Congenital Hyperinsulinism is the most common cause of low
blood sugar (hypoglycemia) in infants and children.  Infants who are born with this problem have
low blood sugar, which can cause seizures or brain damage. 

We are doing this study to see if the patterns of
abnormalities in controlling insulin in children and adults with
hyperinsulinism are related to any underlying genetic cause and to identify
possible new genetic causes.  This will
be done by standard clinical tests of insulin control: a glucose tolerance
test, a protein tolerance test, and a fasting test.

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