Christine E. Boone, MD, PhD
Areas of expertise: Interventional Radiology
Locations: Main Building
About Christine E. Boone, MD, PhD
Titles
Attending Radiologist
Awards and Honors
2025, Roentgen Resident Research Award, Radiological Society of North America (RSNA)
2024, SIO IO Essentials Scholarship Program Travel Award, Society of Interventional Oncology (SIO)
2024, Larry-Stuart Deutsch Scholarship Award, Western Angiographic and Interventional Society (WAIS)
2022, ACR-AUR Research Scholar Program, Association of University Radiologists (AUR) & American College of Radiology (ACR)
2022, Resident and Fellow Grant Recipient, Panacea Financial Foundation
2022, Resident Research Award, Society of Interventional Radiology (SIR)
2022, Summa Cum Laude Award for Scientific Abstract, American Roentgen Ray Society (ARRS)
2021, RSNA Trainee Research Prize, Radiological Society of North America (RSNA)
2018, Medical Student Travel Scholarship, Society of Interventional Radiology (SIR)
2016, 1st Place, Basic Science Oral Presentation, Sleep and Circadian Rhythm Research Day, Johns Hopkins University
2016, Minority Scholars Program Award, American Academy of Neurology (AAN)
2015, Finalist, Medical Student National Election, Young Neurosurgeons Committee, American Association of Neurological Surgeons (AANS)
2014, Simons Foundation Travel Award, Fragile X and Autism-Related Disorders Gordon Research Conference
2012, Turock Young Scientist Award, Johns Hopkins School of Medicine
2009, Cum Laude Graduate & Honoree, Afro-American Cultural Center, Yale University
2008, Yale BioSTEP Program, Yale School of Medicine
2008, Irene and Eric Simon Brain Research Foundation Summer Fellowship Program
2008, Yale College Dean's Fellowship in the Sciences, Yale College Leadership Alliance Summer Research Early Identification Program (SR-EIP)
2006, Undergraduate Summer Research Experience Program, University of Medicine and Dentistry of NJ Graduate School of Biomedical Sciences (UMDNJ-GSBS)
Leadership and Memberships
International
2021-present, Society of Interventional Oncology (SIO)
- 2021-present, Publications Committee
2021-present, Society for Pediatric Interventional Radiology (SPIR)
2020-present, Radiological Society of North America (RSNA)
National
2020-present, American Roentgen Ray Society (ARRS)
2017-present, Society of Interventional Radiology (SIR)
Editorial and Academic Positions
Editorial Positions
2023-present, Reviewer, Journal of Vascular and Interventional Radiology
2021-present, Reviewer, Wiley interdisciplinary reviews, Nanomedicine and nanobiotechnology
2016-present, Reviewer, Journal of Clinical Neuroscience
Education & training
Undergraduate Degree
BS in Molecular, Cellular and Developmental Biology - Yale University, New Haven, CT
Graduate Degree
PhD in Neuroscience - Johns Hopkins University School of Medicine, Baltimore, MD
Medical Degree
MD - Johns Hopkins University School of Medicine, Baltimore, MD
Internship
Transitional Year - Santa Clara Valley Medical Center, Fruitdale, CA
Residency
Resident, T32 IR/DR Clinician-Scientist - University of California San Diego, San Diego, CA
Cardiovascular Imaging Group - University of California San Diego, Department of Radiology, San Diego, CA
Interventional Radiology - University of California San Diego, Department of Radiology, San Diego, CA (Co-Chief Resident)
Fellowship
Pediatric Interventional Radiology - Children's Hospital of Philadelphia, Department of Radiology, Philadelphia, PA
Additional Training
T32 IR/DR Research Year, Bio-nanotechnology Research - University of California San Diego, San Diego, CA
Publications
Publications
2024
Karan, S., Jung, E., Boone, C., & Steinmetz, N. F.: Synergistic combination therapy using cowpea mosaic virus intratumoral immunotherapy and Lag-3 checkpoint blockade. Cancer immunology, immunotherapy: CII 73(3): 51, February 2024 Notes: DOI: 10.1007/s00262-024-03636-2.
