Transforming Children’s Health Through Research

Your support for CHOP Research Institute makes groundbreaking discoveries possible, fueling new therapies, guiding clinical care, and creating brighter futures for children in need. Every breakthrough we achieve begins with the generosity of donors who believe in the power of research to transform lives.

Donate Now

Breakthroughs Begin Here

At CHOP, research isn’t an add-on; it’s the engine behind every breakthrough in care. From the lab bench to the child’s bedside, our investigators work across disciplines to focus on the most urgent and complex challenges in children’s health. Every discovery is guided by a singular mission: to improve the lives of children everywhere. Fueled by curiosity and compassion, our scientists turn bold ideas into transformative solutions—breakthroughs that shape and change pediatric medicine.

Why CHOP?

Researchers at CHOP have been creating brighter futures for children for more than a century
Home to breakthroughs like the first FDA-approved gene therapy for a pediatric genetic disorder
Deep integration of science and clinical care—what we discover today can save lives tomorrow
State-of-the-art technologies, strong partnerships, and a world-class academic medical research community
Incredible breadth and depth of research innovation where world experts in common and complex pediatric disorders collaborate to find solutions that help children thrive

View our interactive timeline

‘Breakthrough’ Phase 3 Study Changes Standard of Care for Childhood B-cell Leukemia

Gene Therapy for Sickle Cell Disease Offers Patient New Lease on Life

In Landmark Study, CHOP-Penn Team Treats Newborn With Base-Editing Therapy

Partner with Us to Fuel the Next Breakthrough

Your generosity fuels discovery

When you support research at CHOP, you become part of every discovery and every life it touches. Whether you give to the greatest needs or a field that’s personal to you, your generosity drives progress for children everywhere. Breakthroughs can’t wait and your support today accelerates the discoveries children need now. Join us in shaping the future of children’s health.

Ways to Give

Support the Research Institute

Invest in the driving force behind every discovery. A gift to the CHOP Research Institute helps advance bold, high-impact science across all areas of pediatric medicine. From revolutionary gene therapies to breakthroughs in mental health, cancer and rare diseases, your support fuels the infrastructure, technology and talent that power lifesaving innovation. With your partnership, our scientists can pursue bold ideas and bring new solutions to children faster. Your gift helps accelerate research, launch clinical trials, and bring healing and hope to children and families facing serious challenges.

Designate Your Gift

Support the breakthroughs that matter most to you. Whether your passion lies in oncology, neuroscience, behavioral health or another area of child health, CHOP offers meaningful opportunities to direct your philanthropy.

Contact

If you would like to learn more about how you can support CHOP Research Institute or explore opportunities to align your philanthropy with the breakthroughs that matter most to you, please contact Doug Kleintop at:

kleintopd@chop.edu

“Philanthropy fuels the breakthroughs that change lives. We’re deeply grateful to our donors for their vision, generosity and belief in our mission to transform the future of children’s health.” – Sue Furth, MD, PHD, Executive Vice President and Chief Scientific Officer