In patients with systemic juvenile idiopathic arthritis (sJIA), it is often difficult for physicians to distinguish between infection and inflammatory disease activity. The purpose of this study is to see if two biomarkers, called CP and PCT, can help physicians identify when patients have an infection versus a flare of their sJIA. This study involves two study visits, one at the time of a sJIA flare and one approximately 60 days after. We will ask participants to provide 3 teaspoons of blood for laboratory assessments, as well as answer brief questionnaires about their disease. The researchers will also review each participant's medical records for information regarding the history of their disease.
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