Background

Pediatric urologist Gregory Tasian, MD, MSc, MSCE, is dedicated to a practice of compassionate care for children and adolescents. He strives to make sure families know all the available treatment options for their child. And he supports shared decision-making with families when considering alternative treatments.

Dr. Tasian knew he wanted to be a surgeon from the time he was 7 years old. He loved using his mind and hands to “fix” things as a child. It wasn’t until medical school that he discovered that he wanted to become a urologist.

“Urology offers the opportunity to improve the quality of patient’s lives. Whether it be removing a kidney stone that is blocking the flow of urine from the kidney or creating a new bladder to restore function due to congenital abnormalities or cancer. I wanted an area of medicine where I could apply discoveries in research to improve patients’ lives. There are so many opportunities to do this in Urology,” he explains.

In the Division of Urology, Dr. Tasian focuses his clinical efforts on the surgical and medical management of children with kidney stones. He became interested in pediatric kidney stone disease during his residency. As he explains, the condition was once uncommon.

“When I was in medical school in the early 2000s, very few children developed kidney stones. In the last 20 years, the number of youth who develop kidney stones has increased for reasons that are still unclear. My interest, what I am most passionate about, is to understand what is causing this modern epidemic. This understanding will provide insight into how to reduce kidney stone recurrence across a lifespan.”

Advancements in technology are improving surgery for kidney stones. For example, the instruments used for this surgery are becoming smaller. Urology is (and always will be) at the cusp of technological innovation,” Dr. Tasian explains. “This means that we have the opportunity to use new devices and procedures to make surgery more effective, safer and less painful in the future.”

Dr. Tasian’s research group uses a large data analysis, behavioral economics, dietary assessment, and evaluation of urine and stool to discover determinants of kidney stone disease with the goal of translating this knowledge into new treatments for kidney stone prevention. He directs a large microbiome research program that recently published the first evidence that oral antibiotics increase the risk of kidney stones.

His group also analyzes ultrasound of the kidney to discover novel biomarkers of chronic kidney disease progression for children with congenital urologic disease. He collaborates with imaging experts at the University of Pennsylvania to use machine learning to develop automated methods to predict the risk of chronic kidney disease early in life when kidney function is still preserved.

The long-term goal of Dr. Tasian’s research program is to improve the lives of children with nephrolithiasis and congenital urologic disease.

Education and Training

Medical School

MD - Baylor College of Medicine, Houston, TX

Internship

Surgery - University of California, San Francisco, San Francisco, CA

Residency

Urology - University of California, San Francisco, San Francisco, CA

Fellowship

Pediatric Urology - Children's Hospital of Philadelphia, Philadelphia, PA

Graduate Degree

MSc in Neuroscience - Oxford University, Oxford, England

Master of Science in Clinical Epidemiology (MSCE) - University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Attending Urologist

Associate Professor of Urology in Surgery, Perelman School of Medicine at the University of Pennsylvania

Associate Professor of Epidemiology in Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Research Interests

Dr. Tasian's research focuses on two areas: epidemiology and clinical trials in nephrolithiasis (kidney stone disease) among children and adults, and applying machine learning to improve understanding of the pathophysiology, prediction of outcomes and identification of therapeutics in children and adults with benign urologic disease.

As PI of the CHOP/Penn Clinical Center for the NIDDK-supported Urinary Stone Disease Research Network (USDRN), Dr. Tasian co-leads the Prevention of Urinary Stones with Hydration (PUSH) randomized controlled trial, which is examining the effect of behavioral economic approaches to maintain high fluid intake to decrease stone recurrence, and is the first and largest clinical trial in kidney stone disease to include adolescents and adults. Dr. Tasian is also the Director of the Pediatric KIDney Stone (PKIDS) Care Improvement Network. PKIDS is a community of investigators, patients, caregivers, clinicians, industry partners, and payers who generate and apply knowledge that improves outcomes for children with kidney stones at 26 health systems in North America. Dr. Tasian also directs a large microbiome research program that published the first evidence that antibiotics increase risk of kidney stones, particularly for children. His group also discovered that dysbiosis of the gut microbiome is associated with early-onset calcium kidney stones. These studies identified a network of bacteria involved in butyrate production and oxalate degradation that is less abundant in kidney stone formers.

In addition, Dr. Tasian also leads a large NIH-funded program that applies machine learning to complex data to improve the diagnosis, risk stratification, and prediction of treatment responses of children and adults with benign urological disease. He is the Director of the NIDDK P20 CHOP/Penn Center for Machine Learning in Urology, which is automating the measurement of kidney stones and predicting the probability of spontaneous stone passage for children and adults with ureteral stones. His group partners with Yong Fan at Penn to apply deep learning to extract informative features from renal ultrasound and urodynamics tracings to identify children at increased risk of chronic kidney disease progression early in life when glomerular filtration is still preserved. These features, which can be measured in real-time, will identify children who are most likely to benefit from early interventions to preserve kidney function.

Publications

Papers

2020

Bernard J, Song L, Henderson B, Tasian GE: Association between daily water intake and 24-hour urine volume among adolescents with kidney stones. Urology Jan. 28 2020 (Epub) Notes: doi: 10.1016/j.urology.2020.01.024.

