Ann-Marie Leahey, MD

Ann-Marie  Leahey, MD

Ann-Marie Leahey, MD, is an attending physician at CHOP’s Cancer Center who specializes in treating children with malignant tumors of the eye.

Areas of Expertise: Retinoblastoma
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

I am responsible for caring for patients with retinoblastoma (a malignant tumor of the retina) and am in charge of The Children's Hospital of Philadelphia retinoblastoma clinical trials. I succeed the preeminent Dr. Anna Meadows in this position, having been fortunate to be trained by her for the last 20 years.

Retinoblastoma was one of the last childhood cancer frontiers to be conquered. Previously, therapy involved radiation therapy and often surgical removal of the eye (enucleation). Children’s Hospital was among the first to pioneer systemic chemotherapy for these patients, and we partner with the renowned ophthalmologist Dr. Carol Shields at Wills Eye Institute.

Now systemic chemotherapy, used with local ophthalmic therapy, can eliminate the need for radiation therapy and/or enucleation in many patients. Historically, approximately 10 percent of children with the genetic form of the disease developed a deadly tumor called pineoblastoma. With systemic chemotherapy, we are preventing the majority of these tumors from developing.

Children's Hospital has the only certified laboratory in the U.S. to provide genetic testing for retinoblastoma. Our Cancer Predisposition Program, run by my colleague Dr. Garrett Brodeur, provides detailed genetic counseling. We also work closely with scientists here at the University of Pennsylvania in conducting groundbreaking research into the possible causes of retinoblastoma.

I believe in hands on, patient- and family-centered care. I am in constant contact with my patients’ local pediatricians and oncologists since our patients come from all over the U.S. Our goal is to increase the number of children with retinoblastoma who can be cured and who can retain vision. Our expert clinical team and research efforts are all focused on that goal.

 

Education and Training

Medical School

Dartmouth-Brown Program in Medicine (MD), Providence, RI

Internship

Pediatrics, The Mount Sinai Hospital, New York, NY

Residency

Pediatrics, The Mount Sinai Hospital, New York, NY

Fellowship

Hematology/Oncology, The Children's Hospital of Philadelphia, PA

Bone Marrow Transplantation, Fred Hutchinson Cancer Center, Seattle, WA

Board Certification

American Board of Pediatrics
American Board of Pediatrics/Pediatric Hematology/Oncology

Undergraduate Degree

Dartmouth College (BA, English), Providence, RI

Titles and Academic Titles

Attending physician

Clinical professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Publications

Papers

2015

DiDomenico C, Clerico D, Leahey A: Lack of vincristine infiltrates in patients with retinoblastoma receiving chemotherapy by peripheral intravenous lines. Pediatric Blood and Cancer Apr 2015 Notes: Epub ahead of print.

2013

Shields CL, Kaliki S, Al-Dahmash S, Rojanaporn D, Leahey A, Griffin G, Jabbour P, Shields JA: Management of advanced retinoblastoma with intravenous chemotherapy then intra-arterial chemotherapy as alternative to enucleation. Retina 33(10): 2103-9, Nov-Dec 2013.

Ramasubramanian A, Kytasty C, Meadows AT, Shields JA, Leahey A, Shields CL: Incidence of pineal gland cyst and pineoblastoma in children with retinoblastoma during the chemoreduction era. American Journal of Ophthalmology 156(4): 825-9, Oct 2013.

Books

Chapters

2002

Leahey A. Mediastinal mass. In: Schwartz MW, editor. Clinical handbook of pediatrics. Baltimore: Williams & Wilkins; 2002.

1999

Leahey A. Mediastinal mass. In: Schwartz MW, editor. Clinical handbook of pediatrics. Baltimore: Williams & Wilkins; 1999.

1997

Leahey A. Graft versus host disease. In: Schwartz MW, editor. The 5 minute pediatric consult. Baltimore: Williams & Wilkins; 1997. p. 3576-57.

Leahey A. Bone marrow transplantation. In: Schwartz MW, editor. The 5 minute pediatric consult. Baltimore: Williams & Wilkins; 1997. p. 158-9.

1995

Leahey A. Acute lymphoblastic leukemia. In: Sinniah D, D'Angio G, editors. Atlas of Pediatric Oncology. London: Arnold; 1995. p. 10-18.

Leahey A. Chronic myeloid leukemia and myelodysplasia. In: Sinniah D, D'Angio G, editors. Atlas of Pediatric Oncology. London: Arnold; 1995. p. 26-30.

Leahey A. Acute myeloid leukemia. In: Sinniah D, D'Angio G, editors. Atlas of Pediatric Oncology. London: Arnold; 1995. p. 19-25.

Leahey A. Mediastinal mass. In: Schwartz MW, editor. Clinical handbook of pediatrics. Baltimore: Williams & Wilkins; 1995.

Editorial and Academic Positions

Editorial positions

2006-present, Reviewer, Pediatric Blood and Cancer
1995-present, Associate Editor, Atlas of Pediatric Oncology

Academic positions

2000-present, Pediatric Oncology Protocol Review Committee