Jennifer McGuire, MD, MSCE

Papers

2022

Fink EL, Robertson CL, Wainwright MS, Roa JD, Lovett ME, … McGuire JL, et al; Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID) Investigators. : Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C. Pediatric Neurology 128: 33-44, Mar 2022.

M Jacobwitz, E Favilla, A Patel, TM Giglia, K Tiang, C Ravishankar, JW Gaynor, DJ Licht, JL McGuire*, LA Beslow* (* co-last authors): Neurologic Complications of Infective Endocarditis in Children. Cardiology in the Young Pub ahead of print, May 2022 Notes: doi: 10.1017/S1047951122001159.

D Guez-Barber, SK Swami, JB Harrison, JL McGuire: Differentiating Bell's palsy from Lyme-Related Facial Palsy. Pediatrics 149(1): e2021053992, June 2022.

G Chang, M Blackstone, JL McGuire: Race and the emergency department management of febrile seizures. Medicine 101(42): e31315, October 2022.

SN Brosius, W Otto, A Waldman, M Russo, J McGuire: Clinical Reasoning: A 12-Month-Old Male With Staring Episodes, Ataxia, and Right-Sided Weakness. Neurology 99 (18): 805-810, Nov 2022.

2021

AM Alcamo, JL McGuire, HK Kanthimathinathan, JD Roa, EL Fink (*co-first authors): Worldwide Epidemiology of Neuro-COVID in Children: Lessons for the Next Pandemic. Current Opinion in Pediatrics 33(6): 580-590, Dec 2021

WR Otto, WZ Paden, M Connors, T Joerger, A Buzi, M Rizzi, J Huh, PB Storm, G Heuer, B Kennedy, J McGuire, S Swami, SS Lang: Suppurative intracranial complications of pediatric sinusitis: a single-center experience. J Pediatric Infect Dis Soc 10(3): 309-316, Apr 2021.

C Del Valle Mojica, J Montoya, J McGuire, KL Plama, KV Shekdar, R McLeod, DG Contopoulos-Ioannidis: Diagnosis of Congenital Toxoplasmosis with Macrocephaly in Dizygotic Twins after Incidental Detection of Leukocoria: A Case Report. J Pediatr 236: 301-306, Sept 2021.

AE Becker, K Chiotos, JL McGuire, BB Bruins, AM Alcamo: Intracranial Hypertension in Multisystem Inflammatory Syndrome in Children. J Pediatr 233: 263-267, June 2021.

S Frankl, SE Coffin, JBB Harrison, SK Swami, JL McGuire: Influenza-Associated Neurologic Complications in Hospitalized Children. J Pediatr 239: 24-31e1, December 2021.

2019

McGuire JL, Tuite N, Swami S, Avery RA: Assessment of the Diagnostic Yield of Non-Culture CSF Infection Testing in Children. JAMA Network Open 2(7): e197307, July 2019.

Matesanz S*, McGuire JL*, Hopkins S, *co-first authors: Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center. J Pediatr 215: 272-276.e1, December 2019.

2018

Gofshteyn, J; Shaw, P.A.; Teachey D.T.; Grupp, S; Maude, S; Banwell, B; Chen F; Lacey, S.F.; Melenhorst, J.J.; Edmonson M.J.; Panzer J; Barrett D.M. and McGuire, JL: Neurotoxicity after CTL-19 in a Pediatric and Young Adult Cohort. Annals of Neurology [Epub ahead of print], Sep 2018 Notes: doi: 10.1002/ana.25315.

2016

McGuire JL, Gill AJ, Douglas SD, Kolson DL; CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Group. The complement system, neuronal injury, and cognitive function in horizontally-acquired HIV-infected youth. J Neurovirol. 2016 Dec;22(6):823-830. Epub 2016 Jun 6.

2015

JL McGuire, J Kempen, R Localio, JE Ellenberg, SD Douglas: Immune Markers Predictive of Neuropsychiatric Symptoms in HIV Infected Youth. Clinical and Vaccine Immunology 22(1): 27-36, 2015.

JL McGuire, A Gill, SD Douglas, D Kolson: Central and Peripheral Markers of Neurodegeneration and Monocyte Activation in HIV-Associated Neurocognitive Disorders. J Neurovirology 21(4): 439-48, 2015 Notes: Epub ahead of print 3/17/15.

AJ Lautz, B Jenssen, JL McGuire, JA St Geme: Diagnostic Dilemmas and Clinical Reasoning: A 33-month old with fever and altered mental status. Pediatrics 135(1): 120-125, 2015 Notes: Epub ahead of print 12/8/14.

2014

JL McGuire, JS Barrett, H Vezina, S Spitsin, SD Douglas: Adjuvant Therapies for HIV-Associated Neurocognitive Disorders. Annals of Clinical and Translational Neurology 1(11): 938-952, 2014.

