Andrew Degnan, MD, MPhil

Andrew Degnan, MD, MPhil

Andrew Degnan, MD, MPhil, is an attending pediatric radiologist in the Division of Body Imaging of the Department of Radiology at Children’s Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - George Washington University, Washington, DC

Internship

Transitional Year - University of Pittsburgh Medical Center, Shadyside Hospital, Pittsburgh, PA

Residency

Radiology - University of Pittsburgh Medical Center, Pittsburgh, PA (Chief Resident)

Fellowship

Pediatric Radiology - Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Radiology

Graduate Degree

MPhil in Medical Sciences specializing in Radiology - University of Cambridge, Cambridge, England

Titles and Academic Titles

Attending Pediatric Radiologist

Instructor of Radiology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2018

Chetlen AL, Degnan AJ, Guelfat M, Griffith B, Itri J, Matta H, Tong A, Flug J, Toy D, Consul N, Walker E, Spalluto L, Smith AD, Krupinski E. Radiology Research Funding: Current State and Future Opportunities. Acad Radiol. 2018;25(1):26-39. doi: 10.1016/j.acra.2017.07.013

Chung CY, Alson MD, Duszak R, Degnan AJ. From imaging to reimbursement: what the pediatric radiologist needs to know about healthcare payers, documentation, coding and billing. Pediatric Radiology. 2018 doi: 10.1007/s00247-018-4104-1

Degnan AJ, Chung CY, Shah AJ. Quantitative diffusion-weighted magnetic resonance imaging assessment of chemotherapy treatment response of pediatric osteosarcoma and Ewing sarcoma malignant bone tumors. Clinical Imaging. 2018;47:9-13. doi: 10.1016/j.clinimag.2017.08.003

Degnan AJ, Ho-Fung VM. More than epiphyseal osteochondromas: updated understanding of imaging findings in dysplasia epiphysealis hemimelica (Trevor's disease). AJR Am J Roentgenol. 2018 [Accepted]

Degnan AJ, Kietz D, Grudziak J, Shah AJ. Bilateral absence of the cruciate ligaments with meniscal dysplasia: unexpected diagnosis in a child with juvenile idiopathic arthritis. Clin Imaging. 2018 Mar 26;49:193-197. doi: 10.1016/j.clinimag.2018.03.015. [Epub ahead of print]

Shi Z, Zhu C, Degnan AJ, Tian X, Li J, Chen L, Zhang X, Peng W, Chen C, Lu J, Jiang T, Saloner D, Liu Q. Identification of high- risk plaque features in intracranial atherosclerosis: initial experience using a radiomic approach. Eur Radiol. 2018 Apr 9. doi: 10.1007/s00330-018-5395-1. [Epub ahead of print]

Wang X, Zhu C, Leng Y, Degnan AJ, Lu J. Intracranial aneurysm wall enhancement associated with aneurysm rupture: a systematic review and meta-analysis. Acad Radiol. 2018 Jun 13. pii: S1076-6332(18)30244-7. doi: 10.1016/j.acra.2018.05.005. [Epub ahead of print]

Wang X, Zhu C, Ling J, Degnan AJ, Jiang T, Lu J. Knowledge-based iterative model reconstruction: Comparative image quality with low tube voltage cerebral CT angiography. Medicine (Baltimore). 2018 Jul;97(30):e11514. doi: 10.1097/MD.0000000000011514 [Epub ahead of Print]

Zhu C, Tian X, Degnan AJ, Shi Z, Zhang X, Chen L, Teng Z, Saloner D, Lu J, Liu Q. Clinical significance of intraplaque hemorrhage in low- and high-grade basilar artery stenosis on high-resolution MRI. AJNR Am J Neuroradiol. 2018 doi: 10.3174/ajnr.A5676 [Epub ahead of Print]

Zhu C, Wang X, Degnan AJ, Shi Z, Tian B, Liu Q, Hess C, Saloner D, Lu J. Intracranial unruptured aneurysm: relationship between wall enhancement and rupture risk factors on high-resolution MRI. Eur Radiol 2018 [Accepted]

Zhu C, Wang X, Degnan AJ, Shi Z, Tian B, Liu Q, Hess C, Saloner D, Lu J. Wall enhancement of intracranial unruptured aneurysm is associated with increased rupture risk and traditional risk factors. Eur Radiol. 2018 Jun 5. doi: 10.1007/s00330-018- 5522-z. [Epub ahead of print]

2017

Degnan AJ, Hemingway J, Hughes DR. Medicare utilization of vertebral augmentation 2001-2014: effects of randomized clinical trials and guidelines on vertebroplasty and kyphoplasty. Journal of the American College of Radiology. 2017;14(8):1001-1006.  doi: 10.1016/j.jacr.2017.04.026

Degnan AJ, Lee KKW, Minervini MI, Borhani AA. Metastatic extrapleural malignant solitary fibrous tumor presenting with hypoglycemia (Doege–Potter syndrome). Radiology Case Reports. 2017;12(1):113-119.

