Amanda Muir, MD, MTR

Papers

2024

Kennedy K, Umenemi N, Alston M, Dolinski L, Taylor LA, Bendavid A, Goh V, Whitehorn-Brown T, Albenberg LA, Cianferoni A, Muir AB: Esophageal remodeling correlates with eating behaviors in pediatric eosinophilic esophagitis. American Journal of Gastroenterology 2024 Notes: *Accepted.

Sasaki M, Hara T, Wang JX, Zhou Y, Kennedy KV, Umeweni N, Alston M, Spergel ZC, Ishikawa S, Teranishi R, Nakagawa R, Mcmillan E, Whelan KA, Karakasheva TA, Hamilton KE, Ruffner MA, Muir AB: Manuscript title Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis. Cellular and Molecular Gastroenterology and Hepatology 2024 Notes: *accepted.

Shaul E, Kennedy KV, Spergel Z, Thanawala S, Mahon M, Ryan M, Muir AB: Endoscopic and histologic utility of transnasal endoscopy in pediatric eosinophilic esophagitis. Journal of Pediatric Gastroenterology and Nutrition 2024 Notes: *accepted.

2023

Lynch KL, Benitez AJ, Godwin B, Klein J, Savant D, Wilkins BJ, Menard-Katcher C, Gluckman C, Falk GW, Muir A: The Slender Esophagus: Unrecognized Esophageal Narrowing in Eosinophilic Esophagitis. Clin Transl Gastroenterol. 14(4): e00564, Apr 2023 Notes: doi: 10.14309/ctg.0000000000000564.

Kabir MF, Jackson JL, Fuller AD, Gathuka L, Karami AL, Conde DG, Klochkova A, Mu A, Cai KQ, Klein-Szanto AJ, Muir AB, Whelan KA: Diclofenac exhibits cytotoxic activity associated with metabolic alterations and p53 induction in ESCC cell lines and decreases ESCC tumor burden in vivo. Carcinogenesis 44(2): 182-195, May 2023 Notes: doi: 10.1093/carcin/bgad019.

Karakasheva TA, Zhou Y, Xie HM, Soto GE, Johnson TD, Stoltz MA, Roach DM, Nema N, Umeweni CN, Naughton K, Dolinsky L, Pippin JA, Wells AD, Grant SFA, Ghanem L, Terry N, Muir AB, Hamilton KE: Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures. Gastro Hep Adv. 6(2): 830-842, May 2023 Notes: doi: 10.1016/j.gastha.2023.05.003. Epub 2023 May 25.

2022

Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB: CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cell Mol Gastroenterol Hepatol 13(5): 1449-1467, Jan 2022 Notes: doi: 10.1016/j.jcmgh.2022.01.018. Epub 2022 Jan 30.

Kabir M, Karami A, Cruz-Acuña R, Klochkova A, Saxena R, Mu A, Murray MG, Cruz J, Fuller A, Clevenger M, Chitrala K, Tan Y, Keith K, Madzo J, Huang H, Jelinek J, Karakasheva T, Hamilton K, Muir A, Tetreault M-P, Whelan K : Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium. Nature Communications 13(1): 2167, Apr 2022 Notes: doi: 10.1038/s41467-022-29747-x.

Spergel BL, Ruffner MA, Godwin BC, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TF, Chaiboonma K, Aceves SA, Muir AM, Spergel JM.: Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use. Ann Allergy Asthma Immunol 128(5): 589-593, May 2022 Notes: doi: 10.1016/j.anai.2022.01.019. Epub 2022 Jan 25.

Muir AB, Ackerman SJ, Zhoaxing P, Benitez AJ, Burger C, Spergel JM, Furuta GT, Rothman J, Wilkins BJ, Arnold M, Dolinsky L, Grozdanovic M, Menard-Katcher C.  : Esophageal remodeling in Eosinophilic Esophagitis:  Relationships to luminal captured biomarkers of inflammation and periostin. Journal of Allergy and Clinical Immunology 150(3): 649-656.e5, Sep 2022 Notes: doi: 10.1016/j.jaci.2022.03.022. Epub 2022 Apr 8.*Received editor's choice recognition

Klochkova A, Fuller AD, Miller R, Karami AL, Panchani SR, Natarajan S, Mu A, Jackson JL, Klein-Szanto AJ, Muir AB, Whelan KA.: A role for age-associated alterations in esophageal epithelium in eosinophilic esophagitis-associated fibrosis. Front Allergy 15(3): 983412, Dec 2022 Notes: doi: 10.3389/falgy.2022.983412. eCollection 2022.

