Jeffrey Bergelson, MD

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Dr. Bergelson is an attending physician in the Division of Infectious Diseases  at Children's Hospital of Philadelphia. He holds the Stanley Plotkin Endowed Chair in Pediatric Infectious Diseases.

Areas of Expertise: Enterovirus entry into cells, Management and treatment of common pediatric infectious diseases, Viral pathogenesis, Virus receptors, Cell biology of virus entry
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - University of Pennsylvania School of Medicine, Philadelphia, PA


Pediatrics - University of California, San Francisco, CA


Pediatrics - University of California, San Francisco, CA


Infectious Diseases - Children's Hospital, Boston, MA
Research Fellow in Medicine - Dana-Farber Cancer Institute, Boston, MA

Board Certification


Titles and Academic Titles

Attending Physician, Division of Infectious Diseases

Stanley Plotkin Endowed Chair in Pediatric Infectious Diseases

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Professor of Microbiology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

How viruses enter cells to begin infection




Pinkert S, Röger C, Kurreck J, Bergelson JM, Fechner H.: The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection. J Virol.  90: 5601-10, 2016.

Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Desarmenien MG, Valero J, Bernex F, Henaff D, Bayo-Puxan N, Chen J-W, Lonjon N, De Koninck Y, Malva J, Bergelson JM, Di Luca M, Schiavo G, Salinas S, Kremer E.  : Coxsackievirus adenovirus receptor loss impairs adult neurogenesis, synapse content and hippocampus plasticity. The Journal of Neuroscience 36: 9558-71, 2016.


Harris KG, Morosky SA, Drummond CG, Patel M, Kim C, Stolz DB, Bergelson JM, Cherry S, Coyne CB. RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells. Cell host & microbe. 2015; 18(2):221-32. NIHMSID: NIHMS715934

Pan J, Zhang L, Odenwald MA, Shen L, Turner JR, Bergelson JM. Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. Journal of virology. 2015; 89(8):4311-8.

Pan J, Zhang L, Organtini LJ, Hafenstein S, Bergelson JM. Specificity of coxsackievirus B3 interaction with human, but not murine, decay-accelerating factor: replacement of a single residue within short consensus repeat 2 prevents virus attachment. Journal of virology. 2015; 89(2):1324-8.


Kim C, Bergelson JM. Echovirus 7 entry into polarized caco-2 intestinal epithelial cells involves core components of the autophagy machinery. Journal of virology. 2014; 88(1):434-43.


Krieger SE, Kim C, Zhang L, Marjomaki V, Bergelson JM. Echovirus 1 entry into polarized Caco-2 cells depends on dynamin, cholesterol, and cellular factors associated with macropinocytosis. Journal of virology. 2013; 87(16):8884-95.

Nishimura Y, Lee H, Hafenstein S, Kataoka C, Wakita T, et al. Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction. PLoS pathogens. 2013; 9(7):e1003511.

Bergelson JM, Coyne CB. Picornavirus entry. Advances in experimental medicine and biology. 2013; 790:24-41.


Yoder JD, Cifuente JO, Pan J, Bergelson JM, Hafenstein S: The crystal structure of a coxsackievirus B3-RD variant, and a refined 9Å cryoEM reconstruction of the virus complexed with decay accelerating factor (DAF), provide a new footprint of DAF onto the virus surface. J Virol 86: 1257-81, 2012.

Kim C, Bergelson JM: Echovirus 7 entry into polarized intestinal epithelial cells requires clathrin and Rab7. MBio 3: e00304-11, April 2012.


Pan J, Narayanan B, Shah S, Yoder JD, Cifuente JO, Hafenstein S, Bergelson JM: Single amino acid changes in the virus capsid permit coxsackievirus B3 to bind decay-accelerating factor. J Virol 85(14): 7436-43, July 2011.

Bozym RA, Patel K, White C, Cheung KH, Bergelson JM, Morosky SA, Coyne CB: Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells. Mol Biol Cell 22(17): 3010-21, July 2011.


Pichla-Gollon SL, Lin S-W, Hensley SE, Losaro MO, Herkenhoff-Haut L, Drinker M, Tatsis N, Gao G-P, Wilson JM, Ertl HCJ, Bergelson JM: Effect of preexisting immunity on an adenovirus vaccine vector: in vitro neutralization assays fail to predict inhibition by antiviral antibody in vivo. J. Virology 83(11), 2009.