Denburg MR, Koepsell KG, Lee JJ, Gerber J, Bittinger K, Tasian GE: Perturbations of the gut microbiome and metabolome in children with calcium oxalate kidney stone disease. Journal of the American Society of Nephrology May 7 2020 (Epub) Notes: doi: 10.1681/ASN.2019101131.

Ellison JS, Tasian GE: The impact of sex and gender on clinical care and research design in nephrolithiasis. Urology May 5 2020 (Epub) Notes: doi: 10.1016/j.urology.2020.04.089.

Yin S, Peng Q, Li H, Zhang Z, You X, Fischer K, Furth SL, Fan Y, Tasian G: Multi-instance deep learning of ultrasound imaging data for pattern classification of congenital abnormalities of the kidney and urinary tract in children. Urology 2020 (in press).

Lawman HG, Grossman S, Lofton X, Tasian G, Patel AI: Hydrate Philly: An intervention to increase water access and appeal in recreation centers. Preventing Chronic Diseases 17: E15, Feb. 20 2020.

Vicedo-Cabrera AM, Goldfarb DS, Kopp RE, Song L, Tasian GE: Sex differences in the temperature dependence of kidney stone presentations: A population-based aggregated case-crossover study. Urolithiasis 48(1): 37-46, Feb. 2020 Notes: Epub Mar. 21, 2019.

Yin S, Peng Q, Li H, Zhang Z, You X, Fischer K, Furth SL, Tasian GE, Fan Y: Automatic kidney segmentation in ultrasound images using subsequent boundary distance regression and pixelwise classification networks. Medical Image Analysis 60: 101602, Feb. 2020 Notes: Epub Nov. 8, 2019.

Bowen DK, Song L, Faerber J, Kim J, Scales CD, Tasian GE: Retreatment after ureteroscopy and shockwave lithotripsy: A population-based comparative effectiveness study. Journal of Urology 203(6): 1156-1162, June 2020 Notes: Epub Mar. 24, 2020.

Shah AA, Carey RM, Brant JA, Tasian GE, Ziemba JB. An Analysis of the US News & World Report Methodology for Attribution of Specialty Care in Otolaryngology and Urology [published online ahead of print, 2020 Jul 21]. Otolaryngol Head Neck Surg. 2020;194599820941016. doi:10.1177/0194599820941016

Rubin D, Huang J, Fisher BT, Gasparrini A, Tam V, Song L, Wang X, Kaufman J, Fitzpatrick K, Jain A, Griffis H, Crammer K, Morris J, Tasian GE. Association of Social Distancing, Population Density, and Temperature With the Instantaneous Reproduction Number of SARS-CoV-2 in Counties Across the United States. JAMA Netw Open. 2020;3(7):e2016099. Published 2020 Jul 1. doi:10.1001/jamanetworkopen.2020.16099

2019

Yin S, Peng Q, Li H, Zhang Z, You X, Liu H, Fischer K, Furth SL, Tasian GE, Fan Y: Multi-instance deep learning with graph convolutional neural networks for diagnosis of kidney diseases using ultrasound imaging. Uncertainty for Safe Utilization of Machine Learning in Medical Imaging & Clinical Image-based Procedures 11840: 146-154, Oct. 2019 Notes: Epub Oct. 7, 2019.

Zheng Q, Furth SL, Tasian GE, Fan Y: Computer-aided diagnosis of congenital abnormalities of the kidney and urinary tract in children based on ultrasound imaging data by integrating texture image features and deep transfer learning image features. Journal of Pediatric Urology 15(1): 75.e1-75.e7, Feb. 2019.

Chu DI, Abraham AG, Tasian GE, Denburg MR, Ross ME, Zderic SA, Furth SL: Urologic care and progression to end-stage kidney disease: a Chronic Kidney Disease in Children (CKiD) nested case-control study. Journal of Pediatric Urology 15(3): 266.e1-266.e7, Mar. 2019.

Tasian GE, Ross M, Song L, Audrain-McGovern J, Wiebe D, Warner SG, Henderson B, Patel A, Furth SL: Ecological momentary assessment of factors associated with water intake among adolescents with kidney stone disease. The Journal of Urology 201(3): 606-614, Mar. 2019.

Lawman HG, Lofton X, Grossman S, Root M, Perez M, Tasian G, Patel A: A randomized trial of a multi-level intervention to increase water access and appeal in community recreation centers. Contemporary Clinical Trials 79: 14-20, Apr. 2019.

Yin S, Zhang Z, Li H, Peng Q, You X, Furth SL, Tasian GE, Fan Y: Fully-automatic segmentation of kidneys in clinical ultrasound images using a boundary distance regression network. Proceedings. IEEE International Symposium on Biomedical Imaging 2019: 1741-1744, Apr 2019.

Lee AS, McGarry L, Bowen DK, Tasian GE: Patient characteristics associated with completion of 24-hour urine analyses among children and adolescents with nephrolithiasis. Urology 127: 102-106, May 2019.

2018

Tasian GE, Jemielita T, Goldfarb DS, Copelovitch L, Gerber JS, Wu Q, Denburg MR: Oral antibiotic exposure and kidney stone disease. Journal of the American Society of Nephrology 29(6): 1731-1740, June 2018 Notes: Epub May 10, 2018.

Kurtzman JT, Song L, Ross ME, Scales CD Jr., Chu DI, Tasian GE: Urology consultation and emergency department revisits for children with urinary stone disease. Journal of Urology 200(1): 180-186, July 2018 Notes: Epub Feb. 21, 2018.

