3rd Annual Immune Dysregulation Symposium: Precision Medicine for Immunological Disorders

Jun 4, 2021 from 8:30 a.m. - 4 p.m. (ET)

Precision Medicine for Immunological Disorders will be a unique and illuminating symposium by international experts, including those from the Immune Dysregulation Program at Children's Hospital of Philadelphia. Keynote speakers include Mark M. Davis, PhD, Director of Stanford Institute for Immunity, Transplantation and Infection, and Jean-Laurent Casanova, MD, PhD, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at the Rockefeller University. Speakers will detail recent advances in precision medicine for children with immunological disorders and the basic science behind these approaches. This full-day event is open to clinicians, researchers and others who care for patients with complex multi-organ immune diseases. In this seminar, attendees will gain an understanding of:

  • How to leverage cytokine or other multiplex immune assays to make patient decisions
  • Effective use of novel immune modulator therapeutics
  • How to use genetic data to make diagnoses and predict how a patient may respond to certain treatments


  • 8:00-8:30 a.m. – Registration
  • 8:30-8:35 a.m. – Welcome and Introduction (Ed Behrens)
  • 8:35-9:05 a.m. – CHOP Immune Dysregulation Approach to Precision Medicine (Ed Behrens)
  • 9:05-9:35 a.m. – ImmuneHealth: Querying the Immune System in Health and Disease (John Wherry)
  • 9:35-10:05 a.m. – Precision Medicine and Diagnostics in Sepsis (Fran Balamuth)
  • 10:05-10:15 a.m. – BREAK
  • 10:15-11:15 a.m. – Keynote 1: Genetic and immunological causes of life-threatening COVID-19 (Jean Laurent Casanova)
  • 11:15-11:45 a.m. – Antibiotic discovery by means of computers (Cesar de la Fuente)
  • 11:45 am-12:00 p.m. - BREAK
  • 12:00-12:30 p.m. – Lunch case presentation 1: Ehrlichia-induced Hemophagocytic Lymphohistiocytosis (Bill Otto)
  • 12:30-1:00 p.m. – Lunch case presentation 2: Secondary HLH in CGD (Di (Sandy) Sun)
  • 1:00-1:30 p.m. – VEO-IBD: A Model For a Precision Medicine Approach (Judith Kelsen)
  • 1:30-2:00 p.m. – Perforin 2 pokes its way into IL-33 biology (De’broski Herbert)
  • 2:00-2:30 p.m. – Position and Trajectory in Autoinflammatory Space (Scott Canna)
  • 2:30-2:45 p.m. - BREAK
  • 2:45-3:45 p.m. – Keynote 2: Enabling Human Immunology: A Direct Connection Between Infectious Diseases and Autoimmunity (Mark Davis)
  • 3:45-4:00 p.m. – Closing Remarks (Ed Behrens)

Register now


Adriana Deverlis

(614) 370-9246


ACCME Accreditation Statement: Children’s Hospital of Philadelphia is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement: Children's Hospital of Philadelphia designates this live activity for a maximum of 7.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.