Christina E. Holbein, PhD

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Christina E. Holbein, PhD, is a psychologist with the Department of Child & Adolescent Psychiatry and Behavioral Sciences and the Division of Gastroenterology, Hepatology & Nutrition/Center for Inflammatory Bowel Disease at Children's Hospital of Philadelphia.

Areas of Expertise: Pediatric inflammatory bowel disease, Very early onset inflammatory bowel disease (VEO-IBD), Psychosocial screening as part of routine clinical care, Evidence-based treatment of chronic pain and discomfort, Behavioral treatment for constipation and encopresis, Treatment adherence, self-management, and transition to adult medical care
Locations: Buerger Center for Advanced Pediatric Care; Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Internship

Predoctoral Internship - Pediatric Psychology & Psychiatry Department, Nemours/A. I. duPont Hospital for Children, Wilmington, DE

Fellowship

NIH T32 Postdoctoral Fellow - Center for Adherence and Self-Management, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Undergraduate Degree

BS in Psychology - The Ohio State University, Columbus, OH

Graduate Degree

PhD in Child and Family Clinical Psychology - Loyola University Chicago, Chicago, IL
MA in Child and Family Clinical Psychology - Loyola University Chicago, Chicago, IL

Titles and Academic Titles

Psychologist

Conditions Treated

Departments and Services

Research Interests

Psychosocial adjustment to pediatric inflammatory bowel disease (and other chronic health conditions)
Treatment adherence and self-management for youth with chronic health conditions

Publications

Papers

2021

Holbein, C. E., Plevinsky, J., Patel, T., Conrad, M., & Kelsen, J. (2021). Pediatric global health and gastrointestinal symptoms in children with very early-onset inflammatory bowel disease. Journal of Pediatric Psychology, 46(7), 747-756.

2020

Hommel, K., Carmody, J., Hershey, A., Holbein, C. E., Kabbouche, M., Peugh, J., & Powers, S. (2020). Digital therapeutic self-management intervention in adolescents with migraine: Feasibility and preliminary efficacy of “Migraine Manager.” Headache, 60(6), 1103-1110.

Holbein, C.E., Peugh, J., Veldtman, G.R., Apers, S., Luyckx, K., … Moons, P. (2020). Health behaviours reported by adults with congenital heart disease across 15 countries. European Journal of Preventative Cardiology, 27(10), 1077-1087.

2019

Moons, P., Luyckx, K., Kovacs, A.H., Holbein, C.E., Thomet, C., … Apers, S. (2019). Prevalence and effects of cigarette smoking, cannabis consumption and co-use in adults with congenital heart disease from 15 countries. Canadian Journal of Cardiology, 35(12), 1842-1850.

Driscoll, C. F., Murray, C. B., Holbein, C. E., Stiles-Shields, C., Cuevas, G., & Holmbeck, G. N. (2019). Camp-based psychosocial intervention dosage and changes in independence in young people with spina bifida. Developmental Medicine & Child Neurology, 61(12), 1392-1399.

Ramsey, R. R., Carmody, J., Holbein, C. E., Guilbert, T. W., & Hommel, K. A. (2019). Examination of the uses, needs and preferences for health technology use in adolescents with asthma. Journal of Asthma, 56(9), 964-972.

Holbein, C. E., Veldtman, G. R., Moons, P., Kovacs, A. H., Luyckx, K., Apers, S., … Cedars, A. (2019). Perceived health mediates effects of physical activity on quality of life in patients with a Fontan circulation. American Journal of Cardiology, 124(1), 144-150.

Holbein, C. E., Smith, A. W., Peugh, J., & Modi, A. C. (2019). Allocation of treatment responsibility in adolescents with epilepsy: Associations with cognitive skills and medication adherence. Journal of Pediatric Psychology, 44(1), 72-83.

2018

Ramsey, R. R., Carmody, J., Holbein, C. E., Guilbert, T. W., & Hommel, K. A. Examination of the uses, needs and preferences for health technology use in adolescents with asthma. J Asthma. 2018 Sep 12:1-9. doi: 10.1080/02770903.2018.1514048. [Epub ahead of print]

Holbein, C. E., Smith, A. W., Peugh, J., & Modi, A. C. Allocation of treatment responsibility in adolescents with epilepsy: Associations with cognitive skills and medication adherence. J Pediatr Psychol. 2018 Feb 13. doi: 10.1093/jpepsy/jsy006. [Epub ahead of print]

McGrady, M. E., Holbein, C. E., Smith, A. W., Morrison, C. F., Hommel, K. A., Modi, A. C., … Ramsey, R. R.. An independent evaluation of the accuracy and usability of adherence electronic monitoring devices. Ann Intern Med. 2018 Sep 18;169(6):419-422. doi: 10.7326/M17-3306. Epub 2018 May 22.