Benitez AJ, McGar A, Kohser K, Gibbons T, Muir A, Mascarenhas M, Rossi C, Dogias F, Golden A, Kassam-Adams N, Marsac ML.: The Cellie Coping Kit for children with Eosinophilic Esophagitis: Feasibility, acceptability, and preliminary outcomes. J Child Health Care 27(3): 374-385, Jan 2023 Notes: doi: 10.1177/13674935211064126. Epub 2022 Jan 3.

2021

Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE: Colonoids From Patients With PediatricInflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation. Inflamm Bowel Dis 27(2): 256-267, Jan 2021 Notes: doi: 10.1093/ibd/izaa145.

Moore H, Wechsler J, Frost C, Whiteside E, Baldassano R, Markowitz J, Muir AB : Comorbid Diagnosis of Eosinophilic Esophagitis and Inflammatory Bowel Disease in the Pediatric Population. Journal of Pediatric Gastroenterology and Nutrition 72(3): 398-403, Mar 2021 Notes: doi: 10.1097/MPG.0000000000003002.

Benitez AJ, Tanes C, Mattei L, Hofstaedter CE, Kim DK, Gross J, Ruffner MA, Albenberg L, Spergel J, Bittinger K, Muir AB.: Effect of topical swallowed steroids on the bacterial and fungal esophageal microbiota in eosinophilic esophagitis. Allergy 76(5): 1549-1552, May 2021 Notes: doi: 10.1111/all.14602. Epub 2020 Oct 19.

Chiang AWT, Duong LD, Shoda T, Nhu QM, Ruffner M, Hara T, Aaron B, Joplin E, Manresa M, Abonia JP, Dellon E, Hirano I, Gonsalves N, Gupta SK, Furuta GT, Rothenberg ME, Lewis NE, Muir AB*, Aceves SS*, CEGIR Investigator Group: Type 2 Immunity and Age Modify Gene Expression of COVID19 Receptors in Eosinophilic Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition 72(5): 718-722, May 2021 Notes: doi: 10.1097/MPG.0000000000003032.*co-senior authorship.

Ruffner MA, Zhang Z, Maurer K, Muir AB, Cianferoni A, Sullivan KE, Spergel JM.: RNA sequencing identifies global transcriptional changes in peripheral CD4+ cells during active oesophagitis and following epicutaneous immunotherapy in eosinophilic oesophagitis Clin Transl Immunology 10(7): e1314, Jul 2021 Notes: doi: 10.1002/cti2.1314. eCollection 2021.

Thanawala SU, Beveridge CA, Muir AB, Strobel MJ, Westcott-Chavez A, Serper M, Yang YX, Lynch KL.: Hashing out current social media use in eosinophilic esophagitis. Dis Esophagus 34(11): doab059, Nov 2021 Notes: doi: 10.1093/dote/doab059.

Benitez AJ, Budhu S, Burger C, Turco R, Ballester L, Shah A, Lynch K, Fiorino K, Menard-Katcher C, Muir AB, Mamula P.: Use of the functional luminal imaging probe in pediatrics: A comparison study of patients with achalasia before and after endoscopic dilation and non-achalasia controls. Neurogastroenterol Motil 33(12): e14133, Dec 2021 Notes: doi: 10.1111/nmo.14133. Epub 2021 Apr 19.

McGowan EC, Keller JP, Muir AB, Dellon ES, Peng R, Keet CA, Jensen ET.: Distance to pediatric gastroenterology providers is associated with decreased diagnosis of eosinophilic esophagitis in rural populations. J Allergy Clin Immunol Pract 9(12): 4489-4492.e2, Dec 2021 Notes: doi: 10.1016/j.jaip.2021.08.034. Epub 2021 Sep 14.

