Christopher E. Mascio, MD

Christopher E. Mascio, MD
Christopher E. Mascio, MD, is an attending surgeon in the Cardiac Center at Children’s Hospital of Philadelphia. Dr. Mascio performs the full range of reconstructive congenital operations, as well as cardiothoracic transplantation.

Areas of Expertise: Neonatal reconstructive surgery including Stage 1 Norwood, arterial switch, truncus arteriosus, interrupted aortic arch, Fontan and bidirectional Glenn, Tetralogy of Fallot, AV canal, Pulmonary atresia with VSD and MAPCAs, Heart, lung, and heart/lung transplantation, Ventricular assist devices, Valve repair and valve replacement, Tracheal rings
Locations: Main Campus

Education and Training

Medical School

MD - Loyola University Chicago, Stritch School of Medicine, Chicago, IL

Internship

General Surgery - Loyola University, Maywood, IL

Residency

General Surgery - Loyola University, Maywood, IL
Administrative Chief Residency in Surgery - Loyola University Chicago, Maywood, IL

Fellowship

Pediatric Cardiothoracic Surgery - The Children's Hospital of Philadelphia, Philadelphia, PA
Research Fellow, Cardiothoracic Surgery - University of Iowa, Iowa City, IA
Clinical Fellow, Cardiothoracic Surgery - University of Iowa, Iowa City, IA

Board Certification

American Board of Surgery-General Surgery
Cardiothoracic Surgery
Congenital Heart Surgery

Titles and Academic Titles

Attending Surgeon

Alice Langdon Warner Endowed Chair in Pediatric Cardiothoracic Surgery

Assistant Professor of Clinical Surgery, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2019

Zielonka B, Snarr BS, Liu MY, Zhang X, Mascio CE, Fuller S, Gaynor JW, Spray TL, Rychik J. Resource utilization for prenatally diagnosed single-ventricle cardiac defects: A Philadelphia fetus-to-Fontan cohort study. J Am Heart Assoc. 2019;8(11):e011284.

2017

Deng LX, Gleason LP, Khan AM, Drajpuch D, Fuller S, Goldberg LA, Mascio CE, Partington SL, Tobin L, Kim YY, Kovacs AH. Advance Care Planning in Adults with Congenital Heart Disease: A Patient Priority. Int J Cardiol. 2017 Mar 15;231:105-109. doi: 10.1016/j.ijcard.2016.12.185. PMID: 28096041

Herrmann JL, Irons ML, Mascio CE, Rychik J, Spray TL, Gaynor JW, Pogoriler JE. Congenital pulmonary lymphangiectasia and early mortality after stage 1 reconstruction procedures. Cardiol Young. 2017 Mar 13:1-5. doi: 10.1017/S1047951117000348. [Epub ahead of print] PMID: 28287055

Sharp MK, Gregg M, Brock G, Nair N, Sahetya S, Austin EH 3rd, Mascio C, Slaughter MD, Pantalos GM. Comparison of Blood Viscoelasticity in Pediatric and Adult Cardiac Patients. Cardiovasc Eng Technol. 2017 Mar 10. doi: 10.1007/s13239-017-0300-7. [Epub ahead of print] PMID: 28283942

Elias MD, Glatz AC, O'Connor MJ, Schachtner S, Ravishankar C, Mascio CE, Cohen MS. Prevalence and Risk Factors for Pericardial Effusions Requiring Readmission After Pediatric Cardiac Surgery. Pediatr Cardiol. 2017 Mar;38(3):484-494. doi: 10.1007/s00246-016-1540-2. PMID: 27900408

Fogel MA, Li C, Elci OU, Pawlowski T, Schwab PJ, Wilson F, Nicolson SC, Montenegro LM, Diaz L, Spray TL, Gaynor JW, Fuller S, Mascio C, Keller MS, Harris MA, Whitehead KK, Bethel J, Vossough A, Licht DJ. Neurological Injury and Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction. Circulation. 2017 Feb 14;135(7):671-682. doi: 10.1161/CIRCULATIONAHA.116.021724. PMID: 28031423