Zheng Q, Warner S, Tasian G, Fan Y: A dynamic graph cuts method with integrated multiple feature maps for segmenting kidneys in 2D ultrasound images. Academic Radiology 25(9): 1136-1145, Sept. 2018 Notes: Epub Feb. 12, 2018.

Chu DI, Tan JM, Mattei P, Simpao AF, Costarino AT, Shukla AR, Rossano JW, Tasian GE: Outcomes of laparoscopic and open surgery in children with and without congenital heart disease. Journal of Pediatric Surgery 53(10): 1980-1988, Oct. 2018.

Ross ME, Vicedo-Cabrera AM, Kopp RE, Song L, Goldfarb DS, Pulido J, Warner S, Furth SL, Tasian GE: Assessment of the combination of temperature and relative humidity on kidney stone presentations. Environmental Research 162: 97-105, Apr. 2018 Notes: (Epub Dec. 28, 2017).

Zheng Q, Tasian G, Fan Y: Transfer learning for diagnosis of congenital abnormalities of the kidney and urinary tract in children based on ultrasound imaging data. Proceedings: IEEE International Symposium on Biomedical Imaging 2018: 1487-1490, Apr. 2018 Notes: Epub May 24, 2018.

Lee AS, Bowen DK, Vatsky S, Zderic SA, Tasian GE: Percutaneous nephrolithotomy in an 8-week-old infant. Canadian Journal of Urology 25(3): 9363-9365, June 2018.

2017

Denburg MR, Leonard MB, Jemielita TO, Golden NH, Tasian G, Copelovitch L: Risk of urolithiasis in anorexia nervosa: A population-based cohort study using the Health Improvement Network. European Eating Disorders Review: the Journal of the Eating Disorders Association 25(5): 406-410, Sept. 2017.

Chu DI, Tan JM, Mattei P, Simpao AF, Costarino AT, Shukla AR, Rossano JW, Tasian GE: Outcomes of laparoscopic and open surgery in children with and without congenital heart disease. Journal of Pediatric Surgery Nov. 2017 Notes: doi: 10.1016/j.jpedsurg.2017.10.052.

Ross ME, Vicedo-Cabrera AM, Kopp RE, Song L, Goldfarb DS, Pulido J, Warner S, Furth SL, Tasian GE. Assessment of the combination of temperature and relative humidity on kidney stone presentations. Environ Res. 2018 Apr;162:97-105. doi: 10.1016/j.envres.2017.12.020. Epub 2017 Dec 28.

Tasian GE, Kabarriti AE, Kalmus A, Furth SL: Kidney stone recurrence among children and adolescents. The Journal of Urology 197(1): 246-252, Jan 2017.

2016

Tasian GE, Ross ME, Song L, Grundmeier RW, Massey J, Denburg MR, Copelovitch L, Warner S, Chi T, Killilea DW, Stoller ML, Furth SL: Dietary zinc and incident calcium kidney stones in adolescence. The Journal of Urology Epub ahead of print, Nov 2016.

Chu DI, Zderic SA, Shukla AR, Srinivasan AK, Tasian GE, Weiss DA, Long CJ, Canning DA, Kolon TF: Does varicocelectomy improve semen analysis outcomes in adolescents without testicular asymmetry? Journal of Pediatric Urology Epub ahead of print, Oct 2016.

Chu DI, Zderic SA, Shukla AR, Srinivasan AK, Tasian GE, Weiss DA, Long CJ, Canning DA, Kolon TF: The natural history of semen parameters in untreated asymptomatic adolescent varicocele patients: a retrospective cohort study. Journal of Pediatric Urology Epub ahead of print, Oct 2016.

Chu DI, Canning DA, Tasian GE. Race and 30-Day Morbidity in Pediatric Urologic Surgery. Pediatrics. 2016 Jun 17. pii: e20154574. [Epub ahead of print].

Tasian GE, Ross ME, Song L, Sas DJ, Keren R, Denburg MR, Chu DI, Copelovitch L, Saigal CS, Furth SL. Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016 Jan 14. pii: CJN.07610715. Epub ahead of print.

2015

Denburg MR, Jemielita TO, Tasian GE, Haynes K, Mucksavage P, Shults J, Copelovitch L. Assessing the risk of incident hypertension and chronic kidney disease after exposure to shockwave lithotripsy and ureteroscopy. Kidney Int. 2015 Oct 28. Epub ahead of print.

Shoag J, Tasian GE, Goldfarb DS, Eisner BH. The new epidemiology of nephrolithiasis. Adv Chronic Kidney Dis. 2015 Jul;22(4):273-8.

Ziemba JB, Canning DA, Lavelle J, Kalmus A, Tasian GE. Patient and institutional characteristics associated with initial computerized tomography in children presenting to the emergency department with kidney stones. J Urol. 2015 May;193(5 Suppl):1848-53. Epub 2014 Oct 8.

2014

Denburg M, Leonard M, Haynes K, Tuchman S, Tasian GE, Shults J, Copelovitch L. Risk of Fracture in Urolithiasis: A Population-Based Cohort Study Using the Health Improvement Network. Clinical Journal of the American Society of Nephrology. Clin J Am Soc Nephrol. 2014 Dec 5;9(12):2133-40. doi: 10.2215/CJN.04340514. Epub 2014 Oct 23.

