Autism Spectrum Disorder Clinical Studies

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MRI Study for Prediction of ASD

Thisstudy seeks to understand the key differences and similarities in braindevelopment between infants whose siblings do and do not have autism. Participantswill be asked to make 3 visits to CHOP over time to complete cognitive andbehavioral testing and a non-invasive MRI. Participants will be compensated fortheir time and receive a written feedback report.

Vocal Biomarkers of Autism Spectrum Disorder

The goal of this study is to identify unique characteristics in the way kids and teens with Autism Spectrum Disorder (ASD) speak in comparison to typically developing peers. We are looking to partner with children and adolescents ages 6-17 with a confirmed diagnosis of autism spectrum disorder and typically developing children and adolescents. In response to the COVID-19 pandemic, all study activities

may be completed from home. Participants will be asked to complete questionnaires, as well as weekly language-based activities 7 times. You will receive compensation for your participation. Upon request, you will receive a clinical report detailing assessment results. 

Brain Imaging Study of Minimally-Verbal/Nonverbal Children with Autism Spectrum Disorder and Children with Developmental/Intellectual Disability

The Lurie Family Foundations MEG Imaging Lab at CHOP are looking for minimally/nonverbal children with ASD and those with an intellectual or developmental delay without ASD who may or may not be minimally/nonverbal for a study on how the brain works. We are looking for both male and female children between the ages of 8-12 years old and infants 4 to 18 months of age. The study involves two visits to CHOP. The first visit can last up to 2 to 5 hours (depending on Cohort group) and will involve neuropsychological/developmental testing. The second visit can last up to 2-3 hours depending on Cohort group and will consist of an MEG brain imaging scan. We will provide you with reimbursement for your time and parking. For more information please contact our study coordinator at 267-426-4914 or

MEG Autism Study

The Lurie Family Foundations MEG Imaging Lab at CHOP are looking for Healthy Children and those with an Autism Spectrum Disorder for a study on how the brain works. We are looking for both male and female children between the ages of 6-12 years old. We will provide you with reimbursement for your time and parking will be at no cost. For more information please contact our study coordinator by emailing

SPARK: Simons Foundation Powering Autism Research for Knowledge

The mission of SPARK is to ignite research at an unprecedented scale to improve lives by advancing our understanding of autism. To join this national autism research cohort, individuals with a professional diagnosis of autism and their biological family members will be asked to share information about their medical and family history, as well as provide a DNA sample. Please contact the Center for Autism Research for more information at 1-866-570-6524 or

Comorbidity of Autism and Epilepsy

Dr. William Gaetz. has partnered with pediatric neurologist, Dr. Eric Marsh and neuropsychologist, Dr. Lisa Blaskey to better understand Epilepsy in children who have an Autism Spectrum Disorder (ASD). This study will use a non-invasive brain scanning technology as well as cognitive testing results to understand brain differences in children with Autism and Epilepsy. We hope that the information we get from this study will help children in the future who have ASD. For this research to be successful we need to work with male children with a diagnosis of ASD or ASD and Epilepsy who are 8 to 17 years of age. Families will be reimbursed for their time and have an opportunity to discus their child's cognitive testing results with our neuropsychologist post testing. Please contact our study staff at for more information.

What Do You Eat? An Online Study for Youth with ASD

The goal of this research study is to develop an online questionnaire about what youth with Autism Spectrum Disorder (ASD) eat and how it impacts their daily lives. Youth (7-16 years) and their parent will complete a questionnaire about food and eating habits online. Parents will complete an additional child background and medical history questionnaire online. Participants will be paid for their time with an Amazon online gift card.

Social Coordination

The purpose of this study is to understand how motor function- the way we move our faces and bodies- impactssocial communication. We are seeking adolescents ages 12-17 with or without ASD or a mixed psychological diagnosis (ADD, ADHD, ODD, or anxiety).  To accommodate COVID protective measures, most of the study tasks can be completed from home through video-based assessment and online questionnaires. Then, families will be asked to make one or two short visits to the Roberts Center. During this visit you will play games and talk with our research staff. All participants will also receive a full psychological work-up, including behavioral testing for ADHD, anxiety, autism, and mood disorders. Participants and their parents are paid for their time completing the virtual visit as well as for time spent completing questionnaires. Each participant also receives a full psychological report and  personalized feedback with recommendations.

Autism ETA Cohort Study

Parents and their child between 16 and 21 on the autism spectrum are both asked to partner with us for this study as we learn more about the decisions you make about transportation, including driving. We also hope to learn about how transportation influences quality of life and other outcomes. First, parents will answer questions about themselves and their child. Then, both parents and their child will complete up to six surveys over the course of two years. The surveys will ask about your thoughts and experiences with transportation and driving, quality of life, relationships, and other outcomes.