Degnan AJ, Tadros SS, Tocchio S. Pediatric neuroendocrine carcinoid tumors: review of diagnostic imaging findings and recent advances. AJR Am J Roentgenol. 2017;208:868-877. doi: 10.2214/AJR.16.17287

Degnan AJ, Tocchio S, Kurtom W, Tadros SS. Pediatric neuroendocrine carcinoid tumors: Management, pathology and imaging findings in a pediatric referral center. Pediatr Blood Cancer. 2017;64(9). doi: 10.1002/pbc.26477

Jiang Y, Peng W, Tian B, Zhu C, Chen L, Wang X, Liu Q, Wang Y, Xiang Z, Degnan AJ, Teng Z, Saloner D, Lu J. Identification and quantitative assessment of different components of intracranial atherosclerotic plaque by ex vivo 3T high-resolution multicontrast MRI. AJNR Am J Neuroradiol. 2017;38(9):1716-1722. doi:10.3174/ajnr.A5266

Rosenkrantz AB, Degnan AJ, Duszak R Jr. Documentation, coding, and billing: what abdominal radiologists need to know. Abdominal Radiology 2017 doi:10.1007/s00261-017-1235-z [Epub ahead of print]

2016

Jiang Y, Zhu C, Peng W, Degnan AJ, Chen L, Wang X, Liu Q, Wang Y, Xiang Z, Teng Z, Saloner D. Ex-vivo imaging and plaque type classification of intracranial atherosclerotic plaque using high resolution MRI. Atherosclerosis. 2016;249:10-6.

Kurtom WH, Degnan AJ, Fisher RG. Pott puffy tumor: a rare case presenting in a 5-year-old child. Consultant for Pediatricians. 2016;15(12):605-608.

Kurtom WH, Degnan AJ, Langley KG, Schrier Vergano SA. Why does this boy have multiple joint contractures? Consultant for Pediatricians. 2016;15(7):373-374.

Kurtom W, Degnan A, Quast D. Knot formation of a neonatal peripherally inserted central catheter: a rare complication of placement. J Vasc Access. 2016;17(1):e15-6.

2015

Degnan AJ, Maldjian C, Adam RJ, Fu FH, Di Domenica M. Comparison of Insall-Salvati ratios in children with acute anterior cruciate ligament tear versus a matched control population. American Journal of Roentgenology. 2015;204(1):161-166.

Degnan AJ, Maldjian C, Pantanowitz L, Kofler JK. Rare case of a radiographically occult sacral lesion detected on MRI presenting with intractable back pain. BJR Case Rep. 2015;2:20150002.

Degnan AJ, Wisnowski JL, Choi S, Ceschin R, Bhushan C, Leahy RM, et al. Altered structural and functional connectivity in late preterm preadolescence: An anatomic seed-based study of resting state networks related to the posteromedial and lateral parietal cortex. PLoS ONE. 2015; doi: 10.1371/journal.pone.0130686

Degnan AJ, Wisnowski JL, Choi S, Ceschin R, Bhushan C, Leahy RM, et al. Alterations of resting state networks and structural connectivity in relation to the prefrontal and anterior cingulate cortices in late prematurity. NeuroReport. 2015;26(1):22-26.

2014

Degnan AJ, Ceschin R, Lee V, Schmithorst VJ, Blüml S, Panigrahy A. Early metabolic development of posteromedial cortex and thalamus in humans using in vivo quantitative MR spectroscopy. Journal of Comparative Neurology. 2014;522(16):3717-3732.

Degnan AJ, Levy LM. 2014. Neuroimaging of rapidly progressive dementias, part 1: neurodegenerative etiologies. AJNR Am J Neuroradiol. 2014;35(3):418-423.

