Zarazuela Zolkipli Cunningham, MBChB, MRCP Zarazuela Zolkipli Cunningham, MBChB, MRCP, is an attending physician in Mitochondrial Medicine at Children's Hospital of Philadelphia. Patient Ratings: ★★★★★ ★★★★★ | Phone: 267-426-4961 Email: email@example.com Education and Training Medical SchoolMBChB, Edinburgh University Medical School, Scotland, UK Board CertificationPediatric NeurologyPediatricsRoyal College of Pediatrics and Child Health (MRCPCH)Graduate DegreePhD, Warwick University Medical School, UK Titles and Academic Titles Attending Physician Conditions Treated Mitochondrial Disease Departments and Services Mitochondrial Medicine Division of NeurologyNeuromuscular ProgramDivision of Human Genetics Publications Papers2019 Ganetzky RD, Stendel C, McCormick EM, Zolkipli-Cunningham Z, Goldstein AC, Klopstock T, Falk MJ. MT-ATP6 Mitochondrial Disease Variants: Phenotypic and biochemical features analysis in 218 published cases and cohort of 14 new cases. Hum Mutat. 2019 Feb 14. doi: 10.1002/humu.23723. [Epub ahead of print] 2018 McCormick EM, Zolkipli-Cunningham Z, Falk MJ. Mitochondrial disease genetics update: recent insights into the molecular diagnosis and expanding phenotype of primary mitochondrial disease. Curr Opin Pediatr. 2018 Sep 7.[Epub ahead of print] Glanzman AM, Mazzone ES, Young SD, Gee R, Rose K, Mayhew A, Nelson L, Yun C, Alexander K, Darras BT, Zolkipli-Cunningham Z, Tennekoon G, Day JW, Finkel RS, Mercuri E, De Vivo DC, Baldwin R, Bishop KM, Montes J. Evaluator Training and Reliability for SMA Global Nusinersen Trials1. J Neuromuscul Dis. 2018;5(2):159-166. Zolkipli-Cunningham Z, Xiao R, Stoddart A, McCormick EM, Holberts A, Burrill N, McCormack S, Williams L, Wang X, Thompson JLP, Falk MJ. Mitochondrial disease patient motivations and barriers to participate in clinical trials. PLoS One. 2018 May 17;13(5):e0197513. Lake NJ, Webb BD, Stroud DA, Richman TR, Ruzzenente B, Compton AG, Mountford HS, Pulman J, Zangarelli C, Rio M, Boddaert N, Assouline Z, Sherpa MD, Schadt EE, Houten SM, Byrnes J, McCormick EM, Zolkipli-Cunningham Z, Haude K, Zhang Z, Retterer K, Bai R, Calvo SE, Mootha VK, Christodoulou J, Rötig A, Filipovska A, Cristian I, Falk MJ, Metodiev MD, Thorburn DR. Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome. Am J Hum Genet. 2018 Apr 5;102(4):713. 2017 Parikh S, Goldstein A, Karaa A, Koenig MK, Anselm I, Brunel-Guitton C, Christodoulou J, Cohen BH, Dimmock D, Enns GM, Falk MJ, Feigenbaum A, Frye RE, Ganesh J, Griesemer D, Haas R, Horvath R, Korson M, Kruer MC, Mancuso M, McCormack S, Josee Raboisson M, Reimschisel T, Salvarinova R, Saneto RP, Scaglia F, Shoffner J, Stacpoole PW, Sue CM, Tarnopolsky M, Van Karnebeek C, Wolfe LA, Zolkipli Cunningham Z, Rahman S, Chinnery PF. Response to Newman et al. Genet Med. 2017 Dec;19(12). Parikh S, Goldstein A, Karaa A, Koenig MK, Anselm I, Brunel-Guitton C, Christodoulou J, Cohen BH, Dimmock D, Enns GM, Falk MJ, Feigenbaum A, Frye RE, Ganesh J, Griesemer D, Haas R, Horvath R, Korson M, Kruer MC, Mancuso M, McCormack S, Raboisson MJ, Reimschisel T, Salvarinova R, Saneto RP, Scaglia F, Shoffner J, Stacpoole PW, Sue CM, Tarnopolsky M, Van Karnebeek C, Wolfe LA, Cunningham ZZ, Rahman S, Chinnery PF. Patient care standards for primary mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society. Genet Med. 2017 Dec;19(12). McCormack SE, Xiao R, Kilbaugh TJ, Karlsson M, Ganetzky RD, Cunningham ZZ, Goldstein A, Falk MJ, Damrauer SM. Hospitalizations for mitochondrial disease across the lifespan in the U.S. Mol Genet Metab. 