Ana Recober, MD

Ana Recober, MD

Ana Recober, MD, is a neurologist at Children’s Hospital of Philadelphia specializing in the care of adolescents and young adults.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)


Ana Recober, MD, is an attending physician and scientist with an interest in Headache Medicine. She is board certified in headache medicine, neurology and psychiatry. Her clinic practice is dedicated to headache diagnosis and management, with a focus in adolescents and young adults. 

Dr. Recober also runs an active research program that includes both clinical and basic research. Her laboratory is dedicated to elucidate the molecular basis of migraine and other headache disorders, with the final goal of finding better treatments for headache patients.

Dr. Recober earned her medical degree at the University of Malaga Medical School, Malaga, Spain. She completed her residency in neurology, and a fellowship in headache medicine at the University of Iowa, Iowa City, IA.

Education and Training

Medical School

MD - University of Málaga Medical School, Málaga, Spain


Neurology - University of Iowa, Iowa City, IA


Headache and Pain - University of Iowa, Iowa City, IA

Board Certification

Psychiatry and Neurology

Titles and Academic Titles

Attending Physician

Assistant Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Neurobiology of migraine and other trigeminal mediated pain disorders

Molecular basis of trigeminal pain disorders

Mechanisms of migraine progression from episodic to chronic




Dindo LN, Recober A, Haddad R, Calarge CA. Comorbidity of Migraine, Major Depressive Disorder, and Generalized Anxiety Disorder in Adolescents and Young Adults. Int J Behav Med. 2017 Aug;24(4):528-534. doi: 10.1007/s12529-016-9620-5.

Kaiser EA, Rea BJ, Kuburas A, Kovacevich BR, Garcia-Martinez LF, Recober A, Russo AF. Anti-CGRP antibodies block CGRP-induced diarrhea in mice. Neuropeptides. 2017 Aug;64:95-99. doi: 10.1016/j.npep.2016.11.004. Epub 2016 Nov 14.


Rossi HL, Lara O, Recober A. Female sex and obesity increase photophobic behavior in mice. Neuroscience. 2016 Sep 7;331:99-108. doi: 10.1016/j.neuroscience.2016.06.022. Epub 2016 Jun 17.

Kalil GZ, Recober A, Hoang-Tienor A, Bridget Zimmerman M, Haynes WG, Pierce GL. Higher augmentation index is associated with tension-type headache and migraine in middle-aged/older humans with obesity. Obesity (Silver Spring). 2016 Apr;24(4):865-70. doi: 10.1002/oby.21414. Epub 2016 Feb 5.

Rossi HL, Broadhurst KA, Luu AS, Lara O, Kothari SD, Mohapatra DP, Recober A. Abnormal trigeminal sensory processing in obese mice. Pain. 2016 Jan;157(1):235-46. doi: 10.1097/j.pain.0000000000000355. 


Rossi HL, Recober A. Photophobia in primary headaches. Headache. 2015;55(4):600-604.


Dindo L, Recober A, Marchman J, O’Hara M, Turvey C. Impact of a One-Day Behavioral Intervention on Headaches: A Pilot Study in Depressed Migraine Patients. (revision submitted to Headache).

Rossi HL, Luu KS, DeVilbiss JL, Recober A. Obesity lowers the threshold of trigeminal activation: Implications for migraine. Eur J Pain. 2013 May;17(5):649-653. [Epub Oct 2012] (PMID: 23070979)

Rossi HL, Luu KS, Kothari SD, Kuburas A, Neubert JK, Caudle RM, Recober A. Effects of diet-induced obesity on motivation and pain behavior in an operant assay. Neuroscience. 2013 Apr;235:87-95. (PMID: 23333672)


Kaiser E, Kuburas A, Recober A, Russo AF. Modulation of CGRP-induced light aversion in wildtype mice by a 5HT1B/D agonist. J Neurosci. 2012 Oct;32(44):15439-15449. (PMID: 23115181)

Dindo L, Recober A, Marchman J, Turvey C, O’Hara M. One day behavioral treatment for patients with comorbid depression and migraine: A pilot study. Behaviour Research and Therapy. 2012 May;50(9):537-543. (PMID: 22728646)



Recober A, Kruger J, Hoang-Tienor A, Burns T. Cardiovascular Profile and the Risk of Migraine in Adulthood”. International Headache Congress Platform presentation # OR25, Boston, MA (2013).

Recober A, Luu AS, Rossi H, Kothari S, Lara O. Trigeminal Pain is Increased by High-Fat Diet Induced Obesity in Mice. International Headache Congress Abstract #P309, Boston, MA (2013).

Recober A, Luu AS, Rossi H, Kothari S, Lara O. Photophobia in Obese Mice: Implications for Migraine. International Headache Congress Abstract #P318, Boston, MA (2013).




Russo AF, Recober A, Zhang Z, Marquez de Prado B, Kaiser E, Kuburas A. Biological relevance of CGRP in the context of migraine. In Frontiers in Headache Research, vol. 18, Role of calcitonin generelated peptide (CGRP) and adrenomedullin (AM) in migraine; ed: Jes Olesen. Oxford University Press.

Awards and Honors

2013, Best Doctors in America

2012, The University of Iowa 2012 Inventor Award

2010, Harold Wolff-John Graham Award: An Award for Headache/Facial Pain Research American Academy of Neurology, Toronto, Canada

2009-2014, K08 – Mentored Clinical Scientist Research Career Development Award NIH/NINDS

2007-2009, Training Grant in Pain Research, University of Iowa

2007, Young Investigator Award, 6th International Symposium on the CGRP Family

2004, Richard W. Fincham Award, University of Iowa

2002, Resident Travel Award, American Headache Society

1996, Medical Student Research Scholarship, University of Málaga Medical School

1996, Summer Visiting Student Scholarship, Cleveland Clinic Foundation

1995-1997, Alumna Interna, University of Malaga Medical School

1994, Summer Visiting Student Scholarship, International Federation of Medical Student Associations

1991-1996, Elected Council Member, University of Málaga Medical School

Editorial and Academic Positions

Editorial positions

2012-present, F1000 Research, Editorial Board member

2010-present, Co-Editor, Headache News of the American Headache Society

2010-present, Online Editorial Board Member, Headache 

Ad Hoc reviewer

2013-present, Psychoneuroendocrinology

2013-present, The International Journal of Neuroscience

2012-present, PLoS ONE

2011-present, Behavioural Brain Research

2010-present, Pharmaceuticals

2008-present, Headache

2008-present, Faculty member of Faculty of 1000 Medicine (reviewer)

2008-present, Cephalalgia

Leadership and Memberships

Memberships in professional organizations

American Academy of Neurology

American Headache Society

Headache Cooperative of the Pacific

International Headache Society

National Headache Foundation

Society for Neuroscience