackelton EC, Bradfield JP, Glessner JT, Zhang H, Wang K, Sleiman PM, Chiavacci RM, Berkowitz RI, Hakonarson H, Zhao J, Grant SF. The missense variation landscape of FTO, MC4R, and TMEM18 in obese children of African Ancestry. Obesity (Silver Springs). 2013 Jan; 21(1):159-63.

Forrest CB, Bevans KB, Riley AW, Crespo R, Louis TA. Health and School Outcomes During Children's Transition Into Adolescence. J Adolesc Health. 2013;52(2):186–194. doi:10.1016/j.jadohealth.2012.06.019.

Koren D, Marcus CL, Kim C, Gallagher PR, Schwab R, Bradford RM, Zemel BS. Anthropometric predictors of visceral adiposity in normal-weight and obese adolescents. Pediatr Diabetes. 2013.

Weber DR, Moore RH, Leonard MB, Zemel BS. Fat and lean BMI reference curves in children and adolescents and their utility in identifying excess adiposity compared with BMI and percentage body fat. Am J Clin Nutr. 2013;98(1):49-56. PMCID: 3683820.

Yau G, Schluchter M, Taylor HG, et al. Bullying of extremely low birth weight children: associated risk factors during adolescence. Early Hum Dev. 2013;89(5):333–338. doi:10.1016/j.earlhumdev.2012.11.004.

2012

Yuan H, Pinto SJ, Huang J, McDonough JM, Ward MB, Lee YN, Bradford RM, Gallagher PR, Shults J, Konstantinopoulou S, Samuel JM, Katz ES, Hua S, Tapia IE, Marcus CL. Ventilatory responses to hypercapnia during wakefulness and sleep in obese adolescents with and without obstructive sleep apnea syndrome. Sleep. 2012 Sep 1;35(9):1257-67. doi: 10.5665/sleep.2082.

Foster GD, Shantz KL, Vander Veur SS, Oliver TL, Lent MR, Virus A, Szapary PO, Rader DJ, Zemel BS, Gilden-Tsai A. A randomized trial of the effects of an almond-enriched hypocaloric diet in the treatment of obesity. Am J Clin Nutr. 2012 Aug;96(2):249-54. doi: 10.3945/ajcn.112.037895. Epub 2012 Jun 27.

Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PM, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, St Pourcain B, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, van der Valk RJ, de Jongste JC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein MT, Lindgren CM, Mägi R, Boreham CA, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen AL, Li M, Raitakari O, Lehtimäki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AI, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Møller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O'Rahilly S, Meirhaeghe A, Sørensen TI, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin MR, Jaddoe VW, Smith GD, Hakonarson H, Grant SF; Early Growth Genetics Consortium. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012 May; 44(5):526-31.

Zemel B. Are urban Chinese infants gaining too much weight? Am J Hum Biol. 2012 Sep-Oct;24(5):585-6. doi: 10.1002/ajhb.22293. Epub 2012 May 24.

Xi D, Gandhi N, Lai M, Kublaoui BM. Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure. PLoS One. 2012;7(4):e36453. doi: 10.1371/journal.pone.0036453. Epub 2012 Apr 27.

Leibowitz KL, Moore RH, Ahima RS, Stunkard AJ, Stallings VA, Berkowitz RI, Chittams JL, Faith MS, Stettler N. Maternal obesity associated with inflammation in their children. World J Pediatr. 2012 Feb;8(1):76-9. Epub 2011 Aug 27.

Grant SF, Glessner JT, Bradfield JP, Zhao J, Tirone JE, Berkowitz RI, Hakonarson H, Sondheimer N. Lack of relationship between mitochondrial heteroplasmy or variation and childhood obesity. Int J Obes (Lond). 2012 Jan;36(1):80-3. doi: 10.1038/ijo.2011.206. Epub 2011 Oct 18.

2011

Berkowitz RI, Fabricatore AN. Obesity, psychiatric status, and psychiatric medications. Psychiatr Clin North Am. 2011 Dec;34(4):747-64. Epub 2011 Oct 19.

Wadden TA, Wilson Gt, Stunkard AJ, Berkowitz RI. Preface. Obesity and associated eating disorders: a guide for mental health professionals. Psychiatr Clin North Am. 2011 Dec;34(4):xiii-xvi.

Zhao J, Bradfield JP, Zhang H, Sleiman PM, Kim CE, Glessner JT, Deliard S, Thomas KA, Frackelton EC, Li M, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF. Role of BMI-associated loci identified in GWAS meta-analyses in the context of common childhood obesity in European Americans. Obesity (Silver Spring). 2011 Dec;19(12):2436-9. Epub 2011 Jul 21.

Florin TA, Shults J, Stettler N. Perception of overweight is associated with poor academic performance in US adolescents. J Sch Health. 2011 Nov;81(11):663-70. doi: 10.1111/j.1746-1561.2011.00642.x.

