Amrita Sarkar, PhD
Locations: University of Pennsylvania Abramson Cancer Center (ACC)
About Amrita Sarkar, PhD
Titles
Senior Principal Scientist
Research Assistant Professor of Pediatrics (Hematology), University of Pennsylvania School of Medicine
Awards and Honors
2025, Early Career Travel Award, International Society of Thrombosis and Hemostasis
2025, Abstract Award, Hemostasis & Thrombosis Research Society Scientific Session
2024, Early Career Travel Award, International Society of Thrombosis and Hemostasis
2023, Best Abstract Award, American Association of Immunologists Conference
2021, Early Career Abstract Award, International Society of Thrombosis and Hemostasis
2021, Abstract Achievement Award, 63rd American Society of Hematology Conference
2018, Postdoctoral Trainee Abstract Award and Travel Award, American Association of Immunology Conference
2018, Best Abstract Award with Travel Award, 61st American Association of Hematology
2012, Best Poster Award, National Seminar in "Emerging Trends in Cell and Molecular, Biology", Jadavpur University
2012, Foreign Endowment Fellowship from University of Calcutta
2012-2013, Senior Research Fellowship, University of Calcutta
2011, Best Oral Presentation Award, 32nd Annual Conference of Indian Association of Biomedical Scientists
2010-2012, Junior Research Fellowship, University of Calcutta
Leadership and Memberships
2020-present, International Society on Thrombosis and Haemostasis
Editorial and Academic Positions
Editorial Positions
2026, Guest Editor at Cell, MDPI (Special Issue: Immune-Mediated Thrombosis: From Molecular Mechanisms to Targeted Therapies)
2025-2026, Guest Editor at Disease, MDPI (Special Issue: Immune-Mediated Thrombosis: Mechanisms, Vaccine Association, and Therapeutic Innovations)
2023-present, Reviewer, Biomedicines
2022-present, Reviewer, Vaccine
2022-present, Reviewer, Vetsci
2022-present, Reviewer, Virus
2021-present, Reviewer, Microorganisms
2021-present, Reviewer, Pharmacy
2021-present, Reviewer, Immuno
202-present, Reviewer, Vaccines journal
2020-present, Reviewer, Biomolecules Journal
2020-present, Reviewer, IJERPH Journal
2019-present, Reviewer, Medicina Journal
2019-present, Reviewer, JCM Journal
2019-present, Reviewer, Antibiotics Journal
2019-present, Reviewer, Medsci Journal
2019-present, Reviewer, IJMS Journal
2018-present, Reviewer, Nutrients Journal
Academic and Institutional Committees
2025-2027, ISTH Ethics Committee
2025-present, Organizing Committee from UPENN/CHOP at Annual Philadelphia Workshop on Hemostasis and Thrombosis
Education & training
Undergraduate Degree
BSc in Physiology - University of Calcutta, Kolkata, India
Graduate Degree
MSc in Human Physiology and Pharmacology - University of Calcutta, Kolkata, India
PhD in Physiology and Pharmacology - Department of Physiology, University of Calcutta, Kolkata, India
Fellowship
Post-Doctoral Research Fellow, Department of Biosciences and Bioengineering - IIT Powai, Mumbai, India
Post-Doctoral Research Fellow - Thomas Jefferson University, Philadelphia, PA
Post-Doctoral Research Fellow, Division of Hematology - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2026
Yanki Yarman 1, Xuefei Zhao 1, Hyunsook Ahn 2, Hannah Thomson 1, Amrita Sarkar 2, Tian Yuan 1, Meghan Roberts 1, Jeremy G T Wurtzel 1, Scott L Diamond 3, John J G Tesmer 4 5, Deborah L French 6 7, Maurizio Tomaiuolo 8, Ernest Turro 9, William J Astle 10, Lawrence E Goldfinger 1, Steven E McKenzie 1, Jeffrey L Benovic 11, Timothy J Stalker 1, Mortimer Poncz 2 12, Peisong Ma 1: Understanding how a highly prevalent GRK5 polymorphism affects platelets and enhances https://pubmed.ncbi.nlm.nih.gov/41557909/ 2026.
Liang Zhao 1, Sokratis A Apostolidis 1, Aae Suzuki 1, Amrita Sarkar 2, Qian Guo 3, Felix Li 1, Alex Sagar 4, John Fallon 4, Mohamed A Elzawahry 4, Syed Hussain Abbas 4, Leanne Lanieri 5, Kristen Getchell 5, Susan C Low 5, Kim M Olthoff 6, Emma E Furth 7, Brendan J Keating 3, Peter Friend 4, Mortimer Poncz 2, Abraham Shaked 6, Charles S Abrams 1: Graft-derived VWF drives platelet activation and thrombocytopenia during porcine liver xenotransplantation to brain-dead human recipients. https://pubmed.ncbi.nlm.nih.gov/41805640/ 2026.