2020

Muir AB, Whelan KA, Dougherty MK, Aaron B, Navarre B, Aceves SS, Dellon ES,Jensen ET: The potential for malignancy from atopic disorders and allergic inflammation: A systematic review and meta-analysis. Clin Exp Allergy 50(2): 147-159, Feb 2020 Notes: doi: 10.1111/cea.13537. Epub 2019 Dec 20.

Spergel JM, Elci OU, Muir AB, Liacouras CA, Wilkins BJ, Burke D, Lewis MO,Brown-Whitehorn T, Cianferoni A: Efficacy of Epicutaneous Immunotherapy in Children with Milk-Induced Eosinophilic Esophagitis. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association 18(2): 328-336.e7, Feb 2020 Notes: doi: 10.1016/j.cgh.2019.05.014. Epub 2019 May 14.

Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB: Modeling Epithelial Homeostasis and ReactiveEpithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Curr Protoc Stem Cell Biol 52(1): e106, Mar 2020 Notes: doi: 10.1002/cpsc.106.

Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB*, Nakagawa H.* (*denotes co-senior authorship): Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clin Gastroenterol Hepatol 18(7): 1475-1482.e1, Jun 2020 Notes: doi: 10.1016/j.cgh.2019.08.055. Epub 2019 Sep 6.

Pesek RD, Reed CC, Collins MH, Muir AB, Fulkerson PC, Menard-Katcher C, FalkGW, Kuhl J, Magier AZ, Ahmed FN, Demarshall M, Gupta A, Gross J, Ashorobi T,Carpenter CL, Krischer JP, Gonsalves N, Hirano I, Spergel JM, Gupta SK, FurutaGT, Rothenberg ME, Dellon ES: Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. Dig Dis Sci 65(7): 2024-2035, Jul 2020 Notes: doi: 10.1007/s10620-019-05961-4. Epub 2019 Nov 26.

2019

Muir Amanda B, Jensen Elizabeth T, Wechsler Joshua B, Menard-Katcher Paul, Falk Gary W, Aceves Seema S, Furuta Glenn T, Dellon Evan S, Rothenberg Mark E, Spergel Jonathan M: Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. The journal of allergy and clinical immunology. In practice Mar 2019.

Spergel Jonathan M, Elci Okan U, Muir Amanda B, Liacouras Chris A, Wilkins Benjamin J, Burke Deirdre, Lewis Megan O, Brown-Whitehorn Terri, Cianferoni Antonella: Efficacy of Epicutaneous Immunotherapy in Children with Milk-Induced Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association May 2019.

Pesek Robert D, Reed Craig C, Muir Amanda B, Fulkerson Patricia C, Menard-Katcher Calies, Falk Gary W, Kuhl Jonathan, Martin Ellen K, Magier Adam Z, Ahmed Faria, Demarshall Maureen, Gupta Ankur, Gross Jonathan, Ashorobi Tokunbo, Carpenter Christina L, Krischer Jeffrey P, Gonsalves Nirmala, Spergel Jonathan M, Gupta Sandeep K, Furuta Glenn T, Rothenberg Marc E, Dellon Evan S: Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. The American journal of gastroenterology 114(6): 984-994, Jun 2019.

Kasagi Yuta, Dods Kara, Wang Joshua X, Chandramouleeswaran Prasanna M, Benitez Alain J, Gambanga Fiona, Kluger Jonathan, Ashorobi Tokunbo, Gross Jonathan, Tobias John W, Klein-Szanto Andres J, Spergel Jonathan M, Cianferoni Antonella, Falk Gary W, Whelan Kelly A, Nakagawa Hiroshi, Muir Amanda B: Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α. The Journal of allergy and clinical immunology 144(1): 171-182, Jul 2019.

Kennedy Katie, Muir Amanda B, Grossman Andrew, Brown-Whitehorn Terri, Cianferoni Antonella, Spergel Jonathan M, Furuta Glenn T, Wilkins Benjamin J, Shuker Michele, Ruffner Melanie A: Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. The journal of allergy and clinical immunology. In practice 7(6): 2059-2061, Jul - Aug 2019.

Ruffner Melanie A, Song Li, Maurer Kelly, Shi Lihua, Carroll Margaret C, Wang Joshua X, Muir Amanda B, Spergel Jonathan M, Sullivan Kathleen E: Toll-like receptor 2 stimulation augments esophageal barrier integrity. Allergy Jul 2019.

