Inflammatory Bowel Disease Publications and Presentations

2016

Picoraro J, Winberry G, Siegel C, El-Matary W, Moses J, Grossman AB, Park KT: Premedication Use Prior to Infliximab Administration: A Cross-Sectional Analysis from the Clinical Care and Quality and Inflammatory Bowel Disease Committees of NASPGHAN. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Kerur B, Machan JT, Cerezo C, Markowitz J, Mack DR, Griffiths AM, Otley AR, Pfefferkorn MD, Rosh JR, Keljo DJ, Crandall WV, Rick J, Noe J, Oliva-Hemker M, Kay MH, Saeed SA, Grossman AB, Sudel B, Kappelman M, Schaefer M, Faubion W, Tomer G, Deslandres C, Morganstern J, Bousvaros A, Lerer T, Hyams JS, LeLeiko NS: Surgery in Pediatric Crohn's Disease 2002-2014. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Kelsen J, Dawany N, Conrad M, Piccoli D, Giraudo C, Behrens E, Sullivan K, Devoto M: "The role of the Hyperinflammatory Pathway in Very Early-Onset Inflammatory Bowel Disease. Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

Itkin M, Piccoli DA, Dori Y: "Protein-Losing Enteropathy:  Redefining the Anatomy and Pathophysiology and Providing Novel Therapy" Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

El-Matary W, Samson C, Ali S, Grossman AB: Rapid Infliximab Infusion in Children with Inflammatory Bowel Disease: A Multi-Center North American Experience. World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition, Montreal, Quebec October 2016.

Conrad M, Darwany N, Bittinger K, Baldassano RN, Piccoli DA, Bushman F, Devoto M, Kelsen J: "Characterization of the Intestinal Microbiome of Very Early Onset Inflammatory Bowel Disease" Poster Presentation at the World Congress of Pediatric Gastroenterology, Hepatology and Nutrition Meeting, Montreal, Canada October 2016.

Conrad MA, Dawany N, Bittinger K, Baldassano RN, Piccoli D, Bushman FD, Devoto M, Kelsen JR: Characterization of the Intestinal Microbiome in Very Early Onset Inflammatory Bowel Disease  Digestive Disease Week Annual Meeting, San Diego, CA May 2016.

Kelsen JR, Dawany N, Conrad, MA, Martinez A, Artis D, Sonnenberg GF, Mamula P, Piccoli DA, Baldassano RN, Sullivan KE, Devoto M: SU1851 Transcriptome Analysis Elucidates the Relevance of WES-Identified Variants in Patients with VEO-IBD. Gastroenterology 150(4): S570, April 2016.

Crawford JE.; Stevenson J.; Goldoor L.; Markowitz L.; Tucker M.; Novelli C.; Turner E.; Bogan G.; Driggers J.; Peck S.; Grossman AB.: The Multidisciplinary Inflammatory Bowel Disease (IBD) Education Model: An educational approach that crosses developmental and life stages of children & families living with IBD. National Association of Clinical Nurse Specialists Annual Meeting, Philadelphia, PA March 2016.

Plantz K, Stein R, Maxwell E, Mamula P, Baldassano RN.  Intravenous iron sucrose for treatment of iron deficiency anemia in pediatric inflammatory bowel disease.  2015 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 10-12, 2015; Inflamm Bowel Dis 22(S1):S1-S91, March 2016.  Oral and poster presentation.  Additional poster presentation at the 2016 Children’s Hospital of Philadelphia Research Poster Day, Feb 24, 2016, was presented the “Patient-Oriented Research Award”.

Kelsen J, Dawany N, Conrad M, Martinez A, Mamula P, Piccoli D, Artis D, Sonnenberg G, Baldassano RN, Sullivan K, Devoto M.  Understanding the relevance of whole exome sequencing identified variants in patients with very early-onset-IBD.  2015 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 10-12, 2015; Inflamm Bowel Dis 22(S1):S1-S91, March 2016. 

