Education and Training

Medical School

MD - University of Alabama School of Medicine, Birmingham, AL


Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA
Child Neurology - Children’s Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

PhD in Neurobiology - University of Alabama School of Medicine, Birmingham, AL

Titles and Academic Titles

Attending Physician

Departments and Services




Cuddapah VA, Zhang SL, Sehgal A. (2019) Regulation of the blood-brain barrier by circadian rhythms and sleep. Trends in Neuroscience. Review. PMID: 31253251

Banka S, Sayer R, Breen C, Barton S, Pavaine J, Sheppard SE, Bedoukian E, Skraban C, Cuddapah VA, Clayton-Smith J. (2019) Genotype-phenotype specificity in Menke-Hennekam syndrome caused by missense variants in exon 30 or 31 of CREBBP. Am J Med Genet A. PMID: 30892814


Kahanovitch U*, Cuddapah VA*, Pacheco NL*, Holt LM, Mulkey DK, Percy AK, Olsen ML. (2018) MeCP2 Deficiency Leads to Loss of Glial Kir4.1. eNeuro. PMID: 29464197 * Denotes shared first- authorship


Nwaobi SE, Cuddapah VA, Patterson KC, Randolph AC, and Olsen ML. (2016) The role of glial- specific Kir4.1 in normal and pathological states of the CNS. Acta Neuropathologica. Review. PMID: 26961251


Cuddapah VA, Thompson M, Blount J, Li R, Saurabh G, and Goyal M. (2015) Hemispherectomy in hemimegalencephaly with tuberous sclerosis in a seven week old infant and a review of the literature. Pediatric Neurology. 53:452-5. PMID: 26231267

Cuddapah VA, Nwaobi SE, Percy AK, and Olsen ML. (2015) MECP2 in the regulation of neural activity: pathophysiological perspectives. Degenerative Neurological and Neuromuscular Disease. 5:103-116. Review.


Cuddapah VA, Pillai RB, Shekar KV, Lane JB, Motil KJ, Skinner SA, Tarquinio DC, Glaze DG, McGwin G, Kaufmann WE, Percy AK, Neul JL, Olsen ML. (2014) Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in Rett syndrome. Journal of Medical Genetics 51:152-8. PMID: 24399845 *Featured as the “Editor’s Choice” article.

Cuddapah VA, Robel S, Watkins S, and Sontheimer H. (2014) A neurocentric perspective on glioma invasion. Nature Reviews Neuroscience 15:455-65. Review. PMID: 24946761

Campbell SL, Robel S, Cuddapah VA, Robert S, Buckingham SC, Kahle KT, and Sontheimer H. (2014) GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor- associated epilepsy. Glia 63:23-36. PMID: 25066727


Cuddapah VA, Turner KL, Seifert S, Sontheimer H. (2013) Bradykinin-induced chemotaxis of human gliomas requires the activation of K Ca 3.1 and ClC-3. Journal of Neuroscience 33:1427-40. PMID: 23345219


McFerrin MB, Turner KL, Cuddapah VA, Sontheimer H. (2012) Differential Role of IK and BK Potassium Channels as Mediators of Intrinsic and Extrinsic Apoptotic Cell Death. Am J Physiol Cell Physiol 303:C1070-8. PMID: 22992678


Haas BR, Cuddapah VA, Watkins S, Rohn KJ, Dy TE, Sontheimer H. (2011) With-No-Lysine Kinase 3 (WNK3) Stimulates Glioma Invasion By Regulating Cell Volume. Am J Physiol Cell Physiol 301:C1150-60. PMID: 21813709

Cuddapah VA, Sontheimer H. (2011) Ion channels and transporters in cancer. 2. Ion channels and the control of cancer cell migration. Am J Physiol Cell Physiol 301:C541-9. Review. PMID: 21543740

Cuddapah VA, Habela CW, Watkins S, Moore LS, Barclay TT, Sontheimer H. (2011) Kinase activation of ClC-3 accelerates cytoplasmic condensation during mitotic cell rounding. Am J Physiol Cell Physiol 302:C527-38. PMID:22049206


Cuddapah VA and Sontheimer H (2010) Molecular interaction and functional regulation of ClC-3 by Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) in human malignant glioma. Journal of Biological Chemistry 285:11188-96. PMID: 20139089


Corey DM and Cuddapah VA (2008) Delayed Auditory Feedback Effects during Reading and Conversation Tasks: Gender Differences in Fluent Adults. Journal of Fluency Disorders 33:291- 305. PMID: 19328981