Tasian GE, Pulido JE, Keren R, Dick AW, Setodji C, Hanley J, Madison R, Saigal CS, Urologic Diseases in America Project. Prevalence and Regional Variation of Initial CT for Pediatric Kidney Stones in the United States. Pediatrics. 134(5): 909-15. Nov. 2014.

Tasian GE, Appa A, Bagga HS, Blaschko S, McCulloch, McAninch JW, Breyer BN. Bicyle-related genitourinary injuries in the United States from 2002-2010. Inj Prev. 2014 Oct;20(5):350-3. doi: 10.1136/injuryprev-2013-041002. Epub 2014 Mar 11.

Ziemba JB, Canning DA, Lavelle J, Kalmus A, Tasian GE. Patient and Institutional Characteristics Associated with Initial CT Use for Children Presenting to the Emergency Department with Kidney Stones. J Urol. 2014 Oct 8. [Epub ahead of print]

Tasian GE, Pulido JE, Gasparrini A, Saigal CS, Horton BP, Landis JR, Madison R, Keren R. Daily mean temperature and clinical kidney stone presentation in five U.S. metropolitan areas: a time-series analysis. Environ Health Perspect. 2014 Oct;122(10):1081-7. doi: 10.1289/ehp.1307703. Epub 2014 Jun 11.

Tasian GE, Cost NG, Granberg CF, Pulido JE, Rivera M, Schwen Z, Schulte M, Fox JA. Tamsulosin and the spontaneous passage of ureteral stones in children: A multi-institutional cohort study. J Urol. 2014 Aug;192(2):506-11. doi: 10.1016/j.juro.2014.01.091. Epub 2014 Feb 8.

Kolon TF, Anthony Herndon CD, Baker LA, Baskin LS, Baxter CG, Cheng EY, Diaz M, Lee PA, Seashore CJ, Tasian GE, Barthold JS. Evaluation and treatment of cryptorchidism: AUA Guideline.  J Urol. 2014 Aug;192(2):337-45. doi: 10.1016/j.juro.2014.05.005. Epub 2014 May 20.

Pulido JE, Furth SL, Zderic SA, Canning DA, Tasian GE. Renal parenchymal area and risk of end stage renal disease in boys with posterior urethral valves. Clin J Am Soc Nephrol. 2014 Mar;9(3):499-505. doi: 10.2215/CJN.08700813. Epub 2013 Dec 5.

2013

Fayad A1, El-Sheikh MG, El-Fayoumy H, El-Sergany R, Abd El Bary A. Effect of extracorporeal shock wave lithotripsy on kidney growth in children. J Urol. 2012 Sep;188(3):928-31. doi: 10.1016/j.juro.2012.04.120. Epub 2012 Jul 20.

Glass AS, Bagga HS, Tasian GE, McGeady JB, McCulloch CE, Blaschko SD, McAninch JW, Breyer BN. No small slam: increasing incidents of genitourinary injury from toilets and toilet seats. BJU Int. 2013 Aug;112(3):398-403. doi: 10.1111/bju.12173. Epub 2013 Jun 14. Cited in PubMed; PMID 23773285.

Christman MS, Kraft KH, Tasian GE, Zderic SA, Kolon TF. Reproducibility and reliability of semen analysis in youths at risk for infertility. J Urol. 2013 Aug;190(2):683-8. doi: 10.1016/j.juro.2013.02.030. Epub 2013 Feb 19. Cited in PubMed; PMID 23434946.

Tasian G, Routh JC. Failure to Reject Does Not Equal Acceptance of Null Hypothesis: Implications for Assessing Safety of ESWL in Children. J Urol. 2013 Apr 11. pii: S0022-5347(13)04058-5. doi: 10.1016/j.juro.2013.02.3233. Epub 2013 Apr 11. Cited in PubMed; PMID 23583860.

Bagga HS, Tasian GE, Fisher PB, McCulloch CE, McAninch JW, Breyer BN. Product related adult genitourinary injuries treated at emergency departments in the United States from 2002 to 2010. J Urol. 2013 Apr;189(4):1362-8. doi: 10.1016/j.juro.2012.10.122. Epub 2012 Nov 2. Cited in PubMed; PMID 23127766.

Bagga HS, Tasian GE, McGeady J., et al. Zip-related genital injury. BJU Int. Epub 2013 Mar 13. doi: 10.1111/bju.12009. Cited in PubMed; PMID 23490164.

Christman MS, Kraft KH, Tasian GE, Zderic SA, Kolon TF. Reproducibility and reliability of semen analyses in youths at risk for infertility.  J Urol. 2013 Epub Feb 19. doi:pii: S0022-5347(13)00299-1. 10.1016/j.juro.2013.02.030. Cited in PubMed; PMID 23434946.

Tasian GE, Wiebe DJ, Casale P. Learning Curve of Robotic Assisted Pyeloplasty for Pediatric Urology Fellows. J Urol. 2013 Feb 11. pii: S0022-5347(13)00276-0. doi: 10.1016/j.juro.2013.02.009. [Epub ahead of print]. Cited in PubMed; PMID 23410982

Tasian GE, Bagga HS, Fisher PB, McCulloch CE, Cinman NM, McAninch JW, Breyer BN. Pediatric genitourinary injuries in the United States from 2002 to 2010. J Urol. 2013 Jan;189(1):288–93. doi: 10.1016/j.juro.2012.09.003. Epub 2012 Nov 19. Cited in PubMed; PMCID: PMC3565612.

