Over the past 20 years, advances in prenatal diagnosis have led to the development of fetal therapies to treat congenital anomalies. The current fetal interventions employ surgical approaches to correct anatomical defects in-utero, with the goal of improving survival and decreasing associated morbidities. While these treatments have proven successful, clinical indications remain limited. Fetal stem cell and gene therapy have the potential to treat multiple inherited disorders, and could significantly expand the use of fetal intervention to a wide range of congenital disorders.
This enduring material continuing education activity is intended to meet the educational needs and practice skills of physicians, advanced practice nurses, nurses, researchers, and other healthcare professionals in the fields of maternal fetal medicine, obstetrics, radiology, genetics, neonatology, pediatric surgery, urology, pediatrics, anesthesiology and family practice.
Upon completion of this enduring material, participants will be able to:
- Discuss the rationale of prenatal stem cell and gene therapy for the treatment of congenital disorders
- Review the history and experimental progress toward clinical application of these treatments
- List potential disorders for which stem cell and gene therapy show the greatest potential for clinical use
- Cite current limitations of each treatment
AMA Credit Designation Statement
The Children’s Hospital of Philadelphia designates this enduring material for a maximum 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Advanced Practice Nurse and Registered Nurse Participation
Advanced practice providers (APP), nurses and respiratory therapists who complete this enduring material educational activity will need to follow the instructions in the “Method of Participation” section and will be eligible to receive a certificate of completion, which may be used for re-licensure and re-certification. For further information, please contact Kathleen Monforto, PhD, MSN, RN, CPN, Education Nurse Specialist, at firstname.lastname@example.org.