2016

Herrmann JL, Goldberg LA, Khan AM, Partington SL, Brothers JA, Mascio CE, Spray TL, Kim YY, Fuller S. A Comparison of Perioperative Management of Anomalous Aortic Origin of a Coronary Artery Between an Adult and Pediatric Cardiac Center. World J Pediatr Congenit Heart Surg. 2016 Nov;7(6):721-726. PMID: 27834765

Spray TL, Fuller S, Mascio CE, Gaynor JW. Cardiovascular Surgery at The Children's Hospital of Philadelphia. Semin Thorac Cardiovasc Surg. 2016 Autumn;28(3):626-633. doi: 10.1053/j.semtcvs.2016.11.003. PMID: 28285667

Yuerek M, Rossano JW, Mascio CE, Shaddy RE. Postoperative management of heart failure in pediatric patients. [Review] Expert Reviews in Cardiovascular Therapy 14(2):201-215, Feb. 2016 (Epub Dec. 1, 2016).  PMID: 26560361

Patel JK, Glatz AC, Ghosh RM, Jones SM, Ravishankar C, Mascio C, Cohen MS.  Accuracy of transesophageal echocardiography in the identification of postoperative intramural ventricular septal defects.  Journal of Thoracic & Cardiovascular Surgery (3):688-695, Sept. 2016.  PMID: 27183884

Gaies M, Pasquali SK, Donohue JE, Dimick JB, Limbach S, Burnham N, Ravishankar C, Ohye RG, Gaynor JW, Mascio CE.  Seminal postoperative complications and mode of death after pediatric cardiac surgical procedures. Annals of Thoracic Surgery 102(2):628-635, Aug. 2016 (Epub May 4, 2016).  PMID: 27154145

Misfeldt AM, Kirsch RE, Goldberg DJ, Mascio CE, Naim MY, Zhang X, Mott AR, Ravishankar C, Rossano JW.  Outcomes of single-ventricle patients supported with extracorporeal membrane oxygenation.  Pediatric Critical Care Medicine 17(3):194-202, Mar. 2016.  PMID: 26808622

2015

Deng LX, Khan AM, Drajpuch D, Fuller S, Ludmir J, Mascio CE, Partington SL, Qadeer A, Tobin L, Kovacs AH, Kim YY.  Prevalence and correlates of post-traumatic stress disorder in adults with congenital heart disease. American Journal of Cardiology 117(5):853-857, Mar. 1, 2016 (Epub Dec. 13, 2015).  PMID: 26803381

Mascio CE, Spray TL. Distal dunk for right ventricle to pulmonary artery shunt in stage 1 palliation. Annals of Thoracic Surgery 100(6):2381-2382, Dec. 2015.  PMID: 26652546

Fuller SM, He X, Jacobs JP, Pasquali SK, Gaynor JW, Mascio CE, Hill KD, Jacobs ML, Kim YY.  Estimating mortality risk for adult congenital heart surgery: An analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database.  Annals of Thoracic Surgery 100(5):1728-1735, Nov. 2015 (Epub Sept. 25, 2015).  PMID: 26411754

Patel JK, Glatz AC, Ghosh RM, Jones SM, Natarajan S, Ravishankar C, Mascio CE, Spray TL, Cohen MS.  Intramural ventricular septal defect is a distinct clinical entity associated with postoperative morbidity in children after repair of conotruncal anomalies.  Circulation 132(15):1387-1394, Oct. 13, 2015 (Epub Aug. 5, 2015). PMID: 26246174

O'Connor MJ, Keeshan BC, Lin KY, Monos D, Lind C, Paridon SM, Mascio CE, Shaddy RE, Rossano JW. Changes in the methodology of pre-heart transplant human leukocyte antibody assessment: An analysis of the United Network for Organ Sharing Database. Clinical Transplantation 29(9):842-850, Sept. 2015 (Epub July 14, 2015).  PMID: 26172275

Abstracts

2016

Shamszad P, Costarino AT, Rychik J, Mascio CE, Rome JJ, Shaddy RE, Rossano JW. Drivers of hospital resource utilization in infants with hypoplastic left Heart syndrome undergoing surgical stage I palliation. European Heart Journal 37(Suppl 1):961, 2016.

Elias MD, Glatz AC, O'Connor MJ, Schachtner S, Ravishankar C, Mascio CE, Cohen MS. Prevalence and risk factors for pericardial effusion requiring readmission after pediatric cardiac surgery. Journal of the American College of Cardiology 67(13 Suppl 1):979, 2016.