Wadden TA, Volger S, Sarwer DB, Vetter ML, Tsai AG, Berkowitz RI, Kumanyika S, Schmitz KH, Diewald LK, Barg R, Chittams J, Moore RH. A two-year randomized trial of obesity treatment in primary care practice. N Engl J Med. 2011 Nov 24;365(21):1969-79. Epub 2011 Nov 14.

Koren D, Levitt Katz LE, Brar PC, Gallagher PR, Berkowitz RI, Brooks LJ. Sleep architecture and glucose and insulin homeostasis in obese adolescents. Diabetes Care. 2011 Nov;34(11):2442-7. Epub 2011 Sep 20.

Berkowitz RI, Wadden TA, Gehrman CA, Bishop-Gilyard CT, Moore RH, Womble LG, Cronquist JL, Trumpikas NL, Levitt Katz LE, Xanthopoulos MS. Meal replacements in the treatment of adolescent obesity: a randomized controlled trial. Obesity (Silver Spring). 2011 Jun;19(6):1193-9. Epub 2010 Dec 9.

Zhao J, Bradfield JP, Li M, Zhang H, Mentch FD, Wang K, Sleiman PM, Kim CE, Glessner JT, Frackelton EC, Chiavacci RM, Berkowitz RI, Zemel BS, Hakonarson H, Grant SF. BMD-associated variation at the Osterix locus is correlated with childhood obesity in females. Obesity (Silver Spring). 2011 Jun;19(6):1311-4. doi: 10.1038/oby.2010.324. Epub 2011 Jan 6.

Bishop-Gilyard CT, Berkowitz RI, Wadden TA, Gehrman CA, Cronquist JL, Moore RH. Weight reduction in obese adolescents with and without binge eating. Obesity (Silver Spring). 2011 May;19(5):982-7. Epub 2010 Oct 14.

Bevans KB, Sanchez B, Teneralli R, Forrest CB. Children's eating behavior: the importance of nutrition standards for foods in schools. J Sch Health. 2011;81(7):424–429. doi:10.1111/j.1746-1561.2011.00611.x.

Faulconbridge LF, Wadden TA, Berkowitz RI, Pulcini ME, Treadwell T. Treatment of Comorbid Obesity and Major Depressive Disorder: A Prospective Pilot Study for their Combined Treatment. J Obes. 2011;2011:870385. Epub 2011 May 22.

Forrest CB, Bevans KB, Riley AW, Crespo R, Louis TA. School outcomes of children with special health care needs. Pediatrics. 2011;128(2):303–312. doi:10.1542/peds.2010-3347.

2010

Kral TV, Moore RH, Stunkard AJ, Berkowitz RI, Stettler N, Stallings VA, Tanaka LM, Kabay AC, Faith MS. Adolescent eating in the absence of hunger and relation to discretionary calorie allowance. J Am Diet Assoc. 2010 Dec;110(12):1896-900

Glessner JT, Bradfield JP, Wang K, Takahashi N, Zhang H, Sleiman PM, Mentch FD, Kim CE, Hou C, Thomas KA, Garris ML, Deliard S, Frackelton EC, Otieno FG, Zhao J, Chiavacci RM, Li M, Buxbaum JD, Berkowitz RI, Hakonarson H, Grant SF. A genome-wide study reveals copy number variants exclusive to childhood obesity cases. Am J Hum Genet. 2010 Nov 12;87(5):661-6. Epub 2010 Oct 14.

Denburg MR, Pradhan M, Shults J, Jones A, Palmer JA, Baluarte HJ, Leonard MB. Longitudinal relations between obesity and hypertension following pediatric renal transplantation. Pediatr Nephrol. 2010 Oct;25(10):2129-39. doi: 10.1007/s00467-010-1572-4. Epub 2010 Jun 22.

Hope AA, Kumanyika SK, Shults J, Holmes WC. Changes in Health-Related Quality of Life among African-Americans in a lifestyle weight loss program. Qual Life Res. 2010 Sep;19(7):1025-33. doi: 10.1007/s11136-010-9669-6. Epub 2010 May 11.

Foster GD, Wyatt HR, Hill JO, Makris AP, Rosenbaum DL, Brill C, Stein RI, Mohammed BS, Miller B, Rader DJ, Zemel B, Wadden TA, Tenhave T, Newcomb CW, Klein S. Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial. Ann Intern Med. 2010 Aug 3;153(3):147-57. doi: 10.7326/0003-4819-153-3-201008030-00005.

Kim RJ, Shah R, Tershakovec AM, Zemel BS, Sutton LN, Grimberg A, Moshang T. Energy expenditure in obesity associated with craniopharyngioma. Childs Nerv Syst. 2010 Jul;26(7):913-7. doi: 10.1007/s00381-009-1078-1. Epub 2010 Jan 27.

Zhao J, Li M, Bradfield JP, Zhang H, Mentch FD, Wang K, Sleiman PM, Kim CE, Glessner JT, Hou C, Keating BJ, Thomas KA, Garris ML, Deliard S, Frackelton EC, Otieno FG, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. BMC Med Genet. 2010 Jun 14;11:96.