Ramsey, R. R., Holbein, C. E., Powers, S. W., Hershey, A. D., Kabbouche, M. A., O’Brien, H. L., … Hommel, K. A. Use of a mobile phone application and progressive reminder system to improve adherence to daily prevention treatment in adolescents and young adults with migraine. Cephalalgia. 2018 Dec;38(14):2035-2044. doi: 10.1177/0333102418756864. Epub 2018 Apr 10.

Holbein, C. E., Fogelman, N. D., Hommel, K. A.,  Rassart, J., Apers, S., Moons, P., … Veldtman, G. R.. A multinational observational investigation of illness perceptions and quality of life among patients with a Fontan circulation. Congenit Heart Dis. 2018 May;13(3):392-400. doi: 10.1111/chd.12583. Epub 2018 Jan 3.

Brida, M., Grbcic, S., Holbein, C. E., & Veldtman, G. R. Editorial: Bridging the psychological issues of living with the Fontan circulation. Int J Cardiol. 2018 Jun 1;260:72-73. doi: 10.1016/j.ijcard.2018.02.105.

Holbein, C. E., Carmody, J. K., & Hommel, K. A. Topical Review: Adherence interventions for youth on gluten-free diets. J Pediatr Psychol. 2018 May 1;43(4):392-401. doi: 10.1093/jpepsy/jsx138.

2017

Holbein, C. E., Peugh, J., & Holmbeck, G. N. (2017). Social skills in youth with spina bifida: A longitudinal multimethod investigation comparing biopsychosocial predictors. Journal of Pediatric Psychology, 42(10), 1133-1143.

Holbein, C. E., Zebracki, K., Bechtel, C. F., Papadakis, J. L., Bruno, E. F., & Holmbeck, G. N. (2017). Milestone achievement in emerging adulthood: A longitudinal investigation of parental expectations in a sample of young people with spina bifida. Developmental Medicine & Child Neurology, 59(3), 311-316.

2015

Holbein, C. E., Lennon, J. M., Kolbuck, V. D., Zebracki, K., Roache, C., & Holmbeck, G. N. (2015). Observed differences in social behaviors exhibited in peer interactions between youth with spina bifida and their peers: Neuropsychological correlates. Journal of Pediatric Psychology, 40(3), 320-335.

2014

Holbein, C. E., Zebracki, K., & Holmbeck, G. N. (2014). Development and validation of the Peer Interaction Macro-coding System scales (PIMS): A new tool for observational measurement of social competence in youth with spina bifida. Psychological Assessment, 26(4), 1235-1246.

2013

Holbein, C. E., Murray, C. B., Psihogios, A. M., Wasserman, R. M., Essner, B. S., O’Hara, L. K., & Holmbeck, G. N. (2013). A camp-based psychosocial intervention to promote independence and social function in individuals with spina bifida: Moderators of treatment effectiveness. Journal of Pediatric Psychology, 38(4), 412-424.

2012

Devine, K. A., Holbein, C. E., Psihogios, A. M., Amaro, C. M., & Hombeck, G. N. (2012). Individual adjustment, parental functioning, and perceived social support in Hispanic and non-Hispanic white mothers and fathers of children with spina bifida. Journal of Pediatric Psychology, 37(7), 769-778.

2010

Boyle, B., Mackner, L. M., Ross, C. E., Moses, J., Kumar, S., & Crandall, W. V. (2010). A single-center experience with methotrexate after thiopurine therapy in pediatric Crohn’s disease. Journal of Pediatric Gastroenterology & Nutrition, 51(6): 714-717.

Books

Chapters

2020

Ramsey, R. R., & Holbein, C. E. (2020). Treatment adherence within consultation-liaison services. In K. Kullgren & B. Carter (Eds.), Clinician handbook of pediatric psychological consultation in medical settings. New York, NY: Springer.

2016

Lennon, J. M., Psihogios, A. M.., Murray, C. B., Holbein, C. E., & Holmbeck, G. N. (2016). Promoting resilience during the transition to adolescence for chronically ill children and their families. In M. Ferrari & C. DeMichelis (Eds.), Child and adolescent resilience within medical contexts (pp. 51-75). New York, NY: Springer.

Posters and Presentations

2022

Holbein, C., Andorko, N., & Turner, E. (2022, October). The role of GI Psychology consultation as part of multidisciplinary care for children with very early-onset inflammatory bowel disease (VEO-IBD) and their families. Poster to be presented at the annual meeting of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), Orlando, FL.

Rodriguez, K., Turner, E., Baber, K., Szabo, M., Mayer-Brown, S., Holbein, C., Wilkes, C., Fussner, L., Boyer, B., Bass, R., Diamond, T., Mitchel, E., Moore, H., Graham, K., Shah, A., Piccoli, D., Rand, L., & Maxwell, E. (2022, October). Incorporating pediatric psychologists in didactic training for future pediatric gastroenterologists. Poster to be presented at the annual meeting of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), Orlando, FL.

Holbein, C. E., Vellanki, S., Boateng, A., Pressman, N., Sibinga, E. M. S., Mascarenhas, M. R., & Albenberg, L. A. (2022, April). Patient experiences with a live video mindfulness pilot intervention for youth with inflammatory bowel disease. Oral symposium presentation presented at the Society of Pediatric Psychology Annual Conference, Phoenix, AZ.