2012

Tasian GE, Cooperberg MR, Potter MB, Cowan JE, Greene KL, Carroll PR, et al. PSA screening: determinants of primary-care physician practice patterns. Prostate Cancer Prostatic Dis. 2012 Jun;15(2):189-94. doi: 10.1038/pcan.2011.59. Epub 2011 Nov 29. Erratum in: Prostate Cancer Prostatic Dis. 2012 Jun;15(2):211. Cited in PubMed; PMID 22343837.

Pulido J, McMahon P, Treat JR, Gunselman J, Tasian GE, Tasian SK. Labial ecthyma gangrenosum in an immunocompromised infant with leukemia: heightening awareness for the urologist. Urology. 2012 Dec;80(6):1366-8. doi: 10.1016/j.urology.2012.08.020. Epub 2012 Oct 2. Cited in PubMed; PMID 23040328.

Glass AS, Bagga HS, Tasian GE, Fisher PB, McCulloch CE, Blaschko SD, McAninch JW, Breyer BN. Pubic hair grooming injuries presenting to U.S. emergency departments. Urology. 2012 Dec;80(6):1187-91. doi: 10.1016/j.urology.2012.08.025. Epub 2012 Oct 4. Cited in PubMed; PMCID: PMC3559025.

Tasian GE, Ziemba J, Casale P. Unilateral hypercalciuria: a stealth culprit in recurrent ipsilateral urolithiasis in children. J Urol. 2012 Dec;188(6):2330–5. doi: 10.1016/j.juro.2012.08.035. Epub 2012 Oct 22. Cited in PubMed; PMID 23088966.

Tasian GE, Cooperberg MR, Cowan JE, Keyashian K, Greene KL, Daniels NA, et al. Prostate specific antigen screening for prostate cancer: knowledge of, attitudes towards, and utilization among primary care physicians. Urol Oncol. 2012 Mar-Apr;30(2):155-60. doi: 10.1016/j.urolonc.2009.12.019. Epub 2010 Aug 25. Cited in PubMed; PMID 20800514.

Hsieh MH, Eisenberg ML, Hittelman AB, Wilson JM, Tasian GE, Baskin LS. Caucasian male infants and boys with hypospadias exhibit reduced anogenital distance. Hum Reprod. 2012 Jun;27(6):1577–80. doi: 10.1093/humrep/des087. Epub 2012 Mar 20. Cited in PubMed; PMID 22434852.

Qiao L, Tasian GE, Zhang H, Cao M, Ferretti M, Cunha GR, Baskin LS. Androgen receptor is overexpressed in boys with severe hypospadias, and ZEB1 regulates androgen receptor expression in human foreskin cells. Pediatr Res. 2012 Apr;71(4 Pt 1):393-8. doi: 10.1038/pr.2011.49. Epub 2012 Jan 6. Cited in PubMed; PMCID: PMC3423458.

2011

Tasian GE, Copp HL, Baskin LS. Diagnostic imaging in cryptorchidism: utility, indications, and effectiveness. J Pediatr Surg. 2011 Dec;46(12):2406-13. doi: 10.1016/j.jpedsurg.2011.08.008. Cited in PubMed; PMID 22152893.

Yiee JH, Tasian GE, Copp HL. Management trends in prenatally detected hydronephrosis: national survey of pediatrician practice patterns and antibiotic use. Urology. 2011 Oct;78(4):895-901. doi: 10.1016/j.urology.2011.04.027. Epub 2011 Jun 21. Cited in PubMed; PMCID: PMC3184201.

Tasian GE, Yiee JH, Copp HL. Imaging use and cryptorchidism: determinants of practice patterns. J Urol. 2011 May;185(5):1882-7. doi: 10.1016/j.juro.2010.12.065. Epub 2011 Mar 21. Cited in PubMed; PMID 21421239.

Qiao L, Tasian GE, Zhang H, Cunha GR, Baskin L. ZEB1 is estrogen responsive in vitro in human foreskin cells and is over expressed in penile skin in patients with severe hypospadias. J Urol. 2011 May;185(5):1888-93. doi: 10.1016/j.juro.2010.12.066. Epub 2011 Mar 21. Cited in PubMed; PMCID: PMC3428058.

Tasian GE, Copp HL. Diagnostic performance of ultrasound in nonpalpable cryptorchidism: a systematic review and meta-analysis.  Pediatrics. 2011 Jan;127(1):119-28. doi: 10.1542/peds.2010-1800. Epub 2010 Dec 13. Cited in PubMed; PMCID: 21149435.

Posters and Presentations

Posters

2020

Bowen DK, Song L, Faerber J, Kim J, Scales CD, Tasian GE: Retreatment after ureteroscopy and shockwave lithotripsy: A population-based comparative effectiveness study. Journal of Urology 203(6): 1156-1162, June 2020 Notes: Epub Mar. 24, 2020.

