Lisa M. Montenegro, MD

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Lisa M. Montenegro, MD, is a board-certified Attending Anesthesiologist in the Division of Cardiothoracic Anesthesiology at Children’s Hospital of Philadelphia.

Areas of Expertise: Clinical investigation, ICU sedation|, Medical ethics, Resident/fellowship training and continuing medical education
Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - University of Medicine and Dentistry of New Jersey, Newark, NJ

Internship

General Surgery - The Saint Francis Hospital and Medical Center, Hartford, CT

Residency

Anesthesiology - Hospital of the University of Pennsylvania, Philadelphia, PA
Anesthesiology - University of Connecticut Heath Center, Hartford, CT
General Surgery - University of Connecticut Heath Center, Hartford, CT

Fellowship

Pediatric Anesthesia, Pediatric Cardiac Anesthesia, Pediatric and Cardiac Critical Care Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Anesthesiology

Titles and Academic Titles

Attending Anesthesiologist

Co-medical Director, Cardiac Preparation and Recovery Unit

Assistant Professor of Clinical Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2016

Downing TE, Allen KY, Glatz AC, Rogers LS, Ravishankar C, Rychik J, Fuller S, Montenegro LM, Steven JM, Spray TL, Nicolson SC, Gaynor JW, Goldberg DJ.: Long-term survival after the Fontan operation: Twenty years of experience at a single center. Annals of Thoracic Surgery 2016.

Arnaoutakis GJ, Blitzer D, Fuller S, Eckhauser AW, Montenegro LM, Rossano JW, Gaynor, JW.: Mechanical circulatory support as a bridge to transplantation for the failing single ventricle. Annals of Thoracic Surgery 2016.

2014

Jain V, Buckley EM, Licht DJ, Lynch JM, Schwab PJ, Naim MY, Lavin NA, Nicolson SC, Montenegro LM, Yodh AG, Wehrli FW : Cerebral oxygen metabolism in neonates with congenital heart disease quantified by MRI and optics. J Cereb Blood Flow Metab 34(3): 380-8, March 2014.

Jain, Varsha. Buckley, Erin M. Licht, Daniel J. Lynch, Jennifer M. Schwab, Peter J. Naim, Maryam Y. Lavin, Natasha A. Nicolson, Susan C. Montenegro, Lisa M. Yodh, Arjun G. Wehrli, Felix W.: Cerebral oxygen metabolism in neonates with congenital heart disease quantified by MRI and optics. Journal of Cerebral Blood Flow & Metabolism 34(3): 380-8, Mar 2014.

Goff DA, Shera DM, Tang S, Lavin NA, Durning SM, Nicolson SC, Montenegro LM, Rome JJ, Gaynor JW, Spray TL, Vossough A, Licht DJ: Risk factors for preoperative periventricular leukomalacia in term neonates with hypoplastic left heart syndrome are patient related. J Thorac Cardiovasc Surg 147(4): 1312-8, April 2014.

Goff, Donna A. Shera, David M. Tang, Stephen. Lavin, Natasha A. Durning, Susan M. Nicolson, Susan C. Montenegro, Lisa M. Rome, Jonathan J. Gaynor, J William. Spray, Thomas L. Vossough, Arastoo. Licht, Daniel J.: Risk factors for preoperative periventricular leukomalacia in term neonates with hypoplastic left heart syndrome are patient related. Journal of Thoracic & Cardiovascular Surgery 147(4): 1312-8, Apr 2014.

Rossano JW, Goldberg DJ, Fuller S, Ravishankar C, Montenegro LM, Gaynor JW: Successful use of the total artificial heart in the failing Fontan circulation. Ann Thorac Surg. Elsevier Inc. 97(4): 1438-40, Apr 2014.