Patel KP, Coyne CB, Bergelson JM: Dynamin- and lipid raft-dependent entry of DAF-binding and non-DAF-binding Coxsackieviruses into non-polarized cells. Journal of virology Aug 2009.

Kallewaard Nicole L, Zhang Lili, Chen Jin-Wen, Guttenberg Marta, Sanchez Melissa D, Bergelson Jeffrey M: Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis. Cell host & microbe 6(1): 91-8, Jul 2009.


Pichla-Gollon, Susan L.  Drinker, Mark.  Zhou, Xiangyang.  Xue, Feng.  Rux, John J.  Gao, Guang-Ping.  Wilson, James M.  Ertl, Hildegund C J.  Burnett, Roger M.  Bergelson, Jeffrey M.: Structure-based identification of a major neutralizing site in an adenovirus hexon. Journal of Virology 81: 1680-9, 2007

Coyne CB, Shen L, Turner JR, Bergelson JM  : Coxsackievirus entry from epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5   Cell Host & Microbe 2: 181-192, 2007.

Coyne CB, Kim KS, Bergelson JM.: Poliovirus entry into human brain microvascular endothelial cells requires receptor-induced activation of the tyrosine phosphatase SHP-2. EMBO Journal 26: 4016-4028, 2007.


Maginnis, Melissa S.  Forrest, J Craig.  Kopecky-Bromberg, Sarah A.  Dickeson, S Kent.  Santoro, Samuel A.  Zutter, Mary M.  Nemerow, Glen R.  Bergelson, Jeffrey M.  Dermody, Terence S.: Beta1 integrin mediates internalization of mammalian reovirus. Journal of Virology 80: 2760-70, 2006.

Coyne CB, Bergelson JM: Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell 124: 119-131, 2006.

Chen, Jin-Wen.  Zhou, Bin.  Yu, Qian-Chun.  Shin, Sangyoon J.  Jiao, Kai.  Schneider, Michael D.  Baldwin, H Scott.  Bergelson, Jeffrey M.: Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves. Circulation Research 98: 923-30, 2006.


Milstone AM, Petrella JE, Sanchez MD, Mahmud M, Whitbeck JC, Bergelson JM: Interaction with coxsackievirus and adenovirus receptor (CAR), but not with decay accelerating factor (DAF), induces A particle formation in a DAF-binding coxsackievirus B3 isolate. J. Virol 79: 655-660, 2005.

Harvala H, Kalimo H, Bergelson J, Stanway G. and Hyypia T: Tissue tropism of recombinant coxsackieviruses in an adult mouse model. J. Gen. Virol. 86: 1897-907, 2005.


Stonebraker, Jaclyn R.  Wagner, Danielle.  Lefensty, Robert W.  Burns, Kimberlie.  Gendler, Sandra J.  Bergelson, Jeffrey M.  Boucher, Richard C.  O'Neal, Wanda K.  Pickles, Raymond J.: Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection. Journal of Virology 78: 13755-68, 2004.

Coyne CB, Voelcker T, Pichla SL, Bergelson JM: The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction. J. Biol. Chem 279: 48079-48084, 2004.


Varnavski, Andrei N.  Schlienger, Katia.  Bergelson, Jeffrey M.  Gao, Guang-Ping.  Wilson, James M.: Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector. Human Gene Therapy 14: 533-44, 2003.

Shim, K S.  Bergelson, J M.  Furuse, M.  Ovod, V.  Krude, T.  Lubec, G.: Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down syndrome brain. Journal of Neural Transmission. Supplementum(67), 117-28, 2003.

Chen, Jin-Wen.  Ghosh, Ruma.  Finberg, Robert W.  Bergelson, Jeffrey M.: Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor gene. DNA & Cell Biology 22: 253-9, 2003.

Bilbao, R.  Reay, D P.  Hughes, T.  Biermann, V.  Volpers, C.  Goldberg, L.  Bergelson, J.  Kochanek, S.  Clemens, P R.: Fetal muscle gene transfer is not enhanced by an RGD capsid modification to high-capacity adenoviral vectors. Gene Therapy 10: 1821-9, 2003.


Zeimet AG, Muller-Holzner E, Schuler A, Hartung G, Berger J, Hermann M, Widschwendter M, Bergelson JM, Marth C: Determination of molecules regulating gene delivery using adenoviral vectors in ovarian carcinomas. Gene Ther. 9: 1093-1100, 2002.

