Marie M. Gleason, MD, FAAP, FACC

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Marie M. Gleason, MD, FAAP, FACC, is Associate Chief of the Division of Cardiology and Director of Outpatient and Community Cardiology for the Division of Cardiology at Children’s Hospital of Philadelphia.

Areas of Expertise: Echocardiography, Fetal echocardiography, General pediatric cardiology, Newborn congenital heart disease, Pediatric hyperlipidemia
Locations: Main Campus; Specialty Care, Abington; Specialty Care, Exton; Specialty Care & Surgery Center, King of Prussia; Specialty Care, Lancaster; Specialty Care & Surgery Center, Brandywine Valley; CHOP at Lancaster General Health

Phone: 215-590-4040


“As a general pediatric cardiologist for more than 30 years, I have cared for patients with many, many cardiac conditions,” says Marie M. Gleason, MD.

Dr. Gleason has had the pleasure of helping many patients overcome grave challenges and grow to flourishing adulthood.

“Performing fetal echocardiograms, diagnosing heart disease, and seeing those patients and families though cardiac procedures and then watching the children grow up has been very rewarding,” Dr. Gleason says.

Dr. Gleason is Associate Chief of the Division of Cardiology and Director of Outpatient and Community Cardiology for the Division of Cardiology at Children’s Hospital of Philadelphia (CHOP) and Clinical Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

As a leader of CHOP’s cardiology team, Dr. Gleason ensures that patients with a wide variety of cardiac conditions receive appropriate care and support, not only at times of crisis but throughout their lives.

“Patients and families should know that everyone who works in the Cardiac Center wants them to have the most positive experience possible, and that we work hard to do the very best that we can for patients and families at all levels,” Dr. Gleason says.

“I am fascinated by the ability of complex heart deformities to function better than expected after cardiac surgeries,” Dr. Gleason says, and those successes depend on care that goes far beyond surgery.

“Our field is already evolving into one that looks at the patient as a whole, not just the heart, particularly with regards to psychosocial development. This is so important for families,” Says Dr. Gleason.

The Cardiac Center at CHOP handles one of the largest volumes of outpatient cardiac care in the nation, with more than 35,000 patient visits annually. Dr. Gleason oversees outpatient operations at the Main Campus in Philadelphia and satellite locations in Pennsylvania and New Jersey. She also oversees a team that is on call around the clock for a network of community hospitals in Pennsylvania who provide cardiology consultative services when needed to evaluate suspected cardiac problems in newborns, infants, children and teenagers.

In addition to leading outpatient and community care, Dr. Gleason is also a fetal cardiologist, evaluating echocardiograms (ultrasound of the fetal heart) at special screening sessions at community hospitals in Pennsylvania.

Dr. Gleason has lectured around the region and the country on such topics as the basics of echocardiography, cardiac effects of rheumatic fever and Kawasaki disease, and conotruncal heart defects. General pediatricians often seek advice on evaluating palpitations, chest pain and fainting, asking when it is appropriate to refer care to a pediatric cardiologist — Dr. Gleason lectures frequently on these important topics.

Dr. Gleason has published numerous articles in such journals as Circulation, American Journal of Cardiology, American Heart Journal, The Journal of Thoracic and Cardiovascular Surgery, and Congenital Heart Disease. She has authored several chapters for textbooks for medical students and practicing physicians, and is co-editor of the textbook Pediatric Practice: Cardiology, a reference for general pediatricians and others as they manage heart problems.

Dr. Gleason was one of the investigators on a nationwide study of the effectiveness of two types of medication for Marfan syndrome, which was funded by the National Institutes of Health.

D. Gleason graduated summa cum laude with a bachelor’s degree in biology from St. John’s University, Queens, NY. She received her medical degree from the New York University School of Medicine and was elected a member of Alpha Omega Alpha, the medical honor society. She completed all of her training at CHOP, including an internship and residency in pediatrics and a fellowship in pediatric cardiology.

Education and Training

Medical School

MD - New York University School of Medicine, New York, NY


Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA


Pediatric Cardiology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

American Board of Pediatrics
American Board of Pediatrics/Pediatric Cardiology

Titles and Academic Titles

Associate Chief of Outpatient and Community Cardiology

Director, Outpatient and Community Cardiology

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services



Collins RT 2nd, Aziz PF, Gleason MM, Kaplan PB, Shah MJ. Abnormalities of cardiac repolarization in Williams syndrome. Am J Cardiol. 2010 Oct 1;106(7):1029-33. Epub 2010 Aug 11.

Collins RT 2nd, Ryan M, Gleason MM. Images in cardiovascular medicine. Mitral arcade: a rare cause of fatigue in an 18-year-old female. Circulation. 2010 Apr 20;121(15):e379-83. No abstract available.

Wernovsky G, Rome JJ, Tabbutt S, Rychik J, Cohen MS, Paridon SM, Webb G, Dodds KM, Gallagher MA, Fleck DA, Spray TL, Vetter VL, Gleason MM. Guidelines for the outpatient management of complex congenital heart disease. Congenit Heart Dis. 2006 Jan;1(1-2):10-26. Review.

Pastuszko P, Rome JJ, Gleason MM, Bellah RD, Montenegro LM, Gaynor JW. Hemoptysis after CardioSEAL device embolization of a venous collateral after the Fontan operation. J Thorac Cardiovasc Surg. 2005 Jun;129(6):1447-8. PMID: 15942597.

McElhinney DB, Yang SG, Hogarty AN, Rychik J, Gleason MM, Zachary CH, Rome JJ, Karl TR, Decampli WM, Spray TL, Gaynor JW. Recurrent arch obstruction after repair of isolated coarctation of the aorta in neonates and young infants: is low weight a risk factor? J Thorac Cardiovasc Surg. 2001 Nov;122(5):883-90.

Raff GW, Gaynor JW, Weinberg PM, Spray TL, Gleason M. Membranous subpulmonic stenosis associated with ventricular septal defect and aortic insufficiency. J Am Soc Echocardiogr. 2000 Jan;13(1):58-60.