Degnan AJ, Levy LM. 2014. Neuroimaging of rapidly progressive dementias, part 2: prion, inflammatory, neoplastic, and other etiologies. AJNR Am J Neuroradiol. 2014;35(3):424-431.

Degnan AJ, Maldjian C, Adam RJ, Harner CD. Passive posterior tibial subluxation on routine knee MRI as a secondary sign of PCL tear. Radiology Research and Practice. 2014; Article ID 715439, 6 pages.

Degnan AJ, Samtani R, Paudel K, Levy LM. Neuroimaging of epilepsy: a review of MRI findings in uncommon etiologies and atypical presentations of seizures. Future Neurology. 2014;9(4):431-448.

Gruner P, Vo A, Argyelan M, Ikuta T, Degnan AJ, John M, Peters BD, Malhotra AK, Uluğ AM, Szeszko PR. Independent component analysis of resting state activity in pediatric obsessive‐compulsive disorder. Human brain mapping. 2014;35(10):5306–5315.

2013

Degnan AJ, Devulapalli KK. Predicting vascular events with iron oxide-enhanced MRI: improving cerebrovascular and cardiovascular risk stratification through imaging. Imaging in Medicine. 2013;5(6),553-566.

Levy LM, Degnan AJ, Sethi I, Henkin RI. Anatomic olfactory structural abnormalities in congenital smell loss: magnetic resonance imaging evaluation of olfactory bulb, groove, sulcal, and hippocampal morphology. Journal of computer assisted tomography. 2013;37(5):650-657.

Levy LM, Degnan AJ. GABA-based evaluation of neurologic conditions: MR spectroscopy. AJNR Am J Neuroradiol. 2013;34(2):259-65.

Liu Q, Huang J, Degnan AJ, Chen S, Gillard JH, Teng Z, Lu J. Comparison of high-resolution MRI with CT angiography and digital subtraction angiography for the evaluation of middle cerebral artery atherosclerotic steno-occlusive disease. Int J Cardiovasc Imaging. 2013;29(7):1491-1498.

Passi N, Degnan AJ, Levy LM. MR Imaging of papilledema and visual pathways: Effects of increased intracranial pressure and pathophysiologic mechanisms. AJNR Am J Neuroradiol. 2013;34(5):919-924.

Walkoff L, Degnan AJ, Ghassibi M, Jones RV, Sherman JH, Levy LM. Neuroimaging of a pilocytic astrocytoma with anaplastic features and diffusion tensor imaging characteristics. Radiology Case Reports. 2013;8(2).

2012

Degnan AJ, Gallagher G, Teng Z, Lu J, Liu Q, Gillard JH. MR angiography and imaging for the evaluation of middle cerebral artery atherosclerotic disease. AJNR Am J Neuroradiol. 2012;33(8):1427-35.

Degnan AJ, Gillard JH. Improving atherosclerosis risk assessment: looking beyond plaque accumulation to imaging of embolization and healing. Future Neurology. 2012;7(1):29-36.

Degnan AJ, Patterson AJ, Tang TY, Howarth SP, Gillard JH. Evaluation of ultrasmall superparamagnetic iron oxide-enhanced MRI of carotid atherosclerosis to assess risk of cerebrovascular and cardiovascular events: follow-up of the ATHEROMA trial. Cerebrovasc Dis. 2012;34(2):169-73.

Degnan AJ, Young VE, Gillard JH. Advances in noninvasive imaging for evaluating clinical risk and guiding therapy in carotid atherosclerosis. Expert Rev Cardiovasc Ther. 2012;10(1):37-53.

Degnan AJ, Young VE, Tang TY, Gill AB, Graves MJ, Gillard JH, et al. Ex vivo study of carotid endarterectomy specimens: quantitative relaxation times within atherosclerotic plaque tissues. Magnetic Resonance Imaging. 2012;30(7),1017-1021.

Huang J, Degnan AJ, Liu Q, Teng Z, Yue CS, Gillard JH, et al. Comparison of NASCET and WASID criteria for the measurement of intracranial stenosis using digital subtraction and computed tomography angiography of the middle cerebral artery. J Neuroradiol. 2012;39(5):342-5.

Koppula R, Degnan AJ. Ghassibi M, Duggan P, Jones R, Levy LM. Neuroimaging of tumefactive multiple sclerosis with atypical features. Radiology Case Reports. 2012;7:752.