Shah AA, Carey RM, Brant JA, Tasian GE, Ziemba JB. An Analysis of the US News & World Report Methodology for Attribution of Specialty Care in Otolaryngology and Urology [published online ahead of print, 2020 Jul 21]. Otolaryngol Head Neck Surg. 2020;194599820941016. doi:10.1177/0194599820941016

Rubin D, Huang J, Fisher BT, Gasparrini A, Tam V, Song L, Wang X, Kaufman J, Fitzpatrick K, Jain A, Griffis H, Crammer K, Morris J, Tasian GE. Association of Social Distancing, Population Density, and Temperature With the Instantaneous Reproduction Number of SARS-CoV-2 in Counties Across the United States. JAMA Netw Open. 2020;3(7):e2016099. Published 2020 Jul 1. doi:10.1001/jamanetworkopen.2020.16099

2019

Zheng Q, Furth SL, Tasian GE, Fan Y: Computer-aided diagnosis of congenital abnormalities of the kidney and urinary tract in children based on ultrasound imaging data by integrating texture image features and deep transfer learning image features. Journal of Pediatric Urology 15(1): 75.e1-75.e7, Feb. 2019.

Chu DI, Abraham AG, Tasian GE, Denburg MR, Ross ME, Zderic SA, Furth SL: Urologic care and progression to end-stage kidney disease: a Chronic Kidney Disease in Children (CKiD) nested case-control study. Journal of Pediatric Urology 15(3): 266.e1-266.e7, Mar. 2019.

Tasian GE, Ross M, Song L, Audrain-McGovern J, Wiebe D, Warner SG, Henderson B, Patel A, Furth SL: Ecological momentary assessment of factors associated with water intake among adolescents with kidney stone disease. The Journal of Urology 201(3): 606-614, Mar. 2019.

Lawman HG, Lofton X, Grossman S, Root M, Perez M, Tasian G, Patel A: A randomized trial of a multi-level intervention to increase water access and appeal in community recreation centers. Contemporary Clinical Trials 79: 14-20, Apr. 2019.

Yin S, Zhang Z, Li H, Peng Q, You X, Furth SL, Tasian GE, Fan Y: Fully-automatic segmentation of kidneys in clinical ultrasound images using a boundary distance regression network. Proceedings. IEEE International Symposium on Biomedical Imaging 2019: 1741-1744, Apr 2019.

Lee AS, McGarry L, Bowen DK, Tasian GE: Patient characteristics associated with completion of 24-hour urine analyses among children and adolescents with nephrolithiasis. Urology 127: 102-106, May 2019.

Yin S, Peng Q, Li H, Zhang Z, You X, Liu H, Fischer K, Furth SL, Tasian GE, Fan Y: Multi-instance deep learning with graph convolutional neural networks for diagnosis of kidney diseases using ultrasound imaging. Uncertainty for Safe Utilization of Machine Learning in Medical Imaging & Clinical Image-based Procedures 11840: 146-154, Oct. 2019 Notes: Epub Oct. 7, 2019.

Bernard J, Song L, Henderson B, Tasian GE: Association between daily water intake and 24-hour urine volume among adolescents with kidney stones. Urology Jan. 28 2020 (Epub) Notes: doi: 10.1016/j.urology.2020.01.024.

Denburg MR, Koepsell KG, Lee JJ, Gerber J, Bittinger K, Tasian GE: Perturbations of the gut microbiome and metabolome in children with calcium oxalate kidney stone disease. Journal of the American Society of Nephrology May 7 2020 (Epub) Notes: doi: 10.1681/ASN.2019101131.

Ellison JS, Tasian GE: The impact of sex and gender on clinical care and research design in nephrolithiasis. Urology May 5 2020 (Epub) Notes: doi: 10.1016/j.urology.2020.04.089.

Yin S, Peng Q, Li H, Zhang Z, You X, Fischer K, Furth SL, Fan Y, Tasian G: Multi-instance deep learning of ultrasound imaging data for pattern classification of congenital abnormalities of the kidney and urinary tract in children. Urology 2020 (in press).

Lawman HG, Grossman S, Lofton X, Tasian G, Patel AI: Hydrate Philly: An intervention to increase water access and appeal in recreation centers. Preventing Chronic Diseases 17: E15, Feb. 20 2020.

Vicedo-Cabrera AM, Goldfarb DS, Kopp RE, Song L, Tasian GE: Sex differences in the temperature dependence of kidney stone presentations: A population-based aggregated case-crossover study. Urolithiasis 48(1): 37-46, Feb. 2020 Notes: Epub Mar. 21, 2019.

Yin S, Peng Q, Li H, Zhang Z, You X, Fischer K, Furth SL, Tasian GE, Fan Y: Automatic kidney segmentation in ultrasound images using subsequent boundary distance regression and pixelwise classification networks. Medical Image Analysis 60: 101602, Feb. 2020 Notes: Epub Nov. 8, 2019.

2018

Zheng Q, Tasian G, Fan Y: Transfer learning for diagnosis of congenital abnormalities of the kidney and urinary tract in children based on ultrasound imaging data. Proceedings: IEEE International Symposium on Biomedical Imaging 2018: 1487-1490, Apr. 2018 Notes: Epub May 24, 2018.

Lee AS, Bowen DK, Vatsky S, Zderic SA, Tasian GE: Percutaneous nephrolithotomy in an 8-week-old infant. Canadian Journal of Urology 25(3): 9363-9365, June 2018.

Tasian GE, Jemielita T, Goldfarb DS, Copelovitch L, Gerber JS, Wu Q, Denburg MR: Oral antibiotic exposure and kidney stone disease. Journal of the American Society of Nephrology 29(6): 1731-1740, June 2018 Notes: Epub May 10, 2018.