Rossano JW; Goldberg DJ; Fuller S; Ravishankar C; Montenegro LM; Gaynor JW.FA Rossano, Joseph W; Goldberg, David J; Fuller, Stephanie; Ravishankar, Chitra; Montenegro, Lisa M; Gaynor, J William.: Successful use of the total artificial heart in the failing Fontan circulation. Annals of Thoracic Surgery 94(4): 1438-40, Apr 2014.

Rossano, Joseph W. Goldberg, David J. Fuller, Stephanie. Ravishankar, Chitra. Montenegro, Lisa M. Gaynor, J William.: Successful use of the total artificial heart in the failing Fontan circulation. Annals of Thoracic Surgery 97(4): 1438-40, Apr 2014.

Fogel MA, Li C, Wilson F, Pawlowski T, Nicolson SC, Montenegro LM, Diaz Berenstein L, Spray TL, Gaynor JW, Fuller S, Keller MS, Harris MA, Whitehead KK, Clancy R, Elci O, Bethel J, Vossough A, Licht DJ: Relationship of cerebral blood flow to aortic-to-pulmonary collateral/shunt flow in single ventricles. Heart. BMJ Publishing Group Limited, 101(16): 307-11, June 2014.

Fogel MA, Pawlowski T, Schwab PJ, Nicolson SC, Montenegro LM, Berenstein LD, Spray TL, Gaynor JW, Fuller S, Keller MS, Harris MA, Whitehead KK, Vossough A, Licht DJ: Brain magnetic resonance immediately before surgery in single ventricles and surgical postponement. Ann Thorac Surg 98(5): 1693-8, November 2014.

Lynch JM, Buckley EM, Schwab PJ, McCarthy AL, Winters ME, Busch DR, Xiao R, Goff DA, Nicolson SC, Montenegro LM, Fuller S, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ: Time to surgery and preoperative cerebral hemodynamics predict postoperative white matter injury in neonates with hypoplastic left heart syndrome. J Thorac Cardiovasc Surg. Published by Elsevier Inc. 148(5): 2181-8, November 2014.

2013

Buckley, Erin M. Lynch, Jennifer M. Goff, Donna A. Schwab, Peter J. Baker, Wesley B. Durduran, Turgut. Busch, David R. Nicolson, Susan C. Montenegro, Lisa M. Naim, Maryam Y. Xiao, Rui. Spray, Thomas L. Yodh, A G. Gaynor, J William. Licht, Daniel J.: Early postoperative changes in cerebral oxygen metabolism following neonatal cardiac surgery: effects of surgical duration. Journal of Thoracic & Cardiovascular Surgery 145(1): 196-203, 205.e1; discussion 203-5, Jan 2013.

Buckley, Erin M. Naim, Maryam Y. Lynch, Jennifer M. Goff, Donna A. Schwab, Peter J. Diaz, Laura K. Nicolson, Susan C. Montenegro, Lisa M. Lavin, Natasha A. Durduran, Turgut. Spray, Thomas L. Gaynor, J William. Putt, Mary E. Yodh, A G. Fogel, Mark A. Licht, Daniel J.: Sodium bicarbonate causes dose-dependent increases in cerebral blood flow in infants and children with single-ventricle physiology. Pediatr Res 73(5): 668-73, May 2013.

Wellen, Shari L. Glatz, Andrew C. Gaynor, J William. Montenegro, Lisa M. Cohen, Meryl S.: Transesophageal echocardiography probe insertion failure in infants undergoing cardiac surgery. Congenital Heart Disease 8(3): 240-5, May-Jun 2013.

2012

Kaczorowski, David J. Sathanandam, Shyam. Ravishankar, Chitra. Gillespie, Matthew J. Montenegro, Lisa M. Gruber, Peter J. Spray, Thomas L. Gaynor, J William. Lin, Kimberly Y.: Coronary ostioplasty for congenital atresia of the left main coronary artery ostium. Annals of Thoracic Surgery 94(4): 1307-10, Oct 2012.

Nathan, Aruna T. Antzelevitch, Charles. Montenegro, Lisa M. Vetter, Victoria L.: Case scenario: anesthesia-related cardiac arrest in a child with Timothy syndrome. [Review] Anesthesiology 117(5): 1117-26, Nov 2012.