Xiang Z-Q, Gao G, Reyes-Sandoval A, Cohen CJ, Li Y, Bergelson JM, Wilson JM, Ertl HCJ: Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. J Virol.  76: 2667-2675, 2002.

Tan K, Zelus BD, Meijers R, Liu J-H, Bergelson JM, Duke N, Zhang R, Joachimiak A, Holmes KV, Wang J-H: Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. EMBO J.  21: 2076-2086, 2002.

Shieh JT, Bergelson JM: Interaction with decay accelerating factor (DAF) facilitates coxsackievirus B infection of polarized epithelial cells. J. Virol.  76: 9474-9480, 2002.

Petrella JE, Cohen CJ, Gaetz J, Bergelson JM: A zebrafish coxsackievirus and adenovirus receptor homologue interacts with coxsackie B virus and adenovirus. J. Virol.  76: 10503-10506, 2002.

Cohen CJ, Xiang ZQ, Gao G-P, Ertl HCJ, Wilson JM, Bergelson JM: Chimpanzee adenovirus CV68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor (CAR). J. Gen. Virol.  83: 151-155, 2002.

Ciarlet M, Crawford SE, Cheng E, Blutt SE, Rice DA, Bergelson JM, Estes MK: VLA-2 (a2b1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J. Virology  76: 1109-1123, 2002.

Chen Z, Ahonen M, Hamalainen H, Bergelson JM, Kahari VM, Lahesmaa R: High-efficiency gene transfer to primary T lymphocytes by recombinant adenovirus vectors. J Immunol Methods  260: 79-89, 2002.

Bernal RM, Sharma S, Gardner BK, Douglas JT, Bergelson JM, Dubinett SM, Batra RK: Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu. Clin Cancer Res  8: 1915-1923, 2002.

Aquilina A, Korda M, Bergelson JM, Humphries M.J, Farndale R, Tuckwell DS: A novel gain of function mutation of the integrin a2 VWFA domain. Eur. J. Biochem.  269: 1136-1144, 2002.


Tan PK, Michou A-I, Bergelson JM, Cotten M: Defining CAR as a cellular receptor for the avian adenovirus CELO using a genetic analysis of the two viral fiber proteins. J. General Virol. 82: 1465-1472, 2001.

Okegawa T, Pong R-C, Li Y, Bergelson JM, Sagalowsky AI, Tsong J-T: Mechanism of the growth inhibitory effect of the coxsackie and adenovirus receptor (CAR) on human bladder cancer: a functional analysis of CAR protein structure. Cancer Research  61: 6592-6600, 2001.

Ohman T, King SL, Krithivas A, Cunningham JC, Dickeson SK, Santoro SA, Bergelson JM: Echoviruses 1 and 8 are genetically closely related, and bind to similar determinants within the VLA-2 I domain. Virus Research  76: 1-8, 2001

Noutsias M, Fechner H, de Jonge H, Wang X, Dekkers D, Houtsmuller AB, Pauschinger M, Bergelson JM, Warraich R, Yacoub M, Hetzer R, Lamers J, Schultheiss H-P, Poller W: Human coxsackie-adenovirus-receptor is colocalized with integrins avb3 and avb5 on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy. Circulation  104: 275-280, 2001.

Cripe TP Dunphy EJ, Holub AD, Saini A, Vasi NH, Mahller YY, Collins MH, Snyder JD, Krasnykh V, Curiel DT, Wickham TJ,  DeGregori J, Bergelson JM, Currier MA: Fiber knob modifications overcome low, heterogeneous expression of the coxsackie-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Research  61: 2953-2960, 2001.

Cohen CJ, Shieh JT-C, Pickles RJ, T Okegawa T, Hsieh J-T, Bergelson JM: The coxsackievirus and adenovirus receptor (CAR) is a transmembrane component of the tight junction. Proc. Natl. Acad. Sci. USA  98: 15192-15196, 2001.

Cohen CJ, Gaetz J, Ohman T, Bergelson JM: Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting. J. Biol. Chem.   276: 25392-25398, 2001.


van Raaij MJ, Chouin E, van der Zandt H, Bergelson JM, Cusack S.  : Dimeric structure of the coxsackievirus and adenovirus receptor at 1.7 Å resolution. Structure  8: 1147-1155, 2000.