Kurtzman JT, Song L, Ross ME, Scales CD Jr., Chu DI, Tasian GE: Urology consultation and emergency department revisits for children with urinary stone disease. Journal of Urology 200(1): 180-186, July 2018 Notes: Epub Feb. 21, 2018.

Zheng Q, Warner S, Tasian G, Fan Y: A dynamic graph cuts method with integrated multiple feature maps for segmenting kidneys in 2D ultrasound images. Academic Radiology 25(9): 1136-1145, Sept. 2018 Notes: Epub Feb. 12, 2018.

Chu DI, Tan JM, Mattei P, Simpao AF, Costarino AT, Shukla AR, Rossano JW, Tasian GE: Outcomes of laparoscopic and open surgery in children with and without congenital heart disease. Journal of Pediatric Surgery 53(10): 1980-1988, Oct. 2018.
 

2017

Chu DI, Tan JM, Mattei P, Costarino AT, Rossano JW, Tasian GE: Mortality and morbidity after laparoscopic surgery in children with and without congenital heart disease. Journal of Pediatrics 185: 88-93.e3, June 2017 Notes: (Epub Mar. 3, 2017).

Denburg MR, Leonard MB, Jemielita TO, Golden NH, Tasian G, Copelovitch L: Risk of urolithiasis in anorexia nervosa: A population-based cohort study using the Health Improvement Network. European Eating Disorders Review: the Journal of the Eating Disorders Association 25(5): 406-410, Sept. 2017.

Ross ME, Vicedo-Cabrera AM, Kopp RE, Song L, Goldfarb DS, Pulido J, Warner S, Furth SL, Tasian GE: Assessment of the combination of temperature and relative humidity on kidney stone presentations. Environmental Research 162: 97-105, Apr. 2018 Notes: (Epub Dec. 28, 2017).

2016

Tasian GE, Ross ME, Song L, Warner S, Grundmeier R, Massey J, Chi T, Killilea DW, Stoller ML, Furth SL: Dietary zinc is inversely associated with risk of nephrolithiasis in adolescents. Moderated poster presentation, American Urological Association Annual Meeting, San Diego, CA May 2016.

Tasian GE, Ross ME, Song L, Furth SL: Temporal trends in direct costs of nephrolithiasis, 2001-2012. Moderated poster presentation, American Urological Association Annual Meeting, San Diego, CA May 2016.

Tasian GE, Ross ME, Gasparrini A, Kopp R, Song L, Furth SL : Age differences in the temperature dependence of kidney stone presentation. Moderated poster presentation, American Urological Association Annual Meeting, San Diego, CA May 2016.

Tasian GE, Kabarriti A, Kalmus A, Furth SL: 24-hour urine analyses and kidney stone recurrent in children and adolescents" Moderated poster presentation, American Urological Association Annual Meeting, San Diego, CA May 2016.

2015

Tasian GE, Ross ME, Song L, Keren R, Chu DI, Saigal CS, Furth SL: Annual incidence of nephrolithiasis among children and adults in South Carolina from 1997 to 2012: a repeated cross-sectional study. Moderated poster, American Urological Association Annual Meeting, New Orleans, LA May 2015.

Tasian GE, Kalmus A, Furth S: Kidney stone recurrence among children and adolescents. Moderated poster, American Urological Association Annual Meeting, New Orleans, LA May 2015.

Tasian GE, Fischer K, Li C, Wang H, Furth SL: Normalized renal parenchymal area from birth to 10 months. Podium presentation, American Urological Association Annual Meeting, New Orleans, LA May 2015.

Lectures by Invitation

2016

Tasian G. Pediatric Kidney Stone Disease: A Modern Epidemic and the Missing Microbe. University of California, San Francisco Department of Urology;  2016 Oct; San Francisco, CA.

Tasian G. Pediatric Urinary Stone Disease: A Lifetime of Risk and Opportunity. University of California, San Francisco Department of Urology; 201 Oct; San Francisco, CA.

Tasian G. The Emergence of Nephrolithiasis as a Disease of Childhood. United States Navy, Department of Urology; 2016 May; San Diego, CA.

Tasian G. Comparative Effectiveness of Ureteroscopy and Shock Wave Lithotripsy for Children. United States Navy, Department of Urology; 2016 May; San Diego, CA.

Tasian G. Management of Urinary Tract Infection: Updates from Recent Randomized Trials. Rutgers University; St. Peter's Hospital 2016 Feb; New Brunswick NJ.

Tasian G. Nephrolithiasis during Childhood: Epidemiology, Evaluation, and Secondary Prevention. Rutgers University; St. Peter's Hospital; 2016 Feb. New Brunswick NJ.

Tasian G. Anatomic Biomarkers of Chronic Kidney Disease Progression in Children. Center for Biomedical Image Computing and Analytics. University of Pennsylvania; 2016 Jan; Philadelphia, PA.

2015

Tasian G. New Population at Risk: Extra-renal disease in Pediatric Nephrolithiasis" State University of New York, Downstate; 2015 Sep; New York, NY.

Tasian G. Changing Epidemiology of Nephrolithiasis: Implications for Children and Adolescents. Columbia University, Department of Urology; 2015 Jul; New York, NY.

Tasian G. Temperature-Dependence of Kidney Stone Presentation: Mitigating Risk by Changing Behavior"; University of Michigan, Department of Urology, Division of Health Services Research; 2015 Jun; Ann Arbor, MI.