Wittlieb-Weber CA, Rossano JW, Weber DR, Lin KY, Ravishankar C, Mascio CE, Shaddy RE, O'Connor MJ. Emergency department utilization by pediatric heart transplant recipients. Journal of Heart & Lung Transplantation 35(4 Suppl 1):S399-S400, 2016.

Misfeldt A, Goldberg DJ, O'Conner MJ, Shamszad P, Almond CS, Mascio CE, Lin KY, Zhang X, Rychik J, Shaddy RE, Rossano JW. Heart failure related hospitalizations in children with single ventricle heart disease: Prevalence, risk factors for mortality, and economic burden. Journal of Heart & Lung Transplantation 35(4 Suppl 1):S398, 2016.

2015

McCarthy AL, Winters ME, Bixler E, Lynch JM, Newland JJ, Busch DR, Ko T, Xiao R, Nicolson SC, Montenegro LM, Mascio CE, Fuller S, Gaynor WJ, Spray TL, Licht DJ, Naim MY. Earlier stage I operation in neonates with hypoplastic left heart syndrome is not associated with worse short-term outcomes. Circulation 132(Suppl 3): 2015.

Nandi D, O'Connor M, Lin K, Paridon S, Ravishankar C, Mascio C, Shaddy R, Rossano J. Modeling the clinical and cost-effectiveness of dobutamine stress echocardiography with confirmatory coronary angiography for the diagnosis of pediatric cardiac allograft vasculopathy. American Journal of Transplantation 15(Suppl 3):2015.

Deng LX, Gleason LP, Khan AM, Drajpuch D, Fuller S, Goldberg LA, Mascio CE, Partington SL, Tobin L, Kim YY, Kovacs A. Communication preferences for advance care planning in adults with congenital heart disease. Journal of the American College of Cardiology 65(10 Suppl 1): A549, 2015.

Deng L, Khan AM, Drajpuch D, Fuller S, Gleason LP, Ludmir J, Mascio CE, Partington SL, Tobin L, Kim YY, Kovacs A. Anxiety is more common than depression in adults with congenital heart disease. Journal of the American College of Cardiology 65(10 Suppl 1):A547, 2015.

Wilder TJ, Blackstone E, Rajeswaran J, Caldarone C, Gruber PJ, Alsoufi B, Jaquiss R, Tchervenkov CI, Jaggers J, Si M-S, Mascio C, Pizarro C, Overman D, Hickey E. Trends in right ventricular dysfunction and tricuspid regurgitation after single ventricle palliation of hypoplastic left heart syndrome and their differential impact on survival. Journal of the American College of Cardiology 65(10 Suppl 1):A504, 2015.

Books

2016

Mascio CE, Gaynor JW. Neuromonitoring and neurodevelopmental outcomes in congenital heart surgery. Chap. 111 in Selke FW, del Nido PJ, Swanson SJ (eds.): Sabiston and Spencer’s Surgery of the Chest, 9th Edition. Philadelphia: Elsevier, 2016, 2002-2010.

2014

Mascio CE, Austin EH. Vascular rings, slings and other arch anomalies. Chap. 78 in Kaiser LR, Kron IL, Spray TL (eds.): Mastery of Cardiothoracic Surgery, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2014, 797-815.

2011

Mascio CE, Austin EH. Cerebral protection. Chap. 347 in Franco KL, Thourani VH (eds.): Cardiothoracic Surgery Review. Philadelphia: Lippincott Williams & Wilkins, 2011, 1513-1514.

2009

Mascio CE, Austin EH. Pulmonary atresia with intact ventricular septum. Chap.118 in Selke FW, del Nido PJ, Swanson SJ (eds.): Sabiston & Spencer Surgery of the Chest, 8th Edition. Philadelphia: Elsevier, 2009, 1865-1876.

2000

Mascio C, Arensman R. Inflammatory bowel disease. Chap. in Arensman RM, Bambini DA, Almond PS (eds.): Handbook of Pediatric Surgery. Austin, TX: Landes Bioscience, 2000, 402-407.