Kijima Takashi, Nakagawa Hiroshi, Shimonosono Masataka, Chandramouleeswaran Prasanna M, Hara Takeo, Sahu Varun, Kasagi Yuta, Kikuchi Osamu, Tanaka Koji, Giroux Veronique, Muir Amanda B, Whelan Kelly A, Ohashi Shinya, Naganuma Seiji, Klein-Szanto Andres J, Shinden Yoshiaki, Sasaki Ken, Omoto Itaru, Kita Yoshiaki, Muto Manabu, Bass Adam J, Diehl J Alan, Ginsberg Gregory G, Doki Yuichiro, Mori Masaki, Uchikado Yasuto, Arigami Takaaki, Avadhani Narayan G, Basu Devraj, Rustgi Anil K, Natsugoe Shoji: Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells. Cellular and molecular gastroenterology and hepatology 7(1): 73-91, 2019.

Shaverdashvili Khvaramze, Padlo Jennie, Weinblatt Daniel, Jia Yang, Jiang Wenpeng, Rao Divya, Laczkó Dorottya, Whelan Kelly A, Lynch John P, Muir Amanda B, Katz Jonathan P: KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF. PloS one 14(4): e0215746, 2019.

2018

Whelan KA, Muir AB, Nakagawa H: Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine. Cellular and molecular gastroenterology and hepatology 5(4): 461-478, Jan 2018.

Cianferoni A, Ruffner MA, Guzek R, Guan S, Brown-Whitehorn T, Muir A, Spergel JM: Elevated expression of activated T2 cells and milk-specific T2 cells in milk-induced eosinophilic esophagitis. Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology 120(2): 177-183.e2, Feb 2018.

Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang M-L, Liacouras CA, Muir AB, Sleiman PMa, Hakonarson H, Spergel JM, Cianferoni A: Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clinical and translational gastroenterology 9(3): 139, Mar 2018.

Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton E, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H: The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes. Cellular and molecular gastroenterology and hepatology 5(3): 333-352, Mar 2018 Notes: *co-senior author.

Muir AB: Eosinophilic Esophagitis. Current problems in pediatric and adolescent health care 48(3): 99-101, Mar 2018.

Ruffler MA, Brown-Whitehorn TF, Cianferoni A, Gober L, Shuker M, CSP, Muir AB, Liacouras CA, Spergel JM: Clinical tolerance in eosinophilic esophagitis. JACI: In Practice 6(2): 661-663, Mar-Apr 2018.

Godwin B, Liacouras C, Mehta, Eisenberg J, Agawu A, Brown-Whitehorn , Ruffner MA, Verma R, Cianferoni A, Spergel JM, Muir AB: A Review of Tertiary Referrals for Management of Pediatric Esophageal Eosinophilia. Frontiers in pediatrics 6: 173, Jun 2018.

Muir AB, Wang JX, Nakagawa H.: Epithelial-stromal crosstalk and fibrosis in eosinophilic esophagitis. J Gastroenterol. 2019 Jan;54(1):10-18. doi: 10.1007/s00535-018-1498-3. Epub 2018 Aug 12.

2017

Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang M-L, Furuta GT, Falk GW, Spergel JM, Nakagawa H: Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut 66(7): 1197-1207, Jul 2017.

Menard-Katcher C, Benitez AJ, Pan Z, Ahmed FN, Wilkins BJ, Capocelli KE, Liacouras CA, Verma R, Spergel JM, Furuta GT, Muir AB: Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort. The American journal of gastroenterology 112(9): 1466-1473, Sep 2017 Notes: See editorial on this paper by Carlson:Widening the Use of the Functional Lumen Imaging Probe to Kids With Eosinophilic Esophagitis: Esophageal Narrowing is not Just an Adult Problem.

2016

Dellon ES, Collins MH, Bonis PA, Leung J, Capocelli KE, Dohil R, Falk GW, Furuta GT, Menard-Katcher C, Gupta SK, Hirano I, Hiremath GS, Kagalwalla AF, Wershil BK, Liacouras CA, Muir AB, Mukkada VA, Putnam PE, Schoepfer AM, Straumann A, Wo JM, Yang G-Y, Rothenberg ME, Gonsalves N: Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association 14(12): 1842-1844, Dec 2016.

