Lymphatic Research and Publications

Physicians and researchers from The Children’s Hospital of Philadelphia are actively involved in lymphatic research. Review some of our research publications for more information about the work our team is involved in.

Lymphatic interventions

Biko DM, Smith CL, Otero HJ, Saul D, White AM, DeWitt A, Glatz AC, Piccoli DA, Mamula P, Rome JJ, Dori Y. Intrahepatic dynamic contrast MR lymphangiography: initial experience with a new technique for the assessment of liver lymphatics. Eur Radiol. 2019 Oct;29(10):5190-5196. PMID: PMID

Li D, March ME, Gutierrez-Uzquiza A, Kao C, Seiler C, Pinto E, Matsuoka LS, Battig MR, Bhoj EJ, Wenger TL, Tian L, Robinson N, Wang T, Liu Y, Weinstein BM, Swift M, Jung HM, Kaminski CN, Chiavacci R, Perkins JA, Levine MA, Sleiman PMA, Hicks PJ, Strausbaugh JT, Belasco JB, Dori Y, Hakonarson H. ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor. Nat Med. 2019 Jul;25(7):1116-1122. PMID: 31263281

Biko DM, DeWitt AG, Pinto EM, Morrison RE, Johnstone JA, Griffis H, O'Byrne ML, Fogel MA, Harris MA, Partington SL, Whitehead KK, Saul D, Goldberg DJ, Rychik J, Glatz AC, Gillespie MJ, Rome JJ, Dori Y. MRI Evaluation of Lymphatic Abnormalities in the Neck and Thorax after Fontan Surgery: Relationship with Outcome. Radiology. 2019 Jun;291(3):774-780. PMID: 30938628

Weissler JM, Cho EH, Koltz PF, Carney MJ, Itkin M, Laje P, Levin LS, Dori Y, Kanchwala SK, Kovach SJ. Lymphovenous Anastomosis for the Treatment of Chylothorax in Infants: A Novel Microsurgical Approach to a Devastating Problem. Plast Reconstr Surg. 2018 Jun;141(6):1502-1507. PMID: 29794709

Biko DM, Reisen B, Otero HJ, Ravishankar C, Victoria T, Glatz AC, Rome JJ, Dori Y. Imaging of central lymphatic abnormalities in Noonan syndrome. Pediatr Radiol. 2019 May;49(5):586-592. PMID: 30613845

Giacalone G, Yamamoto T, Belva F, Hayashi A, Dori Y, Zviman MM, Gysen M, Nam HH, Jolley MA, Kato M. The Application of Virtual Reality for Preoperative Planning of Lymphovenous Anastomosis in a Patient with a Complex Lymphatic Malformation. J Clin Med. 2019 Mar 15;8(3). pii: E371. PMID: 30884770

Maxim G. Itkin, Francis X. McCormack and Yoav Dori. Diagnosis and Treatment of Lymphatic Plastic Bronchitis in Adults Using Advanced Lymphatic Imaging and Percutaneous Embolization. Ann Am Thorac Soc. 2016 Oct;13(10):1689-1696. PMID: 27599255

Dori Y, Keller MS, Rome JJ, Gillespie MJ, Glatz AC, Dodds K, Goldberg DJ, Goldfarb S, Rychik J, Itkin M. Percutaneous Lymphatic Embolization of Abnormal Pulmonary Lymphatic Flow as Treatment of Plastic Bronchitis in Patients With Congenital Heart Disease. Circulation. 2016 Mar 22;133(12):1160-70. PMID: 26864093

Dori Y, Keller MS, Rychik J, Itkin M. Successful treatment of plastic bronchitis by selective lymphatic embolization in a Fontan patient. Pediatrics. 2014 Aug;134(2):e590-5. PMID: 25002668

Dori Y, Zviman MM, Itkin M. Dynamic contrast-enhanced MR lymphangiography: feasibility study in swine. Radiology. 2014 Nov;273(2):410-6. PMID: 24988434

Dori Y, Keller MS, Fogel MA, Rome JJ, Whitehead KK, Harris MA, Itkin M. MRI of lymphatic abnormalities after functional single-ventricle palliation surgery. AJR Am J Roentgenol. 2014 Aug;203(2):426-31. PMID: 24848564