Soudais C, Boutin S, Hong SS, Chillon M, Danos O, Bergelson JM, Boulanger P, Kremer EJ: Canine adenovirus type 2 attachment and internalization: coxsackievirus-adenovirus receptor, alternative receptors, and an RGD-independent pathway. J. Virol.  74: 10639-10649, 2000.

Pickles RJ, Fahrner J, Petrella J, Boucher RC, Bergelson JM: Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer. Virology   74: 6050-6057, 2000.

Okegawa T, Li Y, Pong R-C, Bergelson JM, Zhou J, Hsieh J-T: The dual impact of coxsackie and adenovirus receptor expression on human prostate cancer gene therapy. Cancer Research  60: 5031-5036, 2000.

Martino TA, Petric M, Weingartl H, Bergelson JM, Opavsky MA, Richardson CD, Modlin JF, Finberg RW, Kain KC, Willis N, Gauntt CJ, Liu PP: The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus. Virology 271: 99-108, 2000.

Fechner H, Wang X, Wang H, Jansen A, Pauschinger M, Scherubl H, Bergelson JM, Schultheiss HP, Poller W: Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells. Gene Therapy  7: 1954-1968, 2000.


Wang X and Bergelson JM.  : The CAR cytoplasmic and transmembrane domains are not required for infection by coxsackie B viruses and adenoviruses. J. Virology  73: 2559-2562, 1999.

Walters RW, Grunst T, Bergelson JM, Finberg RW, Welsh MW, Zabner J: Basolateral localization of fiber receptors limits adenovirus infection of airway epithelia. J. Biol. Chem.  274: 10219-10226, 1999.

Schachtner SK, Buck CA, Bergelson JM, Baldwin HS: Temporally regulated expression patterns following in utero adenovirus-mediated gene transfer. Gene Therapy  6: 1249-1257, 1999.

Santis G, Legrand V, Hong SS, Davison E, Kirby I, Imler J-L, Finberg RW, Bergelson JM, Mehtali M, Boulanger P: Molecular determinants of adenovirus serotype 5 binding to its cellular receptor CAR. Journal of General Virology  80: 1519-1527, 1999.

Rauma T, Tuukkanen J, Bergelson JM, Davidson BL, Hautala T: Rab5 GTPase regulates recombinant adenovirus endocytosis. J. Virology  73: 9664-9668, 1999.

Li Y, Pong R-C, Hall MC. Tseng C-P, Wang Z, Sagalowsky AI, Bergelson JM, Hsieh JT: Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy. Cancer Research  59: 325-330, 1999.

Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pederson E, Crystal RG: Modification of the genetic program of human alveolar macrophages by adenovirus vectors is feasible, but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. American Journal of Respiratory Cell and Molecular Biology  20: 361-370, 1999.

Hidaka C, Milano E, Leopold PL, Bergelson JM, Hackett NR, Finberg RW, Wickham TJ, Kovesdi I, Roelvink P, Warren RF, Crystal RG: CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in primary human skin fibroblasts. J. Clin. Investigation  103: 579-587, 1999.

Dickeson SK, Mathis NL, Rahman M, Bergelson JM, Santoro SA: Determinants of ligand binding specificity of the a1b1 and a2b2 integrins. J. Biol. Chem.  274: 32182-32191, 1999.


Roelvink PW, Lizonova A, Lee JGM, Li Y, Bergelson JM, Finberg RW, Brough DE, Kovesdi I, Wickham TJ: The coxsackie-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F.  J. Virology  72: 7909-7915, 1998.

Frey BM, Hackett NR, Bergelson JM, Finberg R, Crystal RG, Moore MAS, Rafii S: High-efficiency gene transfer into ex vivo-expanded human hematopoietic progenitors and precursor cells by adenovirus vectors. Blood  91: 2781-2792, 1998.

Filman DJ, Wien MW, Cunningham JA, Bergelson JM, Hogle JM: The structure determination of echovirus 1. Acta Crystallographica D  54: 1261-1272, 1998.

Bergelson JM, Krithivas A, Celi L, Droguett G, Horwitz MS, Wickham T, Crowell RL, Finberg RW: The murine CAR homologue (mCAR) is a receptor for coxsackie B viruses and adenoviruses. J. Virology  72: 415-419, 1998.


