Neuropsychological Late Effects of Pediatric Cancer Treatment

Oct 22, 2021 from 8 a.m. - 9 a.m. (ET)

Globally, over 300,000 children are diagnosed with cancer annually. Treatments continue to improve, and children and adolescents are surviving at higher rates. Nonetheless, morbidities of cancer and treatment persist. This includes altered trajectories of cognitive development, executive functions, processing speed, visual-spatial skills, and mood. While those who have experienced a pediatric brain tumor are at greatest risk for neuropsychological late effects, those diagnosed with hematological malignancies or solid organ tumors also experience late effects of cancer and therapies. The team at CHOP has a multitiered surveillance and intervention model to monitor for neuropsychological late effects in accordance with the Standards for the Psychosocial Care of Children With Cancer and Their Families.

In this lecture a CHOP expert in late effects will:

  • Discuss how treatments such as radiation therapy, chemotherapy, transplant, and immunotherapy impact child development
  • Highlight the importance of early detection of emerging challenges
  • Emphasize the individual risks and resiliencies that contribute to outcomes
  • Recognize the supports that help children and families thrive at home and in their community


Learning objectives

  1. Discuss how various diagnoses, treatments, and demographic and environmental factors contribute to neuropsychological functioning.
  2. Review the multiple domains of neuropsychological abilities, and how these domains impact educational, vocational, and social outcomes.
  3. Identify supports and interventions that improve neuropsychological functioning and quality of life.



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ACCME Accreditation Statement: Children’s Hospital of Philadelphia is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Approval of AMA PRA Category 1 Credit(s) for this lecture is pending. If approved, physicians can claim CME credit commensurate with the extent of their participation in the activity for free.

Related specialties: oncology, hematology, neurology, general pediatrics