Chandramouleeswaran Prasanna M, Shen Dawen, Lee Anna J, Benitez Alain, Dods Kara, Gambanga Fiona, Wilkins Benjamin J, Merves Jamie, Noah Yuliana, Toltzis Sarit, Yearley Jennifer H, Spergel Jonathan M, Nakagawa Hiroshi, Malefyt Rene deWaal, Muir Amanda B, Wang Mei-Lun: Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE). PloS one 11(3): e0150968, 2016 Notes: *co-corresponding author.

Muir A1, Otero H, Blinman T, Wen J: Use of Magnetic Resonance Imaging With Hepatobiliary-Specific Contrast Agent for Precise Localization of a Bile Duct Leak. Journal of Pediatric Gastroenterology and Nutrition 63(3): e36, September 2016 Notes: DOI: 10.1097/MPG.0000000000000531 

Muir AB, Benitez AJ, Dods K, Spergel JM, Fillon SA: Microbiome and its impact on gastrointestinal atopy. Allergy 71(9): 1256-63, Sep 2016 Notes: *co-corresponding author.

Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Whelan KA, DeMarshall M, Hammer DA, Falk G, Wells RG, Spergel J, Hakagawa H, Wang ML: Eosinophilic Esophagitis-Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior. Journal of Pediatric Gastroenterology and Nutrition 63(2), August 2016 Notes: DOI: 10.1097/MPG.0000000000001100.

Dellon Evan S, Collins Margaret H, Bonis Peter A, Leung John, Capocelli Kelley E, Dohil Ranjan, Falk Gary W, Furuta Glenn T, Menard-Katcher Calies, Gupta Sandeep K, Hirano Ikuo, Gonsalves Nirmala, Hiremath Girish S, Kagalwalla Amir F, Wershil Barry K, Liacouras Chris A, Muir Amanda B, Mukkada Vincent A, Putnam Philip E, Schoepfer Alain M, Straumann Alex, Wo John M, Yang Guang-Yu, Rothenberg Marc E: Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Apr 2016.

Muir A, Surrey L, Kriegermeier A, Shaikhkalil A, Piccoli DA: Severe Eosinophilic Gastroenteritis in a Crohn's Disease Patient Treated with Infliximab and Adalimumab. Am J Gastroenterol 111(3): 437-8, Mar 2016 Notes: doi: 10.1038/ajg.2015.438.

Muir AB, Merves J, Liacouras CA: Role of Endoscopy in Diagnosis and Management of Pediatric Eosinophilic Esophagitis. Gastrointestinal endoscopy clinics of North America 26(1): 187-200, Jan 2016.

2015

Muir Amanda B, Dods Kara, Henry Steven J, Benitez Alain J, Lee Dale, Whelan Kelly A, DeMarshall Maureen, Hammer Daniel A, Falk Gary, Wells Rebecca G, Spergel Jonathan, Nakagawa Hiroshi, Wang Mei-Lun: Eosinophilic Esophagitis Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior. Journal of pediatric gastroenterology and nutrition Dec 2015.

Benitez Alain J, Hoffmann Christian, Muir Amanda B, Dods Kara K, Spergel Jonathan M, Bushman Frederic D, Wang Mei-Lun: Inflammation-associated microbiota in pediatric eosinophilic esophagitis. Microbiome 3: 23, 2015.

Merves J, Chandramouleeswaran PM, Benitez AJ, Muir AB, Lee AJ, Lim D,  Dods K, Mehta I, Ruchelli E, Nakagawa H, Spergel J, Wang ML: Altered esophageal histamine receptor expression in eosinophilic esophagitis (EoE): Implications on disease pathogenesis. PLOSone  10(2):e0114831, Feb 2015.

Muir, AB, Dods K, Noah Y, Toltzis S; Modayur Chandramouleeswaran P; Lee A; Bedenbaugh A; Falk GW, Wells R; Nakagawa H; Wang ML: Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition. Experimental Cell Research 330(1): 102-110, Jan 2015.