Ebrahimi, S., Siddiqui, N., Besser, A., Rodriguez-Soto, A. E., Yu, H., Boone, C., Hsiao, A., Roberts, A. C., Parikh, R., & Rakow-Penner, R.: Application of Differential Subsampling with Cartesian Ordering in Evaluating Left Ovarian Venous Reflux for Pretreatment Planning for Pelvic Venous Disorders. Diagnostics (Basel, Switzerland) 14(16): 1737, August 2024 Notes: DOI: 10.3390/diagnostics14161737.
Omole, A. O., Zhao, Z., Chang-Liao, S., de Oliveira, J. F. A., Boone, C. E., Sutorus, L., Sack, M., Varner, J., Fiering, S. N., & Steinmetz, N. F.: Virus nanotechnology for intratumoural immunotherapy. Nature reviews bioengineering 2(11): 916-929, November 2024 Notes: DOI: 10.1038/s44222-024-00231-z.
2023
Berman, Z. T., Boone, C. E., Melber, D. J., Ballas, J., Parikh, R., Ramos, G., Kelly, T., McHale, M., Picel, A. C., & Roberts, A. C.: Intraoperative Multivessel Embolization Reduces Blood Loss and Transfusion Requirements Compared to Internal Iliac Artery Balloon Placement during Cesarean Hysterectomy for Placenta Accreta Spectrum. Journal of vascular and interventional radiology: JVIR 34(11): 1915-1921, November 2023 Notes: DOI: 10.1016/j.jvir.2023.07.024.
2022
Koellhoffer, E. C., Mao, C., Beiss, V., Wang, L., Fiering, S. N., Boone, C. E., & Steinmetz, N. F.: Inactivated Cowpea Mosaic Virus in Combination with OX40 Agonist Primes Potent Antitumor Immunity in a Bilateral Melanoma Mouse Model. Molecular pharmaceutics 19(2): 592-601, February 2022 Notes: DOI: 10.1021/acs.molpharmaceut.1c00681.
2020
Westbroek, E. M., Pennington, Z., Ahmed, A. K., Xia, Y., Boone, C., Gailloud, P., & Sciubba, D. M: Comparison of complete and near-complete endovascular embolization of hypervascular spine tumors with partial embolization. Journal of neurosurgery. Spine 33(2): 245-251, April 2020 Notes: DOI: 10.3171/2020.1.SPINE191337.
Yan CH, Faraji F, Prajapati DP, Boone CE, DeConde AS.: Association of chemosensory dysfunction and COVID-19 in patients presenting with influenza-like symptoms. International forum of allergy & rhinology 10(7): 806-813, July 2020 Notes: DOI: 10.1002/alr.22579.
Boone, C. E., Wang, C., Lopez-Ramirez, M. A., Beiss, V., Shukla, S., Chariou, P. L., Kupor, D., Rueda, R., Wang, J., & Steinmetz, N. F.: Active Microneedle Administration of Plant Virus Nanoparticles for Cancer in situ Vaccination Improves Immunotherapeutic Efficacy. ACS applied nano materials 3(8): 8037-8051, August 2020 Notes: DOI: 10.1021/acsanm.0c01506.
2019
Boone CE, Koethe Y, Lehrman ED, Kohi MP.: Collateral uterine arterial supply in the setting of various uterine pathologies. Journal of Clinical Interventional Radiology (ISVIR) 2(3): 191-196, September 2018 Notes: DOI: 10.1055/s-0038-1676166.
Goodwin CR, Abu-Bonsrah N, Boone C, Ruiz-Valls A, Sankey EW, Sarabia-Estrada R, Elder BD, Kosztowski T, Sciubba DM.: Non-hepatocellular carcinoma spinal metastases. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia 27: 22-27, May 2019 Notes: DOI: 10.1016/j.jocn.2015.11.003.