Levy LM, Degnan AJ, Sharma S, Kelahan L, Henkin RI. Morphological changes of olfactory bulbs and grooves: initial report of supernumerary olfactory bulbs. Journal of Computer Assisted Tomography. 2012;36(4):406-9.

Patterson AJ, Degnan AJ, Walsh SR, Eltayeb M, Scout EF, Clarke JM, et al. Efficacy of VBHOM to predict outcome following major lower limb amputation. Vasc Endovascular Surg. 2012;46(5):369-73.

Teng Z, He J, Degnan AJ, Chen S, Sadat U, Bahaei NS, et al. Critical mechanical conditions around neovessels in carotid atherosclerotic plaque may promote intraplaque hemorrhage. Atherosclerosis. 2012;223(2):321-6.

2011

Degnan AJ, Levy LM. Pseudotumor cerebri: brief review of clinical syndrome and imaging findings. AJNR Am J Neuroradiol. 2011;32(11):1986-93.

Degnan AJ, Levy LM. Orbital plasmablastic lymphoma with remission following chemotherapy. Journal of Radiology Case Reports. 2011;5(2):1-7.

Degnan AJ, Levy LM. Narrowing of Meckel's cave and cavernous sinus and enlargement of the optic nerve sheath in pseudotumor cerebri. Journal of Computer Assisted Tomography. 2011;35(2):308.

Teng Z, Degnan AJ, Sadat U, Wang F, Young VE, Graves MJ, et al. Characterization of healing following atherosclerotic carotid plaque rupture in acutely symptomatic patients: an exploratory study using in vivo cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2011;13:64.

Young VEL, Degnan AJ, Gillard JH. Advances in contrast media for vascular imaging of atherosclerosis. Imaging in Medicine. 2011;3(3):353-66.

2010

Degnan AJ, Bulas DI, Sze RW. Ileal atresia with meconium peritonitis: Fetal MRI evaluation. Journal of Radiology Case Reports. 2010;4(3):15-8.

Lee H, Hoffman C, Kingsley P, Degnan A, Cohen O, Prohovnik I. Enhanced detection of diffusion reductions in Creutzfeldt- Jakob disease at a higher B factor. AJNR American Journal of Neuroradiology. 2010;31(1):49-54.

Smyser CD, Inder TE, Shimony JS, Hill JE, Degnan AJ, Snyder AZ, et al. Longitudinal analysis of neural network development in preterm infants. Cerebral Cortex. 2010;20(12):2852-62.

2009

Freishtat RJ, Natale J, Benton AS, Cohen J, Sharron M, Wiles AA, Ngor WM, Mojgani B, Bradbury M, Degnan AJ, et al. Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity. Am J Respir Crit Care Med. 2009;179(6):467-73.

Books

Chapters

2016

Degnan AJ, Levy LM. Chapter 5: DWI and DTI in aging. In: Leite C, Castillo M, eds. Diffusion weighted and diffusion tensor imaging: a clinical guide. 1st ed. New York, NY: Thieme; 2016.

Posters and Presentations

2018

Degnan AJ, Biko DM, White AM, Servaes S, Otero HJ, Fox WW, Shaffer T, Zhang H, Saul D. Back to the future: perfluorochemical liquid ventilation and its imaging appearances. Society for Pediatric Radiology; Nashville, TN: May 15, 2018.

Degnan AJ, Chung CY, Duszak R, Alson MD. From imaging to reimbursement: what the pediatric radiologist needs to know about coding and billing. Society for Pediatric Radiology; Nashville, TN: May 15, 2018.

Degnan AJ, Saul D, Shaffer TH, Fox W, Zhang H. Partial Liquid Ventilation with Perfluorooctylbromide Highlights Heterogeneous Ventilation Patterns in Bronchopulmonary Dysplasia. Pediatric Academic Societies; Toronto, Canada: May 5, 2018.

Degnan AJ, Wang DJ, Ahrens-Nicklas RC, Ficicioglu C. Magnetic resonance spectroscopy monitors bone marrow response to enzyme replacement and substrate reduction therapy in Gaucher disease. American College of Medical Genetics and    Genomics Clinical Genetics Meeting; Charlotte, NC: April 13, 2018.