Muir Amanda B, Dods Kara, Noah Yuli, Toltzis Sarit, Chandramouleeswaran Prasanna Modayur, Lee Anna, Benitez Alain, Bedenbaugh Adam, Falk Gary W, Wells Rebecca G, Nakagawa Hiroshi, Wang Mei-Lun: Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition. Experimental cell research 330(1): 102-10, Jan 2015.

Muir AB, Otero H, Blinman T, Wen J: Use of MRI With Hepatobiliary Specific Contrast Agent For Precise Localization of A Bile Duct Leak. Journal of Pediatric Gastroenterology, Hepatology, and Nutrition Jan 2015 Notes: E-Published ahead of print. 

Books

Chapters

2022

Atu Agawu and Amanda Muir: "Disorders of the Esophagus" Netter's Pediatrics, 2nd edition. Rebecca Tenney Soeiro, Erin Pete Devon (eds.). Page: 59, Jun 2022.

2015

Muir A, Markowitz JE, Liacouras CA. Allergic and Eosinophilic Gastrointestinal Disease. In: Pediatric Allergy: Principles and Practice. 3rd ed. Philadelphia: Elsevier, 2015.

2014

Muir A, Franciosi JP, Markowitz JE, Liacouras CA. Eosinophilic Esophagitis, Gastroenteritis, and Colitis. In: Metcalfe DD, Sampson HA, Simon RA, Lack G, editors. Food Allergy. 5th ed. Malden, MA: Wiley-Blackwell Publishers, 2014.

2012

Muir A, Pineiro-Carrero VM. Encopresis. In: Schwartz MW, editor. 5 Minute Pediatric Consult. 6th ed. Philadelphia, PA: Lippincott, Williams & Wilkins, 2012.

Muir A, Liacouras CA. Vomiting. In: Zorc JJ, editor. Clinical Handbook of Pediatrics. Philadelphia, PA: Lippincott, Williams & Wilkins, 2012.

2010

Kamath B, Rand E, Muir A. Nutritional considerations in pediatric liver transplantation. In: Nutrition, Diet Therapy, and the Liver. CRC Press, 2010.

Posters and Presentations

2023

Muir AB, Bailey D, Abonia P, Menard-Katcher C, Howard A, Lynch K, Dorrell R, Mehta P, Chang J, Pesek R, Khoury P, Klion A, Dellon E, Rothenberg ME, Furuta G, Gupta S, Chehade M, Wright, B, Jensen ET: Disparities in follow up after esophageal food impaction. Digestive Disease Week, Poster Presentation May 2023.

Sasaki M, Hara T, Wang J, Karakasheva T, Muir AB: "FOXM1 regulates epithelial homeostasis in Eosinophilic Esophagitis" Digestive Disease Week, Oral Presentation given by Trainee Masaru Sasaki (plenary) May 2023.

Umeweni C, Alston M, Wolnerman Y, Bendavid A, Spergel Z, Lynch K, Thanawala S, Strauss A, Muir A, Kennedy K: "Symptomatic, Endoscopic, and Histologic Progression of Eosinophilic Esophagitis in a Longitudinal Pediatric Cohort." Poster Presentation. Digestive Diseases Week. Chicago, IL May 2023.

Kennedy K, Umeweni C, Alston M, McCormack S, Allen-Taylor L, Benitez A, Goh V, Maqbool A, Albenberg L, Brown-Whitehorn T, Cianferoni A, Muir A.: Structured Feeding Evaluations Correlate with Esophageal Remodeling in Pediatric Eosinophilic Esophagitis. North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting. Poster Presentation. San Diego, California.  October 2023.

Kennedy K, Wang J, Sasaki M, Ishikawa S, Umeweni C, Alston M, McMillan E, Karakasheva T, Muir A.: Lysyl Oxidase Regulates Epithelial Differentiation in Eosinophilic Esophagitis. Oral presentation by trainee. North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting. San Diego, California. *Trainee abstract award October 2023.

2022

Hara T, Sasaki M, Wang J,  Kasagi Y, Karakasheva TA, Muir AB: Adenosine supports epithelial homeostasis and autophagy in eosinophilic esophagitis. Digestive Disease Week, San Diego, CA, Oral Presentation by trainee Takeo Hara May 2022 Notes: *AGA Fellow Abstract of the Year Award.