NS Abend, D Bearden, I Helbig, J McGuire, S Narula, JA Panzer, A Topjian, DJ Dlugos: Status Epilepticus and Refractory Status Epilepticus Management. Seminars in Pediatric Neurology 21: 263-274, 2014.

2013

JS Barrett, JL McGuire, H Vezina, S Spitsin, SD Douglas: PET measurement of receptor occupancy as a tool to guide dose selection in neuropharmacology: Are we asking the right questions? Journal of Clinical Psychopharmacology 33(6): 725-728, 2013.

McGuire JL, Douglas SD: Neuroimmune Dysregulation in HIV-Associated Neurocognitive Disorders. Psychiatric Annals 43(5): 212-216, 2013.

McGuire JL, Goodkin K, Douglas SD: The Neuropathogenesis of Central Nervous System HIV Infection. Psychiatric Annals 43(5): 217-222, 2013.

2012

JL McGuire, J Zorc, D Licht RL Hodinka, SS Shah: Herpes Simplex Testing in Neonates and Young Infants in the Emergency Department. Pediatric Emergency Care 28(10): 949-955, 2012.

2011

JL McGuire, V Fridman, I Koralnik, D Jacobs: Progressive Multifocal Leukoencephalopathy in a Patient with an Isolated CD8+ T Cell Deficiency. J Neurovirol 17: 500-503, 2011.

2008

JL McGuire, LA Beslow, RS Finkel, RA Zimmerman, FA Henretig: A Teenager with Focal Weakness. Pediatric Emergency Care 24(12): 875-879, 2008.

2001

WR Hale, J McGuire, ID Sand, KK Dohrer: Heat Setting of Stretched and Microvoided PE/CaCO3 Films. J. of Applied Polymer Science  82(10): 2454-2471, 2001.

2000

AA Link, T Kino, JA Worth, JL McGuire, ML Crane, GP Chrousos, RL Wilder, and IJ Elenkov: Ligand-Activation of the Adenosine A2a Receptors Inhibits IL-12 Production by Human Monocytes  J. Immunology 164: 436-442, 2000.

Abstracts

2020

JL McGuire, R Brown, R Datta, G Fadda, N Tuite, J Harrison, SD Douglas, B Banwell: Impaired Cognition and Reduced Brain Volumes in Youth with Behaviorally Acquired HIV. Conference on Retroviruses and Opportunistic Infections (CROI) annual meeting, virtual meeting (due to COVID pandemic) March 2020.

2019

E Favilla, M Jacobwitz, K Tiang, D Licht, T Giglia, LA Beslow*, JL McGuire*, *co-senior authors: Neurologic Sequelae of Infective Endocarditis in Children. American Academy of Neurology annual meeting, Philadelphia, PA May 2019.

S Frankl, SE Coffin, SK Swami, JL McGuire: Influenza-related neurologic complications in hospitalized children with underlying neurologic disorders. ID Week, Washington DC October 2019.

Books

2022

Editors: R Tenney Soeiro, E Pete Devon: Netter's Pediatrics. Elsevier. Neurology section editor: JL McGuire (eds.). Page: 643-711, March 2022.

Chapters

2022

GS Porcari, JL McGuire, SW Yum: Neuromuscular Disorders (Chapter 116)  Netter Pediatrics - 2nd edition. R Tenney Soeiro, E Pete Devon (eds.). Elsevier, Page: 690-697, March 2022.

V Dhawan, JL McGuire, K Busl: Emergency Neurologic Life Support: Meningitis and Encephalitis Module V 5.0. Neurocritical Care Society Publishing. G Lopez, S Peacock, and A Aysenne (eds.). March 2022.

2021

JL McGuire, M DiGiovine: Chapter 19: Neurology. The Philadelphia Guide: Inpatient Pediatrics, 3rd Edition.  S Shah, M Catallozzi, G Frank, JM Ronan (eds.). McGraw-Hill Medical, Oct 2021.

2020

JL McGuire: Chapter 10: Adenoviruses. Clinical Neurovirology, 2nd Edition. Avindra Nath and Joseph R. Berger (eds.). CRC Press, Page: 141-152, Apr 2020.

2018

JL McGuire: Chapter 20: Encephalitis. Pediatric Infectious Diseases: Essentials for Practice. S Shah, AR Kemper, AJ Ratner (eds.). McGraw-Hill Medical, November 2018.

2015

JL McGuire: What are the Clinical Features of Infant Botulism? How is it Treated? (chapter 26). Curbside Consultation in Pediatric Neurology: 49 Clinical Questions. DJ Licht, N Ryan (eds.). SLACK Incorporated, Thorofare, New Jersey, Page: 123-126, 2015.