Tolson KP, Gemelli T, Gautron L, Elmquist JK, Zinn AR, Kublaoui BM. Postnatal Sim1 deficiency causes hyperphagic obesity and reduced Mc4r and oxytocin expression. J Neurosci. 2010 Mar 10;30(10):3803-12. doi: 10.1523/JNEUROSCI.5444-09.2010.

Berkowitz RI, Moore RH, Faith MS, Stallings VA, Kral TV, Stunkard AJ. Identification of an obese eating style in 4-year-old children born at high and low risk for obesity. Obesity (Silver Spring). 2010 Mar;18(3):505-12. Epub 2009 Sep 24.

Zhao J, Bradfield JP, Zhang H, Annaiah K, Wang K, Kim CE, Glessner JT, Frackelton EC, Otieno FG, Doran J, Thomas KA, Garris M, Hou C, Chiavacci RM, Li M, Berkowitz RI, Hakonarson H, Grant SF. Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI. Diabetes. 2010 Mar;59(3):751-5. Epub 2009 Nov 23.

Allison DB, Elobeid MA, Cope MB, Brock DW, Faith MS, Van der Veur S, Berkowitz R, Cutter G, McVie T, Gadde KM, Foster GD. Sample Size in Obesity Trials: Patient Perspective versus Current Practice. Medical Decision Making. 2010 Jan-Feb:30(1):68-75. Epub 2009 Aug 12. PMC2914621

Bevans KB, Fitzpatrick L-A, Sanchez BM, Riley AW, Forrest C. Physical education resources, class management, and student physical activity levels: a structure-process-outcome approach to evaluating physical education effectiveness. J Sch Health. 2010;80(12):573–580. doi:10.1111/j.1746-1561.2010.00544.x.

Butryn ML, Wadden TA, Rukstalis MR, Bishop-Gilyard C, Xanthopoulos MS, Louden D, Berkowitz RI. Maintenance of weight loss in adolescents: current status and future directions. J Obes. 2010;2010:789280. Epub 2011 Jan 2.

2009

Kral TV, Stunkard AJ, Berkowitz RI, Stettler N, Stallings VA, Kabay A, Faith MS. Energy density at a buffet-style lunch differs for adolescents born at high and low risk of obesity. Eat Behav. 2009 Dec;10(4):209-14. Epub 2009 Jul 15.

Zhao J, Bradfield JP, Li M, Wang K, Zhang H, Kim CE, Annaiah K, Glessner JT, Thomas K, Garris M, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF. The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity (Silver Spring). 2009 Dec;17(12):2254-7. Epub 2009 May 28.

Hildebrandt MA, Hoffmann C, Sherrill-Mix SA, Keilbaugh SA, Hamady M, Chen YY, Knight R, Ahima RS, Bushman F, Wu GD. High-fat diet determines the composition of the murine gut microbiome independently of obesity. Gastroenterology. 2009 Nov;137(5):1716-24.e1-2. doi: 10.1053/j.gastro.2009.08.042. Epub 2009 Aug 23.

Kumanyika SK, Wadden TA, Shults J, Fassbender JE, Brown SD, Bowman MA, Brake V, West W, Frazier J, Whitt-Glover MC, Kallan MJ, Desnouee E, Wu X. Trial of family and friend support for weight loss in African American adults. Arch Intern Med. 2009 Oct 26;169(19):1795-804. doi: 10.1001/archinternmed.2009.337.

Reese PP, Feldman HI, Asch DA, Thomasson A, Shults J, Bloom RD. Short-term outcomes for obese live kidney donors and their recipients. Transplantation. 2009 Sep 15;88(5):662-71. doi: 10.1097/TP.0b013e3181b27a17.

Grant SF, Bradfield JP, Zhang H, Wang K, Kim CE, Annaiah K, Santa E, Glessner JT, Thomas K, Garris M, Frackelton EC, Otieno FG, Shaner JL, Smith RM, Imielinski M, Chiavacci RM, Li M, Berkowitz RI, Hakonarson H. Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry. Obesity (Silver Spring). 2009 Jul;17(7):1461-5. Epub 2009 Mar 5.

Faulconbridge LF, Wadden TA, Berkowitz RI, Sarwer DB, Womble LG, Hesson LA, Stunkard AJ, Fabricatore AN. Changes in symptoms of depression with weight loss: results of a randomized trial. Obesity (Silver Spring). 2009 May;17(5):1009-16. Epub 2009 Feb 5.

Leibowitz KL, Moore RH, Stunkard AJ, Stallings VA, Berkowitz RI, Stettler N, Chittams JL, Faith MS. Cardiovascular disease risk factor (CVDRF) associated waist circumference patterns in obese-prone children. Int J Pediatr Obes. 2009;4(3):150-9.

Shah S, Kublaoui BM, Oden JD, White PC. (2009) Screening for Type 2 Diabetes In Obese Youth. Pediatrics, 124(2):573-9