Andrew J. Bauer, MD

Andrew J. Bauer, MD

Andrew J. Bauer, MD, is an endocrinologist and Medical Director of the Pediatric Thyroid Center at Children's Hospital of Philadelphia.

Areas of Expertise: Acquired hypothyroidism (Hashimoto's thyroidism), Autonomously functioning nodules, Congenital hypothyroidism, DICER1-PPB familial tumor predisposition syndrome, Familial thyroid cancer, Follicular thyroid cancer, Hyperthyroidism (Graves' disease), Inherited syndromes associated with increased risk of thyroid nodules and thyroid cancer, Multiple endocrine neoplasia, Papillary thyroid cancer, Pediatric thyroid disease, PTEN hamartoma syndrome, Thyroid hormone resistance, Thyroid nodules, Thyroid transport defects, Thyroid cancer
Locations: Main Campus; Specialty Care & Surgery Center, Voorhees
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

Dr. Bauer is a native of Buffalo, NY. He completed his undergraduate at Canisius College and his medical degree at the State University of New York at Buffalo School of Medicine. He completed his pediatric training at Madigan Army Medical Center, Fort Lewis, Tacoma, WA, and his pediatric endocrine training at the National Capital Consortium, Uniformed Services University, Bethesda, MD. In 2013, Dr. Bauer retired from the United States Army after 29 years of service, to include two combat tours in Iraq.

Dr. Bauer's clinical and research area of interests are focused on the study of pediatric thyroid disease, including hypothyroidism, hyperthyroidism, thyroid nodular disease, thyroid cancer, and familial thyroid tumor syndromes. Within this field, Dr. Bauer has published more than 70 manuscripts, chapters and reviews and is a regularly invited lecturer and visiting professor at national and international meetings and academic institutes.

Dr. Bauer maintains active membership in the Endocrine Society, the Pediatric Endocrine Society, and the American Thyroid Association (ATA). In the ATA, Dr. Bauer served on the thyroid hormone replacement committee and as co-chair of the guidelines on the evaluation and management of pediatric thyroid nodules and differentiated thyroid cancer. Dr. Bauer is a member on the ATA Board of Directors and, most recently, was invited to serve on the World Health Organization, IARC Section of Environment and Radiation, international expert group charged to create guidelines on thyroid screening after nuclear disasters.

Dr. Bauer is an Associate Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. He serves as the Director of the Thyroid Center at Children's Hospital of Philadelphia, a multidisciplinary center organized to provide coordinated and comprehensive care for children and adolescents with thyroid disorders.

Education and Training

Medical School

MD - State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY

Internship

Pediatrics - Madigan Army Medical Center, Tacoma, WA

Residency

Pediatrics - Madigan Army Medical Center, Tacoma, WA

Fellowship

Pediatric Endocrinology - National Capital Consortium, Uniformed Services University, Bethesda, MD

Board Certification

General Pediatrics
Pediatric Endocrinology

Titles and Academic Titles

Medical Director, Pediatric Thyroid Center

Endocrinologist

Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Publications

Papers

2018

Kilberg MJ, Rasooly IR, LaFranchi SH, Bauer AJ, Hawkes CP. Newborn Screening in the US May Miss Mild Persistent Hypothyroidism. Journal of Pediatrics. 2017 Dec;(192):204-08. doi.org/10.1016/j.jpeds.2018.09.003 [Epub ahead of print]

2015

Rutter MM, Jha P, Schultz KA, Sheil A, Harris AK, Bauer AJ, Field AL, Geller J, Hill DA. DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association. J Clin Endocrinol Metab. 2015 Nov 10:jc20152169. [Epub ahead of print]

Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM, Dinauer CA, Hamilton J, Hay ID, Luster M, Parisi MT, Rachmiel M, Thompson GB, Yamashita S; American Thyroid Association Guidelines Task Force. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2015 Jul;25(7):716-59. doi: 10.1089/thy.2014.0460.

