Mai T. Dang, MD, PhD

Mai T. Dang, MD, PhD
Mai T. Dang, MD, PhD, is a pediatric neurologist at Children's Hospital of Philadelphia.

Areas of Expertise: Neurologic complications of cancer
Locations: Buerger Center for Advanced Pediatric Care

Education and Training

Medical School

MD - University of Illinois College of Medicine, Chicago, IL


Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA


Pediatric Neurology – The Children’s Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

PhD - Molecular and Integrative Physiology, University of Illinois, Chicago, IL

Titles and Academic Titles

Attending Physician

Departments and Services

Research Interests





Yokoi F, Chen HX, Dang MT, Cheetham CC, Campbell SL, Roper SN, Sweatt JD, Li Y. Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice. PLoS One. 2015 Mar 23;10(3):e0120916. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0126539.

Yokoi F, Dang MT, Liu J, Gandre JR, Kwon K, Yuen R, Li Y. Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ΔGAG heterozygous knock-in mice. Behav Brain Res. 2015 Feb 15;279:202-10. Epub 2014 Nov 29.

Dang MT, Wehrli S, Dang CV, Curran T. The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice. PLoS One. 2015 Jul 20;10(7):e0133633.


Wang Y, Sasaoka T, Dang MT. A molecular genetic approach to uncovering the differential functions of dopamine D2 receptor isoforms. Methods Mol Biol. 2013;964:181-200.


Yokoi F, Dang MT, Zhou T, Li Y. Abnormal nuclear envelopes in the striatum and motor deficits in DYT11 myoclonus-dystonia mouse models. Hum Mol Genet. 2012 Feb 15;21(4):916-25. Epub 2011 Nov 11.

Yokoi F, Dang MT, Li Y. Improved motor performance in Dyt1 ΔGAG heterozygous knock-in mice by cerebellar Purkinje-cell specific Dyt1 conditional knocking-out. Behav Brain Res. 2012 May 1;230(2):389-98. Epub 2012 Feb 25.


Yokoi F, Dang MT, Yang G, Li J, Doroodchi A, Zhou T, Li Y. Abnormal nuclear envelope in the cerebellar Purkinje cells and impaired motor learning in DYT11 myoclonus-dystonia mouse models. Behav Brain Res. 2012 Feb 1;227(1):12-20. Epub 2011 Oct 21.

Dang MT, Yokoi F, Cheetham CC, Lu J, Vo V, Lovinger DM, Li Y. An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice. Behav Brain Res. 2012 Jan 15;226(2):465-72. Epub 2011 Oct 8.

Yokoi F, Dang MT, Li J, Standaert DG, Li Y. Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice. PLoS One. 2011;6(9):e24539. Epub 2011 Sep 12.


Agatsuma S, Dang MT, Li Y, Hiroi N. N-methyl-D-aspartic acid receptors on striatal neurons are essential for cocaine cue reactivity in mice. Biol Psychiatry. 2010 Apr 15;67(8):778-80. Epub 2010 Feb 10.


Mitsui S, Osako Y, Yokoi F, Dang MT, Yuri K, Li Y, Yamaguchi N. A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction. Eur J Neurosci. 2009 Dec;30(12):2368-78. Epub 2009 Dec 10.

Yokoi F, Dang MT, Miller CA, Marshall AG, Campbell SL, Sweatt JD, Li Y. Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in Dyt1 DeltaGAG knock-in mice. Neurosci Res. 2009 Nov;65(3):228-35. Epub 2009 Jul 18.


Yokoi F, Dang MT, Mitsui S, Li J, Li Y. Motor deficits and hyperactivity in cerebral cortex-specific Dyt1 conditional knockout mice. J Biochem. 2008 Jan;143(1):39-47. Epub 2007 Oct 23.


Dang MT, Yokoi F, Pence MA, Li Y. Motor deficits and hyperactivity in Dyt1 knockdown mice. Neurosci Res. 2006 Dec;56(4):470-4. Epub 2006 Oct 13.

Yokoi F, Dang MT, Li J, Li Y. Myoclonus, motor deficits, alterations in emotional responses and monoamine metabolism in epsilon-sarcoglycan deficient mice. J Biochem. 2006 Jul;140(1):141-6. Epub 2006 Jun 30.

Dang MT, Yokoi F, Yin HH, Lovinger DM, Wang Y, Li Y. Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15254-9. Epub 2006 Oct 2.


Dang MT, Yokoi F, McNaught KS, Jengelley TA, Jackson T, Li J, Li Y. Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystonia. Exp Neurol. 2005 Dec;196(2):452-63. Epub 2005 Oct 20.

Yokoi F, Dang MT, Mitsui S, Li Y. Exclusive paternal expression and novel alternatively spliced variants of epsilon-sarcoglycan mRNA in mouse brain. FEBS Lett. 2005 Aug 29;579(21):4822-8.


Liao S, Lin J, Dang MT, Zhang H, Kao YH, Fukuchi J, Hiipakka RA. Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid. Arch Dermatol Res. 2001 Apr;293(4):200-5.