Marilyn Li Laboratory

The Li Laboratory, led by Marilyn M. Li, MD, specializes in the genomic analysis of pediatric tumors using state-of-the-art technology, such as next-generation sequencing, and other genomic tools. The driving force behind their research is the identification of mutations and signature genomic sequences that will aid in cancer diagnosis, measure disease progression, and optimize treatment strategies for children with cancer.

Ongoing Research

Selected Publications

Breast adenocarcinoma recurring as small cell carcinoma in a patient with a germline BRCA2 mutation: Clonal evolution unchecked. Exp Hematol Oncol. 2015 Jan 6;4(1):1. doi: 10.1186/2162-3619-4-1. eCollection 2015.
P. Niravath T, Eble A, Contreras L, Franco M, Li M, Rimawi MF.

p53 enables metabolic fitness and self-renewal of nephron progenitor cells. Development. 2015 Apr 1;142(7):1228-41. doi: 10.1242/dev.111617.
Li Y, Liu J, Li W, Brown A, Baddoo M, Li M, Carroll T, Oxburgh L, Feng Y, Saifudeen Z. 

Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial. J Clin Pathol. 2015 Feb;68(2):111-8. doi: 10.1136/jclinpath-2014-202644. Epub 2014 Nov 27. 
Kapp JR, Diss T, Gandy M, Spicer J, Schrijver I, Jennings LJ, Li M, Tsongalis GJ, Gonzalez de Castro D, Bridge J, Wallace A, Hing S, Deignan J, Butler R, Verghese E, Latham GJ, Hamoudi RA.