Tasian G. Unique Challenges in Pediatric Urinary Stone Disease"; Urinary Stone Disease: Research Challenges and Opportunities. National Institutes of Health; 2015 Apr; Bethesda, MD.

Tasian G. Temperature Dependence of Kidney Stone Presentation" Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania; 2015 Feb; Philadelphia, PA.

Tasian G. Pediatric Kidney Stones: What's Behind the Increase and How to Treat. Lancaster General Hospital; 2015 Jan; Lancaster, PA.

Awards and Honors

2019, Basic Science Prize, Societies for Pediatric Urology (SPU). American Urological Association Annual Meeting, Chicago, IL

2017, Election to membership, Research on Calculus Kinetics (ROCK) Society (research honor society)

2017, Third Place, AUA Young Investigator Award Presentation, "Association Between Oral Antibiotics and Incident Kidney Stones." American Urological Association Annual Meeting, Boston, MA

2016, University of Pennsylvania Institute of Translational Medicine and Therapeutics Incentive Based Translational Science Grant (NIH/NCATS UL1TR000003)

2016, American Society for Clinical Investigation (ASCI) Young Physician-Scientist Award

2016, Principal Investigator, Urinary Stone Disease Research Network (NIH/NIDDK U01DK110961)

2015, K23 Mentored Patient-Centered Research Career Development Award

2014, Society of Pediatric Urology (SPU) Research Grant

2014, Outstanding Patient Oriented Research Presentation; 24rd annual Children's Hospital of Philadelphia Research Poster Day

2013, Urologic Diseases in American Project Collaborator

2013, Center for Pediatric Clinical Effectiveness (CPCE) Pilot Grant Award

2013, Outstanding Patient Oriented Research Presentation; 23rd annual Children's Hospital of Philadelphia Research Poster Day

2013, Best Poster Award, International Pediatric Nephrology Association (Shanghai, China)

2012, Outstanding Patient Oriented Research Presentation; 22nd annual Children's Hospital of Philadelphia Research Poster Day

2012, Second place, Resident Essay Competition, Philadelphia Urological Society

2011, UCSF Clinical and Translational Science Institute Resident Research Training Program Travel Award

2010, First place, UCSF Clinical and Translational Science Institute Research Symposium

2010, California Urology Foundation Research Grant

2009, Second place (Clinical Research); Northern California Urological Resident Research Symposium

2005, DeBakey Scholar (awarded to top student in medical school class)

2005, Summa cum laude, Baylor College of Medicine

2003, Alpha Omega Alpha (elected junior year)

2002, Baylor College of Medicine Scholar

2002, McGraw-Hill/Lange Medical Student Book Award

2000, Summa cum laude, Trinity University

1999, Phi Beta Kappa (elected junior year)

1997, Men's Swimming NCAA conference finalist

1996, Trinity University President's Scholar

Editorial and Academic Positions

Editorial Board

2019-Present Academic Editor, PLOS ONE

2018-Present Section Editor for Urology, Current Pediatrics Reports

2016-present, American Journal of Kidney Diseases

2016-Present, Editorial Board, American Journal of Kidney Diseases

Reviewer

2015-present, Pediatric Nephrology

2015-present, Journal of the Pediatric Infectious Disease Society

2015-present, PLOS One

2015-present, International Journal of Biometerology

2015-present, Urolithiasis

2015-present, Value in Health

2014-present, New England Journal of Medicine

2013-present, Clinical Journal of the American Society of Nephrology

2013-present, JAMA- Pediatrics

2012-present, The Journal of Pediatric Urology

2012-present, Referee, Cochrane Database of Systematic Reviews (Cryptorchidism)

2012-present, Journal of Endourology

2012-present, Organizer of Section on Population and Health Services Research, The Journal of Pediatric Urology

2011-present, Archives of Pediatrics and Adolescent Medicine

2011-present, Pediatrics

2010-present, The Journal of Urology

Leadership and Memberships

2020-Present,  NIH/NIDDK Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (Special Emphasis Review Panel)
2019-Present, NIH/NIDDK Urologic and Urogynecologic Applications Special Emphasis Panel (Study Section)
2019-Present, Urologic Diseases in America (UDA) Compendium Project, National Institutes of Health (Technical Review Panel)
2018-Present, Hyperoxaluria Foundation (Scientific Advisory Board) 2018-Present Oxalosis & Hyperoxaluria Foundation (Scientific Advisory Committee (SAC), 2018)
2018-2019, Rare Kidney Stone Consortium (External Advisory Council)
2017-Present, American Urological Association National Urology Research Agenda (NURA) (Committee Member, Nephrolithiasis Section)
2017-Present, Urology Care Foundation Patient Education (Pediatric Health Committee)
2015-Present, Planning Committee Member and Speaker, NIDDK Urinary Stone Disease Meeting
2014-present, Society of University Urologists (SUU)
2014-present, American Medical Association (AMA)
2014-present, American College of Surgeons (ACS)
2013-present, American Urological Association Cryptorchidism Guideline Panel
- Scientific Committee
2013-present, International Consultation on Urologic Diseases
- Genital Malformations Guideline Committee
- Scientific Committee
2011-present, Society for Pediatric Urology (SPU)
2007-present, American Urological Association (AUA)