Degnan AJ, Saul D, Shaffer TH, Fox W, Zhang H. Partial Liquid Ventilation with Perfluorooctylbromide Highlights Heterogeneous Ventilation Patterns in Bronchopulmonary Dysplasia. Eastern Society of Pediatric Research; Philadelphia, PA: March 17, 2018.

2017

Degnan AJ, Scotti-Degnan CM, Ghodadra A, Rees M. Lessons from cognitive psychology and aviation for understanding and avoiding diagnostic error by radiology residents on-call. Association of University Radiologists; Hollywood, FL: May 9, 2017.

Degnan AJ, Scotti-Degnan CM. Landing safely: reducing diagnostic error on-call through education, workflow and cognitive engineering for radiology residents. Association of University Radiologists; Hollywood, FL: May 9, 2017.

Hakim CM, Chang Sen L, Degnan A, Delic J, Pai S, Sagreiya H, Sparrow M, Thomas E, Yannes M, Gur D. The effect of    prevalence of disease on performance of residents and fellows during training for interpreting DBT in a test-train-test observer study. (10136-2) SPIE Medical Imaging; Orlando, FL: February 12, 2017.

2016

Chung CY, Degnan AJ, Shah A. Assessment of pediatric musculoskeletal tumors and treatment response on diffusion weighted MRI. Radiological Society of North America; Chicago, IL: December 1, 2016.

Jiang Y, Zhu C, Degnan AJ, Peng W, Chen L, Wang X, Liu Q, Wang Y, Xiang Z, Teng Z, Saloner D, Lu J. Ex-vivo quantitative imaging and qualitative plaque type classification of intracranial atherosclerotic plaque using high resolution MRI. (0598, Summa cum laude award) International Society for Magnetic Resonance in Medicine; Singapore: May 11, 2016.

Invited Lectures

2017

Chetlen AL, Degnan AJ, Tong A, Krupinski EA. The impact of federal and non-federal funding sources on radiology research (Session 210B). Association of University Radiologists; Hollywood, FL: May 9, 2017.

Degnan AJ. From imaging study to reimbursement: what the pediatric radiologist needs to know about coding and billing. Children’s Hospital of Philadelphia, Philadelphia, PA; October 20, 2017.

Degnan AJ. Diagnostic imaging: role of the radiologist, appropriate imaging selection, and imaging modalities. University of Pittsburgh School of Medicine, Pittsburgh, PA; January 20, 2017. Educational lecture to visiting medical students from Xiangya, China.

2016

Degnan AJ. MACRA (Medicare Access and CHIP Reauthorization Act): the future of medicare payments for radiologists. University of Pittsburgh Medical Center, Department of Radiology; Pittsburgh, PA: December 21, 2016. Health policy lecture to department.

Degnan AJ. Reviewing for Radiology: How I do it. Radiological Society of North America; Chicago, IL: November 30, 2016.

Degnan AJ. Introduction to diagnostic radiology. University of Pittsburgh School of Medicine, Pittsburgh, PA; August 31, 2016. Educational lecture to medical students.

Awards and Honors

2016-2017, Radiology Editor’s Recognition Award with Special Distinction
2016, American Institute of Radiologic Pathology (AIRP) Best Case Award
2016, American College of Radiology James M. Moorefield, MD Fellowship in Economics & Health Policy
2015, RSNA Roentgen Resident and Fellow Research Award
2015, Pennsylvania Radiological Society Leadership Scholarship
2014, RSNA William W. Olmsted Editorial Fellow
2010, Alpha Omega Alpha
2006, Phi Beta Kappa
2004-2007, Outstanding Academic Achievement Award

Editorial and Academic Positions

Editorial Positions

2017-present, Editorial Board, Clinical Examples in Radiology
2012-present, Journal Reviewer, Radiology
2012-present, Journal Reviewer, PLoS One
2012-present, Journal Reviewer, JMRI
2012-present, Journal Reviewer, BJR Case Reports
2012-present, Journal Reviewer, Neuroradiology
2012-present, Journal Reviewer, BMC Medical Imaging
2012-present, Journal Reviewer, Current Problems in Diagnostic Imaging

Leadership and Memberships

Memberships in Professional Organizations

2018-present, Society of Pediatric Radiology
 - 2018-present, MSK Imaging Committee
 - 2018-present, Public Policy Committee
2016-present, American College of Radiology
 - 2017-present, Coding and Nomenclature Committee
 - 2017-present, CPT Editorial Panel Advisor
 - 2016-present, MACRA Committee