Posters and Presentations

Lectures by Invitation
2017

“Mechanical Circulatory Support in the Pediatric/Congenital Heart Patient.”  Indiana University Division of Cardiothoracic Surgery, Indianapolis, IN, Feb. 2017

“D-Transposition of the Great Arteries.”  Cardiology 2017, Orlando, FL, Feb. 2017

“HeartWare BiVAD: Trials and Tribulations.”  Cardiology 2017, Orlando, FL, Feb. 2017

“The “Single Ventricle” Heart: Staged Palliation from First Stage Through Fontan.”  Cardiology 2017, Orlando, FL, Feb. 2017

“Update on Mechanical Circulatory Support in the Pediatric and Congenital Heart Patient.”  Cardiology 2017, Orlando, FL, Feb. 2017

“Ventricular Assist after Fontan: Devices & Push v. Pull.”  Cardiology 2017, Orlando, FL, Feb. 2017

“Advanced HeartWare Techniques: Single Ventricle, Atrial Cannulation, & AV Valve Excision.”  The Society of Thoracic Surgeons 53rd Annual Meeting, Houston, TX, Jan. 2017   

Moderator, “Congenital Cardiac Surgery Melange.”  The Society of Thoracic Surgeons 53rd Annual Meeting, Houston, TX, Jan. 2017  

Moderator, “Adult Congenital.”  The Society of Thoracic Surgeons 53rd Annual Meeting, Houston, TX, Jan. 2017 

Moderator, “Learning From My Mistakes: A Case I Wish I Could Do Over.”  The Society of Thoracic Surgeons 53rd Annual Meeting, Houston, TX, Jan. 2017

2016

“Device Overview:  The HeartWare HVAD.”  University of Virginia Heart Failure/Transplant, Charlottesville, VA, Nov. 2016

“Operative Strategies: The Limits of Cerebral Perfusion and Total Circulatory Arrest.”  5th Annual Cardiac Neurodevelopmental Symposium, Philadelphia, PA, June 2016

2015

“Ventricular Assist Devices in the Pediatric Population.”  Pennsylvania State Perfusion Society Fall Meeting, King of Prussia, PA, Oct. 2015

“Open Heart Surgery, CPB, Circulatory Arrest, and Other Mysteries of the OR.”  Cardiology 2015, Scottsdale, AZ, Feb. 2015

“Device Overview: The HeartWare LVAD.”  Cardiology 2015, Scottsdale, AZ, Feb. 2015

“HLHS-Surgery.”  Cardiology 2015, Scottsdale, AZ, Feb. 2015

“Individualizing Surgical Strategies for Repair of Tetralogy of Fallot: Sparing the Pulmonary Valve and Other Techniques.”  Cardiology 2015, Scottsdale, AZ, Feb. 2015

“Surgical Management of Aortic Disease: The Congenital Heart Disease Focused Surgeon.”  Cardiology 2015, Scottsdale, AZ, Feb. 2015

Awards and Honors

2008-2009, Better Care Award, Norton Healthcare/Kosair Children's Hospital

2008, Better Care Award, Norton Healthcare/Kosair Children's Hospital (as chosen by parents/guardians of patients)

2001, Alpha Omega Alpha

2000, Resident of the Year, Loyola University/Stritch School of Medicine (as chosen by medical students)

2000, Jack R. Pickleman, MD Resident Teaching Award, Loyola University/Stritch School of Medicine

1998, Intern of the Year, Loyola University/Stritch School of Medicine (as chosen by attending physicians)

1993, Cum Laude Graduate, University of Notre Dame

1992, Alpha Epsilon Delta Premedical Honor Society

Editorial and Academic Positions

Editorial positions

Ad-hoc Reviewer

2007-present, Journal of Cardiac Surgery

2007-present, Journal of Thoracic & Cardiovascular Surgery

2009-present, International Journal of Pediatrics

2010-present, ASAIO Journal

2011-present, Circulation

2012-present, Cardiology in the Young

2012-present, World Journal for Pediatric and Congenital Heart Surgery

Leadership and Memberships

Memberships in Professional Organizations

National/International

2012-present, Congenital Heart Surgeons' Society

2012-present, Society of Thoracic Surgeons Patient Safety Workforce

2010-present, International Society for Pediatric Mechanical Cardiopulmonary Support

2007-present, Society of Thoracic Surgeons

2006-present, American Heart Association

2006-present, Associate Fellow, American College of Surgeons