Complex Vascular Anomalies Program Research

Research Studies and Clinical Trials

The CVAP was designed and implemented in response to the need for a well-coordinated multi-disciplinary clinic and research program. This allows providers to collaborate more effectively in serving patients and their families.

The research component revolves around our findings that certain genetic mutations are the root cause of many vascular anomalies, some of which are responsive to advanced therapies that are not yet clinically indicated treatments for these conditions. Conducting clinical trials to help find promising treatments for patients with vascular anomalies will hopefully lead to U.S. Food and Drug Administration approval of these much-needed treatments. As a result, in the future countless more patients will benefit from this life-saving precision medicine approach pioneered at CHOP.

Surveillance Epidemiology of Coronavirus (COVID-19) Under Research Exclusion

The SECURE-VA registry was created to capture important information about pediatric and adult COVID-19 cases that are occurring across the world in patients living with vascular anomalies. The goal of this voluntary reporting system is to better understand outcomes of COVID-19 cases in this population of patients.

Access the registry.