Koethe Y, Boone CE, Lehrman ED, Kolli KP, Kumar V, Kohi MP.: Uterine artery embolization as a uterine-sparing solution for postpartum pseudoaneurysms. Journal of Gynecologic Surgery 33(3), June 2019 Notes: DOI: 10.1089/gyn.2019.0023.
2018
Boone, C. E., Davoudi, H., Harrold, J. B., & Foster, D. J.: Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome. Neuroscience 384: 275-289, August 2018 Notes: DOI: 10.1016/j.neuroscience.2018.05.012.
2017
Purvis, T. E., Kessler, R. A., Boone, C., Elder, B. D., Goodwin, C. R., & Sciubba, D. M.: The effect of renal dysfunction on short-term outcomes after lumbar fusion. Clinical neurology and neurosurgery 153: 8-13, February 2017 Notes: DOI: 10.1016/j.clineuro.2016.12.002.
Purvis, T. E., Rodriguez, H. J., Ahmed, A. K., Boone, C., De la Garza-Ramos, R., Elder, B. D., Goodwin, C. R., & Sciubba, D. M.: Impact of smoking on postoperative complications after anterior cervical discectomy and fusion. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia 38: 106-110, April 2017 Notes: DOI: 10.1016/j.jocn.2016.12.044.
Purvis TE, Boone C, Anderson WS.: Development of a Clinically Useful Algorithm for Tractography-Based Ventral Intermediate Nucleus Targeting. Neurosurgery 80(5): N24-N25, May 2017 Notes: DOI: 10.1093/neuros/nyx099.
2016
Boone, C., Caplan, J. M., Garzon-Muvdi, T., Yang, W., Ye, X., Groves, M. L., Tamargo, R. J., Ahn, E. S., & Huang, J.: Hemorrhage Risk in Pediatric Patients with Multiple Intracranial Arteriovenous Malformations. Pediatric neurosurgery 51(4), April 2016 Notes: DOI: 10.1159/000444286.
2015
Boone, C., Salimpour, Y., & Anderson, W. S.: Boo! Fear generalization in the primate amygdala. Neurosurgery 76(6): N11-N12, June 2015 Notes: DOI: 10.1227/01.neu.0000465850.42808.50.
2009
Hagenston, A. M., Rudnick, N. D., Boone, C. E., & Yeckel, M. F.: 2-Aminoethoxydiphenyl-borate (2-APB) increases excitability in pyramidal neurons. Cell calcium 45(3): 310-317, March 2009 Notes: DOI: 10.1016/j.ceca.2008.11.003.
Souayah N, Potian JG, Garcia CC, Krivitskaya N, Boone C, Routh VH, McArdle JJ.: Motor unit number estimate as a predictor of motor dysfunction in an animal model of type 1 diabetes. American journal of physiology. Endocrinology and metabolism 297(3): E602-8, September 2009 Notes: DOI: 10.1152/ajpendo.00245.2009.
Souayah, N., Potian, J. G., Garcia, C. C., Krivitskaya, N., Boone, C., Routh, V. H., & McArdle, J. J.: Motor Unit Number Estimate as a predictor of Motor Dysfunction in an Animal Model of Type I Diabetes. American journal of physiology. Endocrinology and metabolism 297(3): E602-E608, September 2009 Notes: DOI: 10.1152/ajpendo.00245.2009.
Lectures by Invitation
2026
Boone, CE. Invited Discussion Moderator, IR in Immunoengineering Session, Gordon Research Conference on Immunoengineering, Ventura Beach, CA. Feb 2026.
Editorials, Reviews, Chapters
2022
Ormiston, C. K., Padilla, E., Van, D. T., Boone, C., You, S., Roberts, A. C., Hsiao, A., & Taub, P. R.: May-Thurner syndrome in patients with postural orthostatic tachycardia syndrome and Ehlers-Danlos syndrome: a case series. European heart journal. Case reports 6(4): ytac161, April 2022 Notes: DOI: 10.1093/ehjcr/ytac161; eCollection.