Kovatch KJ1, Bauer AJ, Isaacoff EJ, Prickett KK, Adzick NS, Kazahaya K, Sullivan LM, Mostoufi-Moab S. Pediatric Thyroid Carcinoma in Patients with Graves' Disease: The Role of Ultrasound in Selecting Patients for Definitive Therapy. Horm Res Paediatr. 2015 Apr 15. [Epub ahead of print]

2014

Jonklaas J1, Bianco AC, Bauer AJ, Burman KD, Cappola AR, Celi FS, Cooper DS, Kim BW, Peeters RP, Rosenthal MS, Sawka AM. Guidelines for the treatment of hypothyroidism: prepared by the American Thyroid Association task force on thyroid hormone replacement. Thyroid. 2014 Dec;24(12):1670-751. doi: 10.1089/thy.2014.0028.

Yeh MW1, Bauer AJ, Bernet VA, Ferris RL, Loevner LA, Mandel SJ, Orloff LA, Randolph GW, Steward DL. American Thyroid Association Statement on Preoperative Imaging for Thyroid Cancer Surgery. Thyroid. 2014 Sep 29. [Epub ahead of print]

2012

Klubo-Gwiezdzinska J, Jensen K, Bauer A, Patel A, Costello J, Burman K, et al. The expression of translocator protein in human thyroid cancer and its role in the response of thyroid cancer cells to oxidative stress. JJ Endocrinol. Epub 2012 May 29. Cited in PubMed; PMID 22645299. Read the abstract

Pinsker JE, McBayne K, Edwards M, Jensen K, Crudo DF, Bauer AJ. Transient hypothyroidism in premature infants after short term topical iodine exposure: an avoidable risk? Pediatrics and Neonatology 2012; 53 (3), May-June.

Klubo-Gwiezdzinska J, Jensen K, Costello J, Patel A, Hoperia V, Bauer A, et al. Metformin inhibits growth and decreases resistance to anoikis in medullary thyroid cancer cells. Endocr Relat Cancer. Endocr Relat Cancer. 2012 May 24;19(3):447-56. Print 2012 Jun. Cited in PubMed; PMID 22389381. Read the abstract

2011

Bauer AJ, Francis GL. Molecular Signature of Differentiated Thyroid Cancer: New Discoveries, New Opportunities. Expert Review of Endocrinology and Metabolism. 2011 Nov.

Patel A, Klubo-Gwiezdzinska J, Hoperia V, Larin A, Jensen K, Bauer A, et al. BRAF (V600E) mutation analysis from May-Grunwald Giemsa-stained cytological samples as an adjunct in identification of high-risk papillary thyroid carcinoma. Endocr Pathol. 2011 Dec;22(4):195-9. Cited in PubMed; PMID 21948220. Read the abstract

Jensen K, Costello J, Klubo-Gwiezdzinska J, Patel A, Bauer A, Vasko V. Inhibition of gap junctional transfer confers anoikis susceptibility to thyroid cancer cells. Endocr Relat Cancer, 2011 Sep 20;18(5):613-26. Cited in PubMed; PMID 21813730. Read the abstract

Bauer AJ. Approach to the pediatric patient with Graves' disease: when is definitive therapy warranted? J Clin Endocrinol Metab. 2011 Mar;96(3):580-8. Cited in PubMed; PMID 21378220. Read the article

2010

Hoperia V, Larin A, Jensen K, Bauer A, Vasko V. Thyr0id fine needle aspiration biopsies in children: study of cytological-histological and immunostaining with anti-thyroid peroxidase monoclonal antibodies (MoAb47). Int J Pediatr Endocrinol. 2010;2010:690108. Epub 2010 Jun 21. Cited in PubMed; PMID 20652042. Read the article

Jensen K, Patel A, Larin A, Hoperia V, Saji M, Bauer A, et al. Human herpes simplex viruses in benign and malignant thyroid tumors. J Pathol. 2010 Jun;221(2):193-200. Cited in PubMed; PMID 20455254. Read the abstract

Jensen K, Patel A, Hoperia V, Larin A, Bauer A, Vasko V. Dynamic changes in E-Cadherin gene promoter methylation during metastatic progression in papillary thyroid cancer. Experimental and Therapeutic Medicine, 2010 May-June; 1(3):457-462.