2011

Nathan AT, Berkowitz DH, Montenegro LM, Nicolson SC, Vetter VL, Jobes DR. Implications of Anesthesia in Children with Long QT Syndrome. Anesth Analg. 2011 Feb 23.

2010

Goldfarb SB, Gaynor JW, Fuller S, Kreindler J, Montenegro LM, Fynn-Thompson F, Visner G. Induction therapy with antithymocyte globulin before reperfusion. Ann Thorac Surg. 2010 Oct;90(4):1110-4; discussion 1114-5.

Nicolson SC, Montenegro LM, Cohen MS, O'Neill D, Calfin D, Jones LA, Jobes DR. A comparison of the efficacy and safety of chloral hydrate versus inhaled anesthesia for sedating infants and toddlers for transthoracic echocardiograms. J Am Soc Echocardiogr. 2010 Jan;23(1):38-42.

Successful support and separation from veno-venous extracorporeal membrane oxygenation support in a three month-old patient following bidirectional Glenn procedure.
Ryan LP, Montenegro LM, Bird GL, Gruber PJ. Interact Cardiovasc Thorac Surg. 2010 Jun 30.

2009

Chen J, Zimmerman RA, Jarvik GP, Nord AS, Clancy RR, Wernovsky G, Montenegro LM, Hartman DM, Nicolson SC, Spray TL, Gaynor JW, Ichord R: Perioperative stroke in infants undergoing open heart operations for congenital heart disease. Annals of Thoracic Surgery 88(3), 2009.

Licht DJ, Shera DM, Clancy RR, Wernovsky G, Montenegro LM, Nicolson SC, Zimmerman RA, Spray TL, Gaynor JW, Vossough A: Brain maturation is delayed in infants with complex congenital heart defects. Journal of Thoracic Cardiovascular Surgery 137(3): 536-537, 2009.

Petit CJ, Rome JJ, Wernovsky G, Mason SE, Shera DM, Nicolson SC, Montenegro LM, Tabbutt S, Zimmerman RA: Preoperative brain injury in transposition of the great arteries is associated with oxygenation and time to surgery, not balloon atrial septostomy. Circulation 119(5): 709-716, 2009.

2008

Marino, Bradley S. Pasquali, Sara K. Wernovsky, Gil. Pudusseri, Anita. Rychik, Jack. Montenegro, Lisa. Shera, David. Spray, Thomas L. Cohen, Meryl S.: Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adults.[Erratum appears in Congenit Heart Dis. 2008 Mar;3(2):159] Congenital Heart Disease 3(1): 39-46, Jan-Feb 2008.

Fogel, Mark A. Weinberg, Paul M. Parave, Elicia. Harris, Christine. Montenegro, Lisa. Harris, Matthew A. Concepcion, Mikael.: Deep sedation for cardiac magnetic resonance imaging: a comparison with cardiac anesthesia. Journal of Pediatrics 152(4): 534-9, 539.e1, Apr 2008.

Dorfman AT, Marino BS, Wernovsky G, Tabbutt S, Ravishankar C, Godinez RI, Priestley M, Dodds KM, Rychik J, Gruber PJ, Gaynor JW, Levy RJ, Nicolson SC, Montenegro LM, Spray TL, Dominguez TE : Critical heart disease in the neonate: presentation and outcome at a tertiary care center. Pediatric Critical Care Medicine 9(2): 193-202, 2008.

Fogel MA, Weinberg PM, Parave E, Harris C, Montenegro LM, Deep CM: Safety, efficacy and image quality in infants, children and adolescents undergoing deep The Journal of Pediatrics 152(4): 534-539, 2008.

Fogel MA, Weinberg PM, Parave E, Harris C, Montenegro LM, Deep CM: Safety, efficacy and image quality in infants, children and adolescents undergoing deep sedation for cardiac magnetic resonance: a comparison with cardiac anesthesia. The Journal of Pediatrics 152(4): 534-539, 2008.