2021
Boone CE, Stark P.: 57-year-old woman being evaluated for reconstructive surgery. AuntMinnie.com - Case of the Day May 2021 Notes: https://my.auntminnie.com/cases/57-year-old-woman-being-evaluated-for-reconstructive-surgery/
2019
Boone C.E., Mroz T., Goodwin C.R., Witham T., Sciubba D.M.: Chapter 61: Posterior Cervical Foraminotomy. Cervical Spine Research Society Cervical Spine Surgery: Standard and Advanced Techniques. Springer, Page: 403-410, May 2019.
Westbroek, E. M., Ahmed, A. K., Pennington, Z., Goodwin, M. L., Xia, Y., Boone, C., Gailloud, P., & Sciubba, D. M.: Hypervascular Metastatic Spine Tumor Angiographic Relationships with the Artery of Adamkiewicz and Other Radiculomedullary Arteries. World neurosurgery 126: e480-e485, June 2019.
Westbroek, E. M., Ahmed, A. K., Pennington, Z., Goodwin, M. L., Xia, Y., Boone, C., Gailloud, P., & Sciubba, D. M.: Atypical Vertebral Hemangiomas Are Frequently Associated With Radiculomedullary Arteries. World neurosurgery 127: e1215-e1220, July 2019.
2018
Goodwin C.R., Boone C.E., Sciubba D.M.: Chapter 31: Anterior Cervical Spine Complications. Neurocritical Care Management of the Neurosurgical Patient. Monisha Kumar, Joshua Levine, James Schuster, and W. Andrew Kofke (eds.). Elsevier, Page: 315-322, January 2018.
2017
Boone C.E., Goodwin C.R., Hughes C., Sciubba D.M.: Chapter 53: Spinal Tumors. Handbook of Neurology, Neurosurgery, and Intensive Care for Nurses and Advanced Practice Health Professionals. Wang M, Strayer A, Harris O, Rosenberg C, Mummaneni P. (eds.). CRC Press (Taylor & Francis), Page: 391-406, December 2017.
2016
Goodwin, C. R., Boone, C. E., Pendleton, J., Elder, B. D., Wei, Z., Hsu, W., Sciubba, D. M., & Witham, T. F.: Pneumocephalus leading to the diagnosis of cerebrospinal fluid leak and esophageal perforation after cervical spine surgery. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia 26: 141-142, April 2016.
Boone CE, Goodwin CR, Anderson WS.: Iatrogenic Alzheimer disease? Amyloid-β protein transmission between humans. Neurosurgery 78(6): N17-N18, June 2016.
Goodwin, C. R., Yanamadala, V., Ruiz-Valls, A., Abu-Bonsrah, N., Shankar, G., Sankey, E. W., Boone, C., Clarke, M. J., Bilsky, M., Laufer, I., Fisher, C., Shin, J. H., & Sciubba, D. M. : A Systematic Review of Metastatic Hepatocellular Carcinoma to the Spine. World neurosurgery 91: 510-517, July 2016 Notes: doi.org/10.1016/j.wneu.2016.04.026.
Boone, C., Wojtasiewicz, T., & Anderson, W. S.: Characterization of a wearable dry EEG system. Neurosurgery 79(4): N10-N11, October 2016.
Negoita S, Boone C, Anderson WS.: Directionality of Medial Prefrontal Cortex and Hippocampal Interactions Is Task-Dependent. Neurosurgery 79(6): N22-N24, December 2016.
2015
Boone, C., Goodwin, C. R., Crane, G., Pendleton, J., & Sciubba, D.: A massive pelvic mucocele presenting as a cystic sacral mass. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia 22(11), June 2015.
Boone, C., & Anderson, W. S.: Single Neuron Markers of Memory Retrieval Confidence. Neurosurgery 77(6): N19-N20, December 2015.
2013
Boone, C., & Anderson, W. S.: Virtual Taxi Drivers: Network Interactions Underlying Memory Retrieval. Neurosurgery 73(6): N16-N17, December 2013 Notes: DOI: 10.1227/01.neu.0000438335.51481.13.