2015

Zeisler B, Lerer T, LeLeiko N, Bousvaros A, Rosh J, Grossman AB, Kay M, Faubion W, Kappelman M, Markowitz J, Sudel B, Rick J, Cabrera J, Boyle B, Oliva-Hemker M, Pfefferkorn M, Morganstern J, Saeed S, Otley A, Keljo D, Griffiths A, Mack D, Hyams J: Outcome Following Aminosalicylate Therapy in Children Newly Diagnosed with Crohn's Disease: A Prospective Multi-center Registry Experience. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Stein RE, Conrad MA, Maxwell EC, Albenberg LA, Baldassano RN, Dawany N, Grossman AB, Mamula P, Piccoli DA, Kelsen JR: Vedolizumab Therapy in Severe Pediatric Inflammatory Bowel Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Hoffman NJ, Maxwell EC, Piccoli DA, Grossman AB: ESR and CRP in Inflammatory Bowel Disease: Do We Need Both? North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Godwin B, Demuynck S, Maxwell E, Baldassano RN, Grossman AB, Kelsen JR, Albenberg L: Efficacy of Combination Antibiotic  Therapy for Refractory IBD at CHOP: A Single Center Case Series. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Adler J, Grossman AB, Israel EJ, Kim S, Saeed SA, Pratt JM, Collins J, Colletti R: Extent of Disease in Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Learning Health Network. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Washington, DC October 2015.

Yaeger R, Miller V, Kelsen JR, Wang K, Tang L, Kelsen D: Clinically relevant genomic alterations are frequent in Colitis Associated Cancers. ASCO May 2015.

Kelsen J, Albenberg L, Bailey A,  Bittinger K,  Schall1 J,  Mascarenhas M, Bushman FD, and Stallings G: 16S Gene Sequencing Reveals a Unique Bacterial Signature in the Gut Microbiota of Pediatric Patients with Cystic Fibrosis. Digestive Disease Week May 2015.

Kelsen J Dawany, N, Moran C, Winter D, Daly M, Rappaport E, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto, M: Autosomal recessive model of transmission in VEO-IBD using WES. Oral Abstract DDW May 2015.

Conrad M, Stein R, Maxwell EC, Albenberg L, Baldassano R, Grossman AB, Mamula P, Piccoli D, Delsen JR: The Use of Vedolizumab for Treatment of Severe Pediatric Inflammatory Bowel Disease. Digestive Disease Week, Washington, DC May 2015 Notes: Oral presentation by collaborator Stein R.

2014

Kelsen J, Moran C, Noor D, Pauly-Hubbard H, Rappaport E, Mamula P, Piccoli DA, Winter H, Daly M, Sonnenberg G, Artis D, Baldassano RN, Marcella D.  Digenic inheritance of primary immunodeficiency gene variants identified by whole exome sequence in very early onset IBD patients.  2014 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 4-6, 2014; Inflamm Bowel Dis 20():S9-S10, Dec 2014. Oral presentation.

Kelsen J  Dawany, N, Moran C, Winter D, Daly M, Rappaport E, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto, M: Digenic inheritance of primary immunodeficiency gene variants identified by whole exome sequence in VEO-IBD patients. Oral Abstract CCFA Dec 2014.

Cardinale C, Li J, Wei Z, Chang X, Baldassano RN, Hakonarson H.  Pathway-based genome-wide association study reveals an association between ErbB signaling and inflammatory bowel disease.  2014 Advances in Inflammatory Bowel Diseases: Crohn’s & Colitis Foundation’s Clinical & Research Conference, Orlando FL, Dec 4-6, 2014;

Turner D, Doveh E, Cohen A, Wilson D, Grossman AB, Rosh J, Lu T, Noble A, Baldassano RN, Levine A, Lerner A, Bousvaros A, Griffiths AM: Oral versus subcutaneous methotrexate in pediatric Crohn's disease: a multicenter propensity score study. UEG Week, Vienna, Austria October 2014.

Sahn B, De Matos, V, Ruchelli E, Masur S, Klink A, Baldassano RN, Piccoli, DA, Russo P, Mamula P.  A histological scoring system for ileitis in children with inflammatory bowel disease.  North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S34. Poster presentation.

Morganstern J, Lapsia S, Lerer T, Markowitz J, Griffiths A, Cabrera J, Mack D, Rick JR, Otley A, Pfefferkorn M, Rosh J, Kay M, Oliva-Hemker M, Saeed S, LeLeiko N, Carvalho R, Grossman AB, Keljo D, Sudel B, Kappelman M, Faubion W, Kugathasan S, Schaefer M, Tomer G, Deslandres C: Association of Being Overweight or Obese on Hospitalization, Surgeries, and Escalation of Medical Therapy in Inflammatory Bowel Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Atlanta, GA October 2014.