Fogel MA, Weinberg PM, Parave E, Harris C, Montenegro LM, Harris MA, Concepcion M : Deep sedation for cardiac magnetic resonance imaging: A comparison with cardiac anesthesia [see comment]. Journal of Pediatrics 152(4): 534-539, 2008.

Glatz AC, Gaynor JW, Rhodes LA, Rychik J, Tanel RE, Vetter VL, Kaltman JR, Nicolson SC, Montenegro LM, Shah MJ : Outcome of high-risk neonates with congenital complete heart block paced in the first 24 hours after birth. Journal of Thoracic Cardiovascular Surgery 136: 767-773, 2008.

Marino BS, Pasquali SK, Wernovsky G, Rychik J, Montenegro LM, Shera D, Spray TL, Cohen MS, Pudusseri A: Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adults. Congenital Heart Disease 3(1): 39-46, 2008.

2007

Glatz, Jenifer A. Tabbutt, Sarah. Gaynor, J William. Rome, Jonathan J. Montenegro, Lisa. Spray, Thomas L. Rychik, Jack.: Hypoplastic left heart syndrome with atrial level restriction in the era of prenatal diagnosis. Annals of Thoracic Surgery 84(5): 1633-8, Nov 2007.

Glatz JA, Tabbutt S, Gaynor JW, Rome JJ, Montenegro LM, Spray TL, Rychik J.: Hypoplastic left heart syndrome with atrial level restriction in the era of prenatal diagnosis. Annals of Thoracic Surgery 84(5): 1633-1638, 2007.

2005

Gaynor JW, Nicolson SC, Jarvik GP, Wernovsky G, Montenegro LM, Burnham NB, Hartman DM, Souie A, Spray TL, Clancy RR: Increasing duration of deep hypothermic circulatory arrest is associated with an increased incidence of postoperative electroencephalographic seizures. Journal of Thoracic and Cardiovascular Surgery 130(5): 1278-1286, 2005.

Levy RJ, Stern WB, Minger KI, Montenegro LM, Ravishankar C, Rome JJ, Nicolson SC, Jobes DR: Evaluation of tissue saturation as a noninvasive measure of mixed venous saturation in children. Pediatric Critical Care Medicine [Journal Article] 6(6): 671-675, 2005.

Pastuszko P, Rome JJ, Gleason MM, Bellah RD, Montenegro LM, Gaynor JW: Hemoptysis after CardioSEAL device embolization of a venous collateral after the Fontan operation. Journal of Thoracic & Cardiovascular Surgery [Case Reports Journal Article) 129(6): 1447-1448, 2005.

2004

Galli, Kristin K. Zimmerman, Robert A. Jarvik, Gail P. Wernovsky, Gil. Kuypers, Marijn K. Clancy, Robert R. Montenegro, Lisa M. Mahle, William T. Newman, Mark F. Saunders, Ann M. Nicolson, Susan C. Spray, Thomas L. Gaynor, J William.: Periventricular leukomalacia is common after neonatal cardiac surgery.[Erratum appears in J Thorac Cardiovasc Surg. 2004 Sep;128(3):498 Note: Galli, Kristen K [corrected to Galli, Kristin K]] Journal of Thoracic & Cardiovascular Surgery 127(3): 692-704, Mar 2004.

Galli KK, Zimmerman RA, Jarvik GP, Kuypers M, Clancy RP, Montenegro LM, Mahle WT, Saunders AM, Nicolson SC, Spray TL, Gaynor WJ: Periventricular leukomalacia is common following infant heart surgery. Journal of Thoracic and Cardiovascular Surgery 127: 692-704, 2004.

Licht DJ, Wang J, Sivestre DW, Nicolson SC, Montenegro LM, Wernovsky G, Tabbutt S, Durning SM, Shera DM, Gaynor JW, Spray TL, Clancy RR, Zimmerman RA, Detre JA: Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects. Journal of Thoracic and Cardiovascular Surgery 128(6): 841-849, 2004.