King SL, Kamata T, Cunningham JA, Krithivas A, Emsley J, Liddington RC, Takada Y, Bergelson JM: Echovirus 1 interaction with the human very late antigen-2 (integrin a2b1) I domain: identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site. J. Biol. Chem.  272: 28518-28522, 1997.

Emsley J, King SL, Bergelson JM, Liddington RC: Crystal structure of the I-domain from integrin a2b1. J. Biol. Chem.  272: 28512-28517, 1997.

Bergelson JM, Modlin JF, Wieland-Alter W, Cunningham JA, Crowell RL, Finberg RW: Clinical coxsackievirus B isolates differ from laboratory strains in their interaction with two cell surface receptors. Journal of Infectious Diseases  175: 697-700, 1997.

Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krikthivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW: Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science  275: 1320-1323, 1997.


King SL, Cunningham JA, Finberg RW, Bergelson JM: Echovirus 1 interaction with the isolated VLA-2 I domain. J. Virology  69: 3237-3239, 1995.

Bergelson JM, Mohanty J, Crowell RL, St. John NF, Lublin DM, Finberg RW: Coxsackievirus B3 adapted to growth in RD cells binds to decay-accelerating factor (CD55). J. Virology  69: 1903-1906, 1995.


Kawaguchi S, Bergelson JM, Finberg RW, Hemler ME: Integrin a2 cytoplasmic domain deletion effects:  Loss of adhesive activity parallels recruitment into ligand-independent focal adhesions. Molecular Biology of the Cell  5: 977-988, 1994.

Haregewoin A, Solomon K, Hom RC, Soman G, Bergelson JM, Bhan AK, Finberg RW: Cellular expression of a GPI linked T cell activation protein. Cellular Immunology  156: 357-370, 1994.

Edelman JM, Chan, BMC, Uniyal S, Onodera H, Wang DZ, Damjanovich DA, Latzer DA, St. John NF, Finberg RW, Bergelson JM: The mouse VLA-2 homologue supports collagen and laminin adhesion but not virus binding. Cell Adhesion and Communication  2: 131-143, 1994.

Bergelson JM, St. John NF, Kawaguchi S, Pasqualini R, Berdichevsky F, Hemler ME, Finberg RW: The I domain is essential for echovirus 1 interaction with VLA-2. Cell Adhesion and Communication  2: 455-464, 1994.

Bergelson JM, Chan M, Solomon K, St. John NF, Lin H, Finberg RW: Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses. Proc. Natl. Acad. Sci. USA  91: 6245-6248, 1994.


Bergelson JM, St. John N, Kawaguchi S, Chan M, Stubdal H, Modlin J, Finberg RW: Infection by echoviruses 1 and 8 depends on the a2 subunit of human VLA-2. J. Virology  67: 6847-6852, 1993.

Bergelson JM, Chan BMC, Finberg RW, Hemler ME: The integrin VLA-2 binds echovirus 1 and extracellular matrix ligands by different mechanisms. J. Clin. Inv.  92: 232-239, 1993.


Bergelson JM, Shepley MP, Chan BMC, Hemler ME, Finberg RW  : Identification of the integrin VLA-2 as a receptor for echovirus 1. Science 255: 1718-1720, 1992.


Bergelson JM, Shah S, Zaoutis T: Pediatric Infectious Diseases (A Volume in the Pediatric Requisites Series). Mosby, St. Louis, 2008.



Bergelson JM, Coyne CB: Picornavirus entry. Viral Entry Into Host Cells. Stefan Pöhlmann and Graham Simmons (eds.). Landes Bioscience and Springer Science+Business Media, Page: 24-41, 2013.


Dermody TS, Bergelson JM: Biology of viruses. Mechanisms of Microbial Disease. Williams and Wilkins, Baltimorerevised 2011, June 2012.


Bergelson JM, Hanna BD : Myocarditis and pericarditis. Pediatric Infectious Diseases (A Volume in the Pediatric Requisites Series). Mosby, St. Louis, 2008.

Bergelson JM, Dermody TS: Mechanisms of Pediatric viral disease. Pediatric Infectious Diseases (A Volume in the Pediatric Requisites Series). Mosby, St. Louis, 2008.

Bergelson JM: Encephalitis. Pediatric Infectious Diseases (A Volume in the Pediatric Requisites Series). Mosby, St. Louis, 2008.