Holbein, C., Andorko, N., & Turner, E. (2022, April). Pediatric psychology consultation and intervention for children with very early-onset inflammatory bowel disease (VEO-IBD) and their families. Poster presented at the Society of Pediatric Psychology Annual Conference, Phoenix, AZ.

2021

Vellanki, S., Albenberg, L., Mascarenhas, M., Sbingba, E., Holbein, C. (2021, November). Live video mindfulness program is a safe, feasible, and acceptable intervention for youth with inflammatory bowel disease. Abstract presented at the annual meeting of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), Nashville, TN.

Grimes, L., Breton, J., Benitez, A., Holbein, C., & Albenberg, L. (2021, April/May). Effects of the COVID-19 pandemic on children (and parents of children) living with inflammatory bowel disease. Poster presented at the Pediatric Academic Societies (PAS) 2021 Virtual meeting.

2020

Holbein, C., Conrad, M., Patel, T., Zilber, S., & Kelsen, J. (2020, March). Parent-reported gastrointestinal symptoms and global health in children with very early onset inflammatory bowel disease. Poster presented at the Society of Pediatric Psychology Annual Conference, Dallas, TX. https://societyofpediatricpsychology.org/node/726

2019

Holbein, C. E., & Hommel, K. (2019, August). Lessons learned in study development and methodology in a self-management study of young adults with congenital heart disease. Oral symposium presentation at the American Psychological Association 127th Annual Convention, Chicago, IL.

Invited Lectures

2022

Holbein, C. E., & Rodriguez, K. O. (2022, March). GI Psychology within an interdisciplinary team. Invited presentation for the GI Psychology Training Didactics Series, Division of Child & Adolescent Psychiatry and Behavioral Sciences, Children’s Hospital of Philadelphia, Philadelphia, PA.

Turner, E., Szabo, M., & Holbein, C. E. (2022, February). Psychosocial aspects of chronic GI conditions. Invited presentation for the GI Psychology Training Didactics Series, Division of Child & Adolescent Psychiatry and Behavioral Sciences, Children’s Hospital of Philadelphia, Philadelphia, PA.

Holbein, C. E. (2022, February). Pediatric IBD psychosocial updates and resources. Invited presentation for IBD Education Day 2022, Children’s Hospital of Philadelphia, Philadelphia, PA.

2021

Holbein, C. E., & Turner, E. (2021, June). Psychosocial aspects of pediatric inflammatory bowel disease. Invited presentation for Fellows Chief Rounds, Division of Gastroenterology, Hepatology & Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA.

Holbein, C. E. (2021, April). Pandemic mental health and IBD. Invited presentation for the Virtual Wellness Village, Crohn’s and Colitis Foundation.

Holbein, C. E., & Fussner, L. (2021, February). Self-management and treatment adherence for pediatric GI patients. Invited didactic presentation for Fellows Chief Rounds, Division of Gastroenterology, Hepatology & Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA.

Holbein, C. E., & Gulamali, M. (2021, February). Psychosocial functioning in pediatric IBD and CHOP resources. Invited presentation for IBD Education Day 2021, Children’s Hospital of Philadelphia, Philadelphia, PA.

2020

Barakat, L., & Holbein, C. E. (2020, November/December). Exposure and impact: How pediatric patients and families experience COVID-19. Invited presentation for Pediatric Psychology Professional Engagement & Development Initiative series, Children’s Hospital of Philadelphia, Philadelphia, PA.

Grossman, A. B., & Holbein, C. E. (2020, September). Medical and psychosocial considerations in the diagnosis and treatment of inflammatory bowel disease. Invited presentation for Updates in Primary Care Webinar series, Children’s Hospital of Philadelphia, Philadelphia, PA.

Holbein, C. E., & Mayer-Brown, S. (2020, June). Coping with stress and burnout as a healthcare provider. Invited didactic presentation for Fellows Chief Rounds, Division of Gastroenterology, Hepatology & Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA.

Awards and Honors

2018, Illinois Spina Bifida Association Professional Advisory Council Research Award
2015, Midwestern Association of Graduate Schools Distinguished Thesis Award
2014, Society of Pediatric Psychology Student Poster Award
2014-2015, Arthur J. Schmitt Dissertation Fellowship, Arthur J. Schmitt Foundation
2012, CVS Caremark Community Grant

Editorial and Academic Positions

Editorial Positions

2021-present, Independent Reviewer, Clinical Practice in Pediatric Psychology
2017-present, Independent Reviewer, Journal of Pediatric Psychology

Academic and Institutional Committees

2019-present, Training Advisory Committee

Leadership and Memberships

Memberships in Professional Organizations

American Psychological Association
 - Division 54: Society of Pediatric Psychology
 - Adherence Special Interest Group (SIG) Member
 - Pediatric Gastroenterology SIG
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