2003

Gould DS, Montenegro LM, Gaynor JW, Lacy SP, Ittenbach R, Stephens P, Steven JM, Spray TL, Nicolson SC: A comparison of on-site and off-site patent ductus arteriosus ligation in premature infants. Pediatrics 112(6 ): 1298-1301. 2003.

Seifert HA, Jobes DR, TenHave T, Kimmel SE, Montenegro LM, Steven JM, Nicolson SC, Stron BL: Adverse events after protamine administration following cardiopulmonary bypass in infants and children. Anesthesia and Analgesia 97(2): 383-389, 2003.

2002

Ramamoorthy, Chandra. Tabbutt, Sarah. Kurth, C Dean. Steven, James M. Montenegro, Lisa M. Durning, Suzanne. Wernovsky, Gil. Gaynor, J William. Spray, Thomas L. Nicolson, Susan C.: Effects of inspired hypoxic and hypercapnic gas mixtures on cerebral oxygen saturation in neonates with univentricular heart defects. Anesthesiology 96(2): 283-8, Feb 2002.

Mahle, William T. Tavani, Federica. Zimmerman, Robert A. Nicolson, Susan C. Galli, Kristin K. Gaynor, J William. Clancy, Robert R. Montenegro, Lisa M. Spray, Thomas L. Chiavacci, Rosetta M. Wernovsky, Gil. Kurth, C Dean.: An MRI study of neurological injury before and after congenital heart surgery. Circulation 106(12 Suppl 1): I109-14, Sep 24 2002.

Mahle WT, Tavani F, Zimmerman RA, Nicolson SC, Galli K, Gaynor JW, Wernovsky G, Clancy RR, Montenegro LM, Spray TL, Chiavacci R, Kurth CD: An MRI study of neurological injury before and after congenital heart surgery. Circulation 106(12 suppl 1): I109-114, 2002.

Ramamoorthy C, Tabbutt S, Kurth CD, Steven JM, Montenegro LM, Durning S, Wernovsky G, Gaynor JW, Spray TL, Nicolson SC: Effects of hypoxic and hypercapnic inspired gas mixtures on cerebral oxygen saturation in neonates with hypoplastic left heart syndrome. Anesthesiology 96(2): 283-288, 2002.

2001

Kurth, C D. Steven, J L. Montenegro, L M. Watzman, H M. Gaynor, J W. Spray, T L. Nicolson, S C.: Cerebral oxygen saturation before congenital heart surgery. Annals of Thoracic Surgery 72(1): 187-92, Jul 2001.

Tabbutt, S. Ramamoorthy, C. Montenegro, L M. Durning, S M. Kurth, C D. Steven, J M. Godinez, R I. Spray, T L. Wernovsky, G. Nicolson, S C.: Impact of inspired gas mixtures on preoperative infants with hypoplastic left heart syndrome during controlled ventilation. Circulation 104(12 Suppl 1): I159-64, Sep 18 2001.

Kurth CD, Steven JM, Montenegro LM, Watzman HM, Gaynor JW, Spray TL, Nicolson SC: Cerebral oxygen saturation before congenital heart surgery. Annals of Thoracic Surgery 72: 187-192, 2001.

2000

Watzman, H M. Kurth, C D. Montenegro, L M. Rome, J. Steven, J M. Nicolson, S C.: Arterial and venous contributions to near-infrared cerebral oximetry. Anesthesiology 93(4): 947-53, Oct 2000.

Lee HR, Montenegro LM, Nicolson SC, Gaynor JW, Spray TL, Rychik J: Usefulness of intraoperative transesophageal echocardiography in predicting the degree of mitral regurgitation secondary to atrioventricular canal defect in children. American Journal of Cardiology 83: 750-753, 2000.

