Education and Training
Postdoctoral Fellow - Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
American Board of Medical Genetics and Genomics
BS in Biology - Pennsylvania State University, State College, PA
PhD in Biology - Texas A&M University, College Station, TX
Titles and Academic Titles
Director, Division of Genomic Diagnostics
Assistant Professor of Clinical Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine
Departments and Services
Mundy SA, Krock BL, Mao R, Shen JJ: BRAT1-related disease-identification of a patient without early lethality. Am J Med Genet A. 2016 Mar;170(3):699-702. Epub 2015 Oct 22.
Abou Tayoun AN, Krock B, Spinner NB1. Sequencing-based diagnostics for pediatric genetic diseases: progress and potential. Expert Rev Mol Diagn. 2016 Sep;16(9):987-99. Epub 2016 Aug 17.
Viktor Lukacs, Jayani Mathur, Rong Mao, Pinar Bayrak-Toydemir, Melinda Procter, Stuart M. Calahan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day, David A Stevenson, Ardem Patapoutian, Bryan L. Krock: Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. Nat Commun. 2015 Sep 21;6:8329.
Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration. Acta Neuropathol. 2015 Sep;130(3):363-72. Epub 2015 May 29.
Krock BL, Eisinger-Mathason TS, Giannoukos DN, Shay JE, Gohil M, Lee DS, Nakazawa MS, Sesen J, Skuli N, Simon MC.: The aryl hydrocarbon receptor nuclear translator is an essential regulator of murine hematopoietic stem cell viability. Blood 125(21): 3263-72, May 2015.
Krock Bryan L, Perkins Brian D: The Par-PrkC polarity complex is required for cilia growth in zebrafish photoreceptors. PLoS One. 2014 Aug 21;9(8):e104661.
Leoni Chiara, Stevenson David A, Geiersbach Katherine B, Paxton Christian N, Krock Bryan L, Mao Rong, Rope Alan F: Neural tube defects and atypical deletion on 22q11.2. American journal of medical genetics. Am J Med Genet A. 2014 Nov;164A(11):2701-6.
Shay Jessica E S, Imtiyaz Hongxia Z, Sivanand Sharanya, Durham Amy C, Skuli Nicolas, Hsu Sarah, Mucaj Vera, Eisinger-Mathason T S Karin, Krock Bryan L, Giannoukos Dionysios N, Simon M Celeste: Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer. Carcinogenesis. 2014 May;35(5):1067-77 Epub 2014 Jan 9.
Wagage Sagie, John Beena, Krock Bryan L, Hall Aisling O'Hara, Randall Louise M, Karp Christopher L, Simon M Celeste, Hunter Christopher A: The aryl hydrocarbon receptor promotes IL-10 production by NK cells. J Immunol. 2014 Feb 15;192(4):1661-70. Epub 2014 Jan 8.
Bryan L. Krock, Viktor Lukacs, Jayanti Mathur, Rong Mao, Pinar Bayrak-Toydemir, Melinda Procter, Stuart M. Cahalan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day, David A. Stevenson, Ardem Patapoutian: Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. American Society of Human Genetics Annual Meeting, Baltimore, MD.
Bryan L. Krock, Rong Mao, D. Hunter Best, Elaine Lyon: Genomic Applications in Inherited Genetic Disorders. Genomic Applications in Pathology. George Netto and Iris Schrijver (eds.). Springer New York, Page: 535-551, 2015.
Posters and Presentations
Krock BL. "Discovery and Diagnoses: Interrogating the Genome in Pediatric Disease," Keynote Address - Penn State Lehigh Valley Regional Undergraduate Research Symposium Center Valley, PA
Krock BL. "Discovery and Diagnoses: Interrogating the Genome in Pediatric Disease," Keynote Address - Undergraduate Research at the Capitol Harrisburg, PA
Awards and Honors
2006, Texas A&M University Faculty of Neuroscience Spring Symposium Poster Contest, First Place
2006, Texas A&M University Department of Biology Recruiting Weekend Poster Comp edition Winner
2007, Texas and Southern Plains Zebrafish Conference Graduate Student Presentation Competition: First Place
2008, Lawrence Dillon Distinguished Graduate Student Award (given to top PhD candidate in the Biology Department)
2010, Individual Ruth F. Kirschstein F32 National Research Service award NRSA Award
2014, Roberts Memorial Fund Research Award, ARUP Laboratories
Editorial and Academic Positions
2016-Present, Assistant Editor Laboratory Medicine
Leadership and Memberships
2014-2015 Association for Molecular Pathology Clinical Practice Committee
2016-Present American College of Medical Genetics and Genomics (Subcommittee - Determining content of clinical gene panels)
Patient Experience Ratings
About the Patient Experience Rating System
The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient's protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments.
Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care.
The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.