Pediatric Multiple Sclerosis and Neuroinflammatory Disorders Clinic Clinical Studies

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Progressive Degeneration in Pediatric MS

The purpose of this research study is to learn more about childhood demyelination, why demyelination occurs and to better understand how demyelination affects children and adolescents.  To do this, we need to ask detailed questions about a child's early life, environment, and physical activity. To understand how demyelination affects the brain we will obtain special pictures of the brain, called magnetic resonance images (MRI). We will carefully assess all children and adolescents, not only at the time of demyelination, but also once yearly for 2 additional years.

In childhood MS, we wish to learn about quality of life, diet, and physical activity. MRI pictures of the brain and analysis of blood samples will help us also to better understand disease activity. IRB 15-012130

Visual Measures in Pediatric MS

The purpose of this research study is to determine methods that will better determine whether someone has MS and to develop ways to measure the disease. These tests will help doctors learn about vision and how the brain processes information from your eyes in people with MS and healthy people. You will be asked to spend the day at CHOP to complete vision testing and other study procedures. Please contact Amy Lavery (; 267-425-2136) if you are interested!