News Room

CHOP Researchers Discover Deep Structural Biology Connections that Help Improve CAR Therapy

Published on Dec 01, 2023

Identifying “backbones” that link complexes can help maximize CAR therapy across different variants and tumor types.

Children’s Hospital of Philadelphia’s Center for Violence Prevention Marks Major Milestone

Published on Nov 29, 2023

Today, Children’s Hospital of Philadelphia’s Center for Violence Prevention (CVP) marks a major milestone -- 10 years of unified programming and research focused on reducing exposure to and impact of violence on youth and their families.

Researchers Identify Three Genes Associated with Neurodevelopmental Disorders

Published on Nov 28, 2023

All three genes had variants affecting splicing and resulted in symptoms like developmental delays, intellectual disability, hypotonia, seizures and autism.

CHOP Researchers Define Seizure Burden, Developmental Outcomes for STXBP1-Related Disorders

Published on Nov 28, 2023

This major step allows for the creation of clinical trials to test key endpoints that will determine the efficacy of new therapies.

CHOP Researchers Use Human Stem Cells to Model a Severe Epilepsy Syndrome and Identify a Potential Targeted Treatment

Published on Nov 21, 2023

An experimental compound might be further developed as an effective treatment approach for affected patients.

CHOP Hematologist Honored by American Society of Hematology for Leadership in Promoting Diversity

Published on Nov 20, 2023

Alexis Thompson, MD, MPH, received the award at the society’s annual meeting.

Got Milk? How Pasteurized Donor Human Milk Helps Babies Thrive

Published on Nov 17, 2023

Shortly after giving birth at Thomas Jefferson University Hospital, Meredith Alley found herself visiting her son, Graham, in the neonatal intensive care unit (NICU). He had arrived earlier than expected and faced respiratory distress that required special care.

Children’s Hospital of Philadelphia Receives Multi-Million Dollar Gift from Holveck Family to Support Groundbreaking Osteosarcoma Research

Published on Nov 16, 2023

Children’s Hospital of Philadelphia (CHOP) has received a $6.4 million gift from the family of Connor Boyle, a Central Bucks East High School graduate who died at age 18 from osteosarcoma. This three-year gift, named The Connor Initiative: Precision Therapeutics for Osteosarcoma & Rare Cancers, will support cutting-edge research in osteosarcoma and other rare cancers.

Gene Splicing Reduces Effectiveness of CD20-Targeting Monoclonal Antibodies Designed to Treat Variety of Blood Cancers and Disorders

Published on Nov 16, 2023

Researchers found CAR T-cell therapy may serve as effective alternative for patients with these disorders.

CHOP Researchers Find Racial, Neighborhood Disparities in Pediatric Cardiac Arrest

Published on Nov 13, 2023

 In an abstract presented at AHA, researchers found Black children are more than four times as likely to experience cardiac arrest and have significantly worse survival outcomes.