Bergelson JM: Chapter 7, Central nervous system infections. Blueprints, Pediatric Infectious Diseases. Blackwell, Malden, MA, Page: 38-47, 2004.


Bergelson J: Chapter 22, Other cardiac infections. Pediatric  Infectious Disease Secrets Page: 131-135, 2002 Notes: Hanley & Belfus, Philadelphia.

Bergelson J: Chapter 10, Receptors for coxsackieviruses and echoviruses. Molecular Biology of Picornaviruses Page: 107-113, 2002 Notes: ASM Press, Washington.

Bergelson J: Chapter 38, Infections in the immunocompromised child. Pediatric Infectious Disease Secrets Page: 241-245, 2002 Notes: Hanley & Belfus, Philadelphia.

Finberg R and Bergelson J: Chapter 91, Upper respiratory infections. Saunders Manual of Pediatric Practice Page: 367-371, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J  and Finberg R: Chapter 92, Lower respiratory infections. Saunders Manual of Pediatric Practice Page: 372-375, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 103, Pericarditis. Saunders Manual of Pediatric Practice Page: 399-400, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 102, Myocarditis. Saunders Manual of Pediatric Practice Page: 398-399, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 97, Meningitis. Saunders Manual of Pediatric Practice Page: 387-391, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 101, Endocarditis. Saunders Manual of Pediatric Practice Page: 395-398, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 100, Brain Abscess. Saunders Manual of Pediatric Practice Page: 394-395, 1998 Notes: WB Saunders, Philadelphia, revised 2002.

Bergelson J: Chapter 99, Encephalitis. Saunders Manual of Pediatric Practice Page: 391-393, 1998 Notes: WB Saunders, Philadelphia, revised 2002.


Bergelson J: Review of:  "Cellular receptors for animal Viruses"  Quarterly Review of Biology  ed. E Wimmer (eds.). 71: 119, 1996.


Bergelson J and Finberg R: Regulation of T cell receptor expression: the beginnings of the evidence. The Year in Immunology 3, 1988 Notes: Karger (Basel, Switzerland).


Awards and Honors

2013, Fellow, American Academy of Microbiology
2008, CHOP Residents' Honor Roll for Teaching
1995, Society for Pediatric Research
1995-2000, Established Investigator of the American Heart Association
1998-1991, Fellow of the Leukemia Society
1972, Fellow of the Leukemia Society

Editorial and Academic Positions

Editorial Positions

2015-present, Guest Associate Editor, PLoS Pathogens
2012-present, Faculty of 1000, Pediatric Infectious Diseases
2012-present, Associate Editor, Tissue Barriers
2009-present, Editorial board, Virology
2006-present, Editorial board, Journal of Virology
2004-present, Editorial board, Molecular Medicine

Ad hoc reviewer

British Journal of Cancer
BMC Infectious Diseases
Cancer Gene Therapy
Cancer Investigation
Cancer Research
Cell and Tissue Research
Cell Host and Microbe
Cellular Microbiology
Cell Reports
Chemistry & Biology
Circulation Research
EMBO Journal
Experimental Cell Research
Human Gene Therapy
Journal of Biological Chemistry
Journal of Cell Science
Journal of Clinical Investigation
Journal of Clinical Microbiology
Journal of Gene Medicine
Journal of General Virology
Journal of Infectious Diseases
Journal of Molecular and Cellular Cardiology
Journal of Neuroscience
Journal of Virology
Nature Biotechnology
Nature Communications
Nature Medicine
Nature Structural Biology
Open Virology Journal
Pediatric Emergency Medicine
Pediatric Infectious Diseases Journal
Pediatric Research
PLoS One
PLoS Pathogens
Prostate Cancer
Trends in Cardiovascular Medicine
Trends in Microbiology
Virology Journal
Virus Research

Academic and Institutional Committees

2015-present, Pediatrics Department Committee on Appointments and Promotions
2014-present, Chair, CHOP Institutional Biosafety Committee
1998-present, CHOP Institutional Biosafety Committee

Leadership and Memberships

Memberships in Professional Organizations


2013-present, Scientific Advisory Board, Pasteur Institute, Shanghai


2012-present, American Heart Association
 - 2012-present, Immunology and Microbiology Peer Review Committee
2011-present, American Society for Virology
 - 2011-present, Abstract Review Committee, Annual meeting
2001-present, Pediatric Infectious Diseases Society