JL McGuire: What are the Causes of Guillain-Barre Syndrome, How Often Does it Occur, and How is it Treated? (chapter 32). Curbside Consultation in Pediatric Neurology: 49 Clinical Questions. DJ Licht, N Ryan (eds.). SLACK Incorporated, Thorofare, New Jersey, Page: 157-162, 2015.

2013

JL McGuire and AM Greene: Central Nervous System Infections (Chapter 16). Pediatric Neurocritical Care. NS Abend and M Helfaer (eds.). Demos, New York, Page: 267-336, 2013.

JL McGuire: Mycoplasma Encephalitis (chapter 8). Symptom-Based Diagnosis in Pediatrics. SS Shah, S Ludwig (eds.). McGraw-Hill Professional, New York, Page: 208-211, 2013.

2011

JL McGuire  : Neuromuscular Disorders (Chapter 81). Netter's Pediatrics. Florin T. and Ludwig S. (eds.). Elsevier, Philadelphia, Page: 508-515, 2011.

Posters and Presentations

2022

C Diorio, R Shraim, RM Myers, R Aplenc, B Banwell, H Bassiri, C Burudpakdee, EM Behrens, S Canna, F Chen, AM DiNofia, S Gill, VE Gonzalez, MP Lambert, AB Leahy, BL Levine, RB Lindell, SL Maude, JL McGuire, H Newman, J Perrazelli, AE Seif, SF Lacey, CH June, D Barrett, SA Grupp, DT Teachey: Comprehensive Proteomic Profiling to Identify Biomarkers and Therapeutic Targets for Immune Effector Cell Associated Neurotoxicity (ICANS) after Treatment with Chimeric Antigen Receptor T Cells. International Society of Paediatric Oncology (SIOP) annual meeting, Barcelona, Spain September 2022 Notes: Oral Presentation.

2021

L Miyares, S Swami, JL McGuire: The Diagnostic Value of Cerebrospinal Fluid Lyme Testing in Children. Pediatric Academic Societies (PAS) annual meeting, virtual May 2021 Notes: platform presentation.

2020

DG Barber, S Swami, JB Harrison, and JL McGuire: The Natural History of Lyme-Related Facial Nerve Palsy and Bells Palsy, and Effects of Steroid Use in Children. Pediatric Academic Societies (PAS) annual meeting, Philadelphia PA May 2020 Notes: Oral Poster Symposia presentation.

G Chang, M Blackstone, and JL McGuire: Race-based differences in the emergency department management of febrile seizures. Pediatric Academic Societies (PAS) annual meeting, Philadelphia PA May 2020 Notes: platform presentation.

2019

S Frankl, SE Coffin, SK Swami, and JL McGuire.: Influenza-Related Neurologic Complications in Hospitalized Children. American Academy of Neurology annual meeting, Philadelphia, PA May 2019 Notes: platform presentation.

Invited Lectures

2022

JL McGuire. "Effects of Systemic Inflammation on the Developing Brain", Children's Hospital of Philadelphia 4th annual Immune Dysregulation Symposium, May 2022, Philadelphia, PA.

JL McGuire. "Autoimmune Encephalitis", Neuroimmune Disorders in Pediatrics, CHOP Talks CME Webinars and Virtual Conferences Lecturer, Children's Hospital of Philadelphia, April 2022.

JL McGuire. "Autoimmune Encephalitis Updates", Salzburg Medical Seminars (Open Medical Institute), Child Neurology Seminar Lecturer, Salzburg, Austria, February 2022.

JL McGuire. "NeuroID cases", Salzburg Medical Seminars (Open Medical Institute), Child Neurology Seminar Lecturer, Salzburg, Austria, February 2022.

JL McGuire. "Neurologic Manifestations of acute COVID-19 and Multisystem Inflammatory Syndrome of Childhood (MIS-C)", Salzburg Medical Seminars (Open Medical Institute), Child Neurology Seminar Lecturer, Salzburg, Austria, February 2022.

JL McGuire. "How to present a case (effectively!)", Salzburg Medical Seminars (Open Medical Institute), Child Neurology Seminar Lecturer, Salzburg, Austria, February 2022.

2021

JL McGuire. "HIV, Youth and the Brain", Yale Neurology Grand Rounds, December 2021, New Haven, CT (presented virtually)

2020

JL McGuire. "Brain Structure and Cognition in Adolescents with HIV", Philadelphia FIGHT Grand Rounds, Feb 2020, Philadelphia, PA

2019

JL McGuire. "Infectious Etiologies of Acute Flaccid Myelitis: What We Do and Don't Know", Philadelphia Department of Health, AFM Seminar 7/23/19, Philadelphia, PA