Almeida MQ, Muchow M, Boikos S, Bauer AJ, Griffin KJ, Tsang KM, et al. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. Hum Mol Genet. 2010 Apr 15;19(8):1387-98. Epub 2010 Jan 15. Cited in PubMed; PMID 20080939. Read the article

Abstracts

2012

Percival C, Larson N, Bauer AJ. Avoiding unnecessary thyroid procedures: recognizing ectopic thymic tissue in pediatric patients [abstract]. The 2012 Pediatric Endocrine Society Annual Meeting; 2012 Apr 26-27; Boston, MA.

2011

Jensen K, Patel A, Bauer A, Vasko V. HSV2 infection targets thyroid gland and affects expression of DNA repair molecules in thyroid cells [abstract]. ENCO 2011: 93rd Annual Meeting and Expo; 2011 Jun 4-7; Boston, MA.

2010

Almeida M, Bauer AJ, Stratakis CA. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically-induced skin papillomas by dysregulation of the cell cycle and Wnt signaling [abstract]. ENDO 2010: 92nd Annual Meeting and Expo; 2010 Jun 19-22; San Diego, CA.

Books

Chapters

2014

Doros L, Schultz KA, Stewart DR, Bauer AJ, Williams G, Rossi CT, Carr A, Yang J, Dehner LP, Messinger Y, Hill DA. In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH, Stephens K, editors. DICER1-Related Disorders. GeneReviews®[Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.

2012

Stratakis C, Pacak K, Pinsker J, Bauer AJ. Endocrine related cancer. In: Sarafoglou K, Hoffman G, Roth K, editors. Pediatric endocrinology and inborn errors of metabolism. 2nd ed. McGraw-Hill; 2012.

Bauer AJ. Clinical behavior and genetics of non-syndromic familial non-medullary thyroid cancer. In: Stratakis CA, editor. Genetic endocrine tumor syndrome. Frontiers in Hormone Research. Karger, Basal; 2012

Waguespack S, Bauer AJ. Follicular thyroid cancer in children and adolescents. In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 3rd ed. Totowa (NJ): Humana Press; 2012.

Bauer AJ. Thyroid nodules in children and adolescents. In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 3rd ed. Totowa (NJ): Humana Press; 2012.

Mostoufi-Moab S, Bauer AJ. Differentiated thyroid cancer in children and adolescents. In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 3rd ed. Totowa (NJ): Humana Press; 2012.

Bauer AJ, Francis GL. Molecular aspects of thyroid cancer in children and adolescents.  In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 3rd ed. Totowa (NJ): Humana Press; 2012.

2011

Gannon A, Lessig M, Bauer AJ. Papillary thyroid cancer in children and adolescents. In: Clinical Decision Support: Pediatrics. Decision Support in Medicine, LLC; 2011

Lessig M, Gannon A, Bauer AJ. Medullary Thyroid Carcinoma. In: Clinical Decision Support: Pediatrics. Decision Support in Medicine, LLC; 2011

Philla K, Bauer AJ. Acquired hypothyroidism in children and adolescents. In: Clinical Decision Support: Pediatrics. Decision Support in Medicine, LLC; 2011

Alter CA, Rossi WC, Bauer AJ. Goiter. In: Zorc JJ, editor. Schwartz’s clinical handbook of pediatrics. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2011.

Bauer AJ, Waguespack S, Grover A, Francis GL. Thyroid neoplasia. In: Radovick S, MacGillivray M, editors. Pediatric endocrinology: a practical clinical guide. 2nd ed. Totowa (NJ): Humana Press; 2011.

2010

Waguespack S, Bauer AJ, Huh, Ying AK. Endocrine tumors. In: Pizzo PA, Poplack DG. Principles and practice of pediatric oncology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2010.

