Standardizing Treatment of Children with Polyarticular Juvenile Idiopathic Arthritis to Improve Outcomes

Published on in CHOP News

Stylized child iconImprove Outcomes
Smiley face iconReduce Suffering
Clipboard with checkmarkIncrease Effectiveness and Efficiency

Why is this important?

Children’s Hospital of Philadelphia (CHOP) treats approximately 500 children with juvenile idiopathic arthritis (JIA). Polyarticular JIA (Poly-JIA) is a severe subtype that can cause joint damage, poor growth and development, limited mobility, and pain. There is significant variation in how rheumatologists approach the evaluation and treatment of patients with Poly-JIA, which can impact outcomes.  

What we did

Our multidisciplinary rheumatology team created a “treat to target” approach by standardizing how we evaluate and treat patients with Poly-JIA. We designed a database to document disease activity and made sure that physicians reviewed a standard disease activity score at each visit. We created algorithms to help doctors consistently provide optimal treatment for our patients with Poly-JIA throughout the disease course. The team also documented whether disease activity was “at target.”


We reduced Poly-JIA disease activity by one-third, which reduced the need to perform steroid joint injections.

Graph: Average JADAS Score.

Updated May, 2020


Next Steps

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