Tabbutt S, Ramamoorthy C, Montenegro LM, Durning SM, Kurth CD, Steven JM, Godinez GI, Spray TL, Wernovsky G, Nicolson SC: Impact of inspired gas mixtures on pre-operative infants with hypoplastic left heart syndrome (HLHS) during controlled ventilation. Circulation 102(Supplement II): 469, 2000.

Watzman HM, Kurth CD, Montenegro LM, Rome JJ, Steven JM, Nicolson SC: Arterial and venous contributions to near-infrared cerebral oximetry. Anesthesiology 93(4): 947-953, 2000.

1999

Weinstein, S. Gaynor, J W. Bridges, N D. Wernovsky, G. Montenegro, L M. Godinez, R I. Spray, T L.: Early survival of infants weighing 2.5 kilograms or less undergoing first-stage reconstruction for hypoplastic left heart syndrome. Circulation 100(19 Suppl): II167-70, Nov 9 1999.

Watzman HM, Kurth CD, Rome JJ, Nicolson SC, Steven JM, Montenegro LM: Validation of phase-modulation near-infrared spectroscopy with cerebral oxygen saturation measurements in children. Anesthesiology 89: A458, 1999.

Weinstein S, Gaynor JW, Wernovsky G, Montenegro LM, Godinez RI, Rubenstein SD, Spray TL: Survival of low birth weight in infants undergoing Stage I Norwood reconstruction for hypoplastic left heart syndrome or single ventricle physiology. Circulation 100(Supplement II): 167-170, 1999.

1998

Montenegro LM, Ward A, McGowan FX, Davis PJ: New directions in perioperative management for pediatric solid organ transplantation. Journal of Cardiothoracic Vascular Anesthesia 12(4): 457-472, 1998.

Shores J, Montenegro LM, Bridges ND: Primary vs. secondary pulmonary hypertension: Difference in pulmonary vascular responsiveness elicited with nitric oxide. Circulation 98: I186, 1998.

1991

Lapidus, G. Braddock, M. Banco, L. Montenegro, L. Hight, D. Eanniello, V.: Child pedestrian injury: a population-based collision and injury severity profile. Journal of Trauma-Injury Infection & Critical Care 31(8): 1110-5, Aug 1991.

Lapidus G, Braddock M, Banco L, Montenegro LM, Hight D, Eanniello V: Child pedestrian injury: A population-based collision and injury severity profile. The Journal of Trauma 31(8): 1110-1115, 1991.

1983

Montenegro LM, Sicard R: Cyclic AMP and norepinephrine stimulate 35S uptake by newt regeneration blastemas, in vitro. The Journal of Cell Biology (97), 479, 1983.

Books

Jobes, DR and Montenegro, LM: Complications of Massive Transfusion. Complications in Anesthesia, 2006.

Chapters

1999

Montenegro LM, Jobes DR.: Complications of massive transfusion. Complications in Anesthesiology. Atlee, J (eds.). W.B. Saunders Company, 1999.

1998

Montenegro LM, Greeley WJ: Pediatric echocardiography. Pediatric Cardiac Anesthesia. Lake, C (eds.). Appleton and Lange, Page: 51-69, 1998.

Awards and Honors

2012, Department of Anesthesia and Critical Care Chair Award (Cardiac Anesthesia)
2009, SuPEERior Person Award
2008, Department of Anesthesia and Critical Care Chair Award
2002, SuPEERior person Award

Editorial and Academic Positions

Academic and Institutional Committees

2013-present, EPIC Anesthesia Implementation SuperUser, planning and implementation
2010-present, Liaison to Transplant Team
2009-present, Co-medical Director of the Cardiac Preparation and Recovery Unit
2009-present, Liaison to Pharmacy (Cardiac Anesthesia)

Leadership and Memberships

Memberships in Professional Organizations

International

2010-present, Society for Pediatric Anesthesia
2010-present, Congenital Cardiac Anesthesia Society

National

2006-present, American Society of Anesthesiologists