Does the Mutation of Coronavirus Affect the Capacity of Vaccines to Prevent Disease?

In this short video, Dr. Hank Bernstein talks about SARS-CoV-2 variants and vaccine immunity.

Transcript

Does the Mutation of Coronavirus Affect the Capacity of Vaccines to Prevent Disease?

Hank Bernstein, MD: I'm Hank Bernstein and I'm speaking on behalf of the Vaccine Education Center at Children's Hospital of Philadelphia. The question, “Does the mutation of the coronavirus affect the capacity of vaccines to prevent disease?” The answer is, possibly. That is one of the major concerns that we have, and I know that people have heard about the different variants around the world, actually. We know that there's a variant in the UK. We know there's one in South Africa. We know there's one in Brazil. And there's variants within the United States.

These are concerns because this means that the circulating SARS-CoV-2 virus is different in some way than the strain that's been incorporated into the current COVID-19 vaccines. This makes it difficult to say for sure how much immunity will be developed with the current vaccines as they've been made. So, we'll need to stay tune to see whether booster doses are required or a change in the vaccine itself will be necessary going forward.

Related Centers and Programs: Vaccine Education Center

Last Reviewed on Mar 16, 2021