2025
Lubica Rauova 1 2, Khalil Bdeir 3, Ann H Rux 3, Manu Thomas Kalathottukaren 4, Jenna Oberg 1, Chanel C La 4 5, David T E Lim 4 5, Vincent Hayes 1, Gavin T Koma 1, Amrita Sarkar 1, Mortimer Poncz 1 2, Jayachandran N Kizhakkedathu 4 5 6, Douglas B Cines 3 7: Destabilization of PF4-antigenic complexes in heparin-induced thrombocytopenia. https://pubmed.ncbi.nlm.nih.gov/40132149/ 2025.
2023
Ngo AT, Skidmore A, Oberg J, Yarovoi I, Sarkar A, Levine N, Bochenek V, Zhao G, Rauova L, Kowalska MA, Eckart K, Mangalmurti NS, Rux A, Cines DB, Poncz M, Gollomp K.: Platelet factor 4 limits neutrophil extracellular trap- and cell-free DNA-induced thrombogenicity and endothelial injury. JCI Insight 8(7): e171054, Nov 2023.
Sarkar A, Khandelwal S, Koma GT, Kim H, Gruel Y, Rollin J, Passam F, Wool GD, Arepally GM, Cines DB, Rauova L, Poncz M.: Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic? Blood Adv 7(6): 4112-4123, Aug 2023.
2022
Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Oldridge DA, Giles JR, Wu JE, Chen Z, Huang YJ, Belman J, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit; Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ.: Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19. Front Immunol 13(1): 834988, Mar 2022.
2021
Khandelwal S, Barnes A, Rauova L, Sarkar A, Rux AH, Yarovoi SV, Zaitsev SS, Lambris JD, Myoung SS, Johnson A, Lee GM, Duarte M, Poncz M, Arepally GM, Cines DB.: Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes. Blood 138(4): 2106-2116, Nov 2021.
2020
Cines DB, Zaitsev S, Rauova L, Rux AH, Stepanova V, Krishnaswamy S, Sarkar A, Kowalska MA, Zhao G, Mast AE, Blumberg LJ, McCrae KR, Poncz M, Hubbard JJ, Pyzik M, Blumberg RS.: FcRn augments induction of tissue factor activity by IgG-containing immune complexes. Blood 135(1): 2085-2093, Jun 2020.
Johnston I, Sarkar A, Hayes V, Koma GT, Arepally GM, Chen J, Chung DW, López JA, Cines DB, Rauova L, Poncz M.: Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation. Blood 135(6): 1270-1280, Apr 2020.
Gollomp K, Sarkar A, Harikumar S, Seeholzer SH, Arepally GM, Hudock K, Rauova L, Kowalska MA, Poncz M.: Fc-modified HIT-like monoclonal antibody as a novel treatment for sepsis. Blood 135(3): 743-754, Mar 2020.
2019
Kolpakov MA, Sikder K, Sarkar A, Chaki S, Shukla SK, Guo X, Qi Z, Barbery C, Sabri A, Rafiq K.: Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy. Cell Physiol Biochem 53(6): 982-998, Jul 2019.
Sarkar A, Carvalho E, D'souza AA, Banerjee R.: Liposome-encapsulated fish oil protein-tagged gold nanoparticles for intra-articular therapy in osteoarthritis. Nanomedicine (Lond) 14(7): 871-887, Apr 2019.
2018
Shukla SK, Sikder K, Sarkar A, Addya S, Rafiq K.: Molecular network, pathway, and functional analysis of time-dependent gene changes related to cathepsin G exposure in neonatal rat cardiomyocytes. Gene 671(1): 58-66, Sep 2018.
2017
Shukla SK, Liu W, Sikder K, Addya S, Sarkar A, Wei Y, Rafiq K.: HMGCS2 is a key ketogenic enzyme potentially involved in type 1 diabetes with high cardiovascular risk. Sci Rep 7(1): 4590, Jul 2017.
2015
Dyondi D, Sarkar A, Banerjee R.: Joint Surface-Active Phospholipid-Mimetic Liposomes for Intra-Articular Delivery of Paclitaxel. J Biomed Nanotechnol 11(7): 1225-35, Jul 2015.
2014
Sarkar A, Datta P, Das AK, Gomes A.: Anti-rheumatoid and anti-oxidant activity of homeopathic Guaiacum officinale in an animal model. Homeopathy 103(2): 133-8, Apr 2014.
Editorials, Reviews, Chapters
2026
Ana I Casanegra 1, Sobia Sharif 2, Cynthia Rothschild 3, Nicoletta Riva 4, Amrita Sarkar 5, Fernanda A Orsi 6, Robert A S Ariëns 7: International Society on Thrombosis and Haemostasis conflict of interest management and tools: presentation of a case study. https://pubmed.ncbi.nlm.nih.gov/41921860/ 2026.