2009

Bauer AJ, Tuttle RM, Francis GL. Thyroid cancer, children and adolescents. In: Van Nostrand D, Loom G, Wartofsky L, Washington Hospital Center, editors. Thyroid cancer: a guide for patients. 2nd ed. Baltimore: Keystone Press; 2009.

2007

Bauer AJ, Pinsker J, Pacak K, Stratakis CA. Endocrine related cancer. In: Sarafoglou K, editor. Pediatric endocrinology and inborn errors of metabolism. McGraw-Hill 2007.

2006

Ribeiro RC, Rodriquez-Galindon C, Zambetti GP, Figueiredo BC, Pacak K,, Bauer AJ, Stratakis CA. Rare pediatric endocrine tumors. In: Raghavan D, Brecher ML, Johnson DH, Meropol NJ, Moots P, Rose P, editors. Textbook of uncommon cancers. 3rd ed. West Sussex, England: Wiley and Sons; 2006.

Kemmer T, Bauer AJ, Yu C, Lynch J. Malnutrition in humanitarian crises. In: Lynch J, Burman S, editors.  Helping the children. Disaster preparedness project. American Academy of Pediatrics; 2006.

2005

Bauer AJ. Follicular thyroid cancer; special aspects in children and adolescents. In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 2nd ed. Totowa (NJ): Humana Press; 2005.

Bauer AJ, Poth M. Papillary thyroid cancer: special aspects in children. In: Wartofsky L, editor. Thyroid cancer: a clinical guide. 2nd ed. Totowa (NJ): Humana Press; 2005.

2004

Bauer AJ, Tuttle RM, Francis GL. Thyroid cancer and thyroid cancer in children and adolescents. In: Pescovitz OH, Eugster EA, editors. Pediatric endocrinology: mechanisms, manifestations, and management. Philadelphia: Lippincott Williams & Wilkins; 2004.

2002

Bauer AJ, Tuttle RM, Francis GL. Differentiated thyroid carcinoma in children. The Endocrinologist, 12: 135-42, 2002.

2001

Bauer AJ, Francis GL, Poth M. Review of precocious puberty, part III. Premature thelarche and adrenarche. The Endocrinologist,11: 196-203, 2001.

Posters and Presentations

2012

Recupero A, Costello J, Patel A, Bauer AJ, Vasko V. The antidiabetic drug Metformin inhibits cell growth and induces anoikis in a MTC cell line [oral presentation]. The 2012 Pediatric Endocrine Society Annual Meeting; 2012 Apr 26-27; Boston, MA.

2010

Jensen K, Costello J, Patel A, Bauer A, Vasko V. Anoikis in thyroid cancer cells [poster]. International Thyroid Congress; 2010 Sep 11-16; Paris, France.

Jensen K, Hoperia V, Larin A, Bauer A, Vasko V. Thyroid FNAB’s in children: a study of cytological-histological correlation and the utility of MoAb47 immunostaining as malignancy marker [oral presentation]. 44th Annual AAP Uniformed Services Pediatric Seminar; 2010 Mar 7-10; San Diego, CA. 

Editorial and Academic Positions

Editorial positions

Editorial board

Journal of Thyroid Disorders and Therapy (OMICS publishing)
Frontiers in Genomic Endocrinology

Reviewer

Journal of Clinical Endocrinology and Metabolism
Thyroid
Clinical Cancer Research
International Journal of Pediatric Endocrinology
Hormone Research in Pediatrics
Thyroid Research
Endocrine
Journal of Pediatrics
Cancer Investigation
Archives of Pediatrics & Adolescent Medicine
Journal of Translational Medicine
Hormones and Cancer

Institutional and academic committees

2012-present, Task Force, Pre-operative Staging Guidelines, Surgical Affairs Committee, The American Thyroid Association

2012-present, Task Force, Thyroid Hormone Replacement Guidelines Committee

2012-present, Spring 2012 American Thyroid Association Thyroid Hormone Replacement Symposium Organization Committee

2009-present, Task Force, Pediatric Thyroid Cancer Guideline Committee, The American Thyroid Association