Advancing game-changing research that saves children’s lives is paramount to our mission at Children’s Hospital of Philadelphia (CHOP). With more than 160 years of innovation behind us, our researchers are on the cusp of countless new discoveries, therapies and devices that will transform children’s lives. We will work to ensure that every child has the chance to grow into a healthy adulthood.

Why Give Now?

With your help, we will raise $400 million to move breakthroughs from the lab to clinic, where they can help children and families. Our researchers are harnessing the power of genomics and big data to figure out what causes pediatric diseases and then target treatments accordingly.

What We Can Accomplish Together

Your support through this campaign will help CHOP change the landscape of pediatric research as we enter the next decade.

A Breakthrough in Leukemia Treatment

After years of grueling, yet unsuccessful, treatment for leukemia, Emily Whitehead and her family arrived at Children’s Hospital of Philadelphia. It seemed they were out of options.

Under the care of Stephan Grupp, MD, PhD, Director of the Cancer Immunotherapy Program, the Whiteheads bravely allowed Emily to become the first child to receive an experimental CAR T-cell therapy, which reprograms the T cells in the body’s immune system to fight a certain type of relapsed acute lymphoblastic leukemia (ALL).

Since then, the results have been unprecedented, with a complete remission rate of 90 percent on the pilot clinical trial. Emily herself is more than five years out from this CAR T-cell treatment. Dr. Grupp was lead investigator of the CHOP and global trials of the therapy, which is now FDA approved for use in certain leukemia patients up to 25 years of age.