2017 Jun;121(2):119-126. Kuszak AJ, Espey MG, Falk MJ, Holmbeck MA, Manfredi G, Shadel GS, Vernon HJ, Zolkipli-Cunningham Z. Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems. Annu Rev Pathol. 2017 Nov 3. doi: 10.1146/annurev-pathol-020117-043644. [Epub ahead of print] Zolkipli-Cunningham Z, Falk MJ. Clinical effects of chemical exposures on mitochondrial function. Toxicology. 2017 Nov 1;391:90-99. doi: 10.1016/j.tox.2017.07.009. Epub 2017 Jul 27. 2016 DeBrosse C, Nanga RP, Wilson N, D'Aquilla K, Elliott M, Hariharan H, Yan F, Wade K, Nguyen S, Worsley D, Parris-Skeete C, McCormick E, Xiao R, Cunningham ZZ, Fishbein L, Nathanson KL, Lynch DR, Stallings VA, Yudkoff M, Falk MJ, Reddy R, McCormack SE. Muscle oxidative phosphorylation quantitation using creatine chemical exchange saturation transfer (CrCEST) MRI in mitochondrial disorders. JCI Insight. 2016 Nov 3;1(18):e88207. Shen L, Diroma MA, Gonzalez M, Navarro-Gomez D, Leipzig J, Lott MT, van Oven M, Wallace DC, Muraresku CC, Zolkipli-Cunningham Z, Chinnery PF, Attimonelli M, Zuchner S, Falk MJ, Gai X. MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease. Hum Mutat. 2016 Jun;37(6):540-8. 2014 Haas RH, Zolkipli Z. Mitochondrial disorders affecting the nervous system. Semin Neurol. 2014 Jul;34(3):321-40. Declèves AE, Zolkipli Z, Satriano J, Wang L, Nakayama T, Rogac M, Le TP, Nortier JL, Farquhar MG, Naviaux RK, Sharma K. Regulation of lipid accumulation by AMP-activated kinase in high fat diet-induced kidney injury. Kidney Int. 2014 Mar;85(3):611-23. BooksChapters 2012 Zolkipli Z. Atlas of Inherited Metabolic Diseases 3rd Edition, Hodder Arnold, 2012: 302 – 308 Posters and Presentations2015 Zolkipli Z. Mitochondrial Disease Patients’ Motivations and Barriers to Participate in Clinical Trials. UMDF Mitochondrial Medicine 2015 International Symposium, Herndon, VA. June 20, 2015. Awards and Honors 2013, UMDF Burroughs WellcomeTravel Award, USA 2012, UMDF Burroughs WellcomeTravel Award, USA 2011, United Mitochondrial Disease Foundation (UMDF) Burroughs Wellcome Travel Award, USA 2011, Gerber Foundation Novice Researcher Award, USA 2009, SSIEM, Travel Award for presentation at Annual meeting, UK 2009, Research Institute Travel Award, Hospital for Sick Children, Toronto 2009, European Paediatric Neurology Society (EPNS) Travel Bursary 2009 SSIEM, 3 year Membership Scholarship Award, UK 2007, Winston Churchill Travel Fellowship, London, UK2008 Research Institute Travel Award, Hospital for Sick Children, Toronto 2003, Sir Henry John Biggleswade Prize for Best Presentation. Pediatric Regional Meeting, Cambridgeshire, UK 1991-1996, Full Scholarship, National Oil Company of Malaysia for Medical School in the UK Leadership and Memberships Memberships in Professional Organizations 2013, International Child Neurology Association 2010-present, United Mitochondrial Disease Foundation 2009-present, Society for Inborn Errors of Metabolism 2008-present, Pediatric Neurotransmitters Disease Foundation Patient Experience Ratings About the Patient Experience Rating System The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. We are committed to true transparency. 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