Sasaki M, Hara T,  Wang J,  Kasagi Y, Karakasheva TA, Muir AB: Lysyl oxidase regulates epithelial cell differentiation and barrier integrityin eosinophilic esophagitis. Digestive Disease Week, San Diego, CA, Oral Presentation by trainee Masaru Sasaki May 2022 Notes: *American Partnership for Eosinophilic Disorders Abstract Award.

2021

Ackerman S, Muir AB, Pan Z, Benitez AJ, Grozdanovic M, Burger C, Spergel J, Furuta G, Rothman J, Dolinksy L, Menard-Katcher C: Clinical Validation of the minimally invasive 1-hour esophageal string test (EST) EoE-Score for discriminating active from inactive mucosal inflammation in pediatric EoE North American Society for Gastroenterology, Hepatology, and Nutrition Annual Conference, Virtual, Oral Presentation December 2021.

Burger C, Menard-Katcher C, Pan Z, Rothman J, Benitez AJ, Grozdanovic M, Wilkins B, Arnold M, Spergel J, Furuta G, Ackerman S, Muir AB: Markers of esophageal inflammation and chronic remodeling captured by the minimally invasive capsule based device provide comprehensive assessment of disease activity in EoE North America Society for of Gastroenterology, Hepatology, and Nutrition Annual Conference, Virtual, Poster Presentation December 2021.

Rothman J, Rand E, Loomes K, Muir AB: Clinical features and management of concomitant post-transplant lympoproliferative disease and eosinophilic gastrointestinal disease in pediatric liver transplant.  North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Conference, Virtual, Poster Presentation by Trainee Joshua Rothman December 2021.

2018

Lectures by Invitation

2024

Muir AB. "Learn from Our Mistakes: Optimize Your Fellowship Years", North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition First Year Fellows Conference, Orlando, FL. Jan 2024.

2023

Muir AB. "Working with patient advocacy groups: How to work for the same goal", North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Annual Conference.  San Diego, CA. Oct 2023.

Muir AB. "Obstacles to Feeding in Eosinophilic Esophagitis", Keynote Address, Pediatric Digestive Health Conference, Atlanta, GA. Aug 2023.

Muir AB. "Fibrosis in EoE: Is it reversible?_Lessons learned from IBD", Digestive Disease Week Annual Meeting, Chicago, IL. May 2023.

Muir AB. "Eosinophilic esophagitis: _Translational approaches to diagnostic and therapeutic challenges", Comer Children's Hospital, Chicago, IL. Feb 2023.

Muir AB. "What primary care and ED physicians need to know about EoE"? American College of Gastroenterology Virtual Grand Rounds. Jan 2023.

2022

Muir AB. "Translational Research Approaches to Eosinophilic Esophagitis" Western New York Joint Allergy-GI Annual Conference, Skaneateles, NY; *Keynote Address. Nov 2022.

Muir AB. "Meet the Professor: Sustaining a Career In Research", NASPGHAN Annual Meeting, Orlando, FL. Oct 2022.

Muir AB. "Epithelial-Fibroblast interactions drive fibrosis in Eosinophilic Esophagitis", FASEB, Steamboat, CO. Aug 2022.

Muir AB. "Gastro Bites" AGA sponsored updates in Eosinophilic Esophagitis (virtual). May 2022.

Muir AB. "AGA Eosinophilic Esophagitis Guideline Education" (Virtual). Apr 2022.

Muir AB. "Pro-Con: Monitoring EoE by Symptoms or Endoscopy", American Academy of Allergy, Asthma, and Immunology Annual Conference, Phoenix, AZ. Feb 2022.

Muir AB. "Eosinophilic Esophagitis: Management, Treatment and Future Directions", Connecticut Children's Hospital Grand Rounds, Hartford, CT (virtual). Jan 2022.

2021

Muir AB. American College of Gastroenterology: Grand Rounds for EoE, (Virtual). Jul 2021.

Muir AB. "Updates in EoE Research", American Partnership for Eosinophilic Disorders Conference, Virtual. Jul 2021.