Maxwell E, Kelsen J: Sickle Cell Disease in Pediatric Patients with Inflammatory Bowel Disease: A case Series of Six Patients. NASPGHAN Annual Meeting, Poster Presentation, Atlanta, GA October 2014.

Lee R, Lerer T, Griffiths A, Pfefferkorn M, Otley A, Rick J, Mack D, Cabrera J, Rosh J, Bousvaros A, Kay M, Oliva-Hemker M, Saeed S, LeLeiko N, Grossman AB, Keljo D, Kappelman M, Faubion W, Deslandres C, Boyle B, Markowitz J, Hyams J: Durability of Adalimumab Therapy in Children with Crohn's Disease. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting, Atlanta, GA October 2014.

Lee D, Baldassano RN, Compher C, Albenberg L, Otley A, Griffiths A, Bushman F, Wu GD, Lewis JD.  Effectiveness of nutritional and anti-TNF therapy in North American children with active Crohn’s disease.  North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S37. Poster presentation.

Kelsen J, Moran C, Sasson A, Pauly-Hubbard H, Rappaport E, Mamula P, Piccoli D, Artis D, Sonnenberg G, Winter H, Baldassano RN, Devoto M.  Analysis of candidate genes by whole exome sequencing in very early-onset IBD. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2014 Annual Meeting, Atlanta GA, Oct 23-26, 2014; JPGN:59(S2),S147. Poster presentation. NASPGHAN Young Investigator Award.

Kelsen J, Dawany N, Moran C, Rappaport E, Winter H, Daly M, Mamula P, Piccoli P, Artis D, Sonnenberg G, Baldassano R, Sullivan K, Devoto M: Analysis of Candidate Genes in_ VEO-IBD. Oral Abstract, NASPGHAN 2014 Oct 2014.

Walters T, Faubion WA, Griffths A, Baldassano RN, Escher J, Ruemmele F, Hyams JS, Lazar A, Eichner S, Li Y, Pappalardo B, Thakkar RB.  Growth improvement in adalimumab-treated paediatric patients with Crohn’s disease: Data from Imagine 1.  3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation. 

Stein RE, Lee DY, Leonard MB, Thayu M, Herskovitz RM, Kerbowski T, Baldassano RN. The association between drug levels, anti-drug antibodies, and therapeutic response during infliximab therapy in pediatric Crohn disease. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation. 

Otley R, Lee DY, Baldassano RN, Griffths AM, Compher CW, Albenberg LG, Bushman FD, Wu GD, Lewis JD. Comparison of quality of life among children treated with nutritional and anti-TNF therapies for active Crohn’s disease in North America. 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Poster presentation.

Lee DY, Baldassano RN, Compher CW, Albenberg LG, Otley AR, Griffths AM, Bushman FD, Wu GD, Lewis JD.  Effectiveness of nutritional and anti-TNF therapy in North American children with active Crohn’s disease.  3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014), Rotterdam, The Netherlands, Sept 10-13, 2014. Oral presentation – accepted for Best Abstract. 

Markowitz J, Lerer T, Morganstern J, Deslandres C, Tomer G, Schaefer M, Kugathasan S, Faubion WA, Kappelman M, Sudel B, Hitch M, Keljo DJ, Grossman AB, Carvalho R, Leleiko NS, Saeed SA, Oliva-Hemker M, Kay MH, Rosh JR, Pfefferkorn MD, Otley AR, Rick J, Mack DR, Cabrera J, Griffiths AM, Hyams JS: Long-term Outcome of Children With Crohn's Disease: Results from a Large Multi-center North American Inception Cohort. Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

Lindsey G. Albenberg, Christel Chehoud, Colleen Judge, Christian Hoffman, Stephanie Grunberg, Kyle Bittinger, Robert N. Baldassano, James D. Lewis, Frederic D. Bushman, and Gary D. Wu: Gene Sequencing Reveals a Unique Fungal Signature in the Gut Microbiota of Pediatric Patients with Inflammatory Bowel Disease. Poster Presentation. Digestive Disease Week May 2014.

Lindsey Albenberg*, Tatiana Esipova*, Colleen Judge, Kyle Bittinger, Jun Chen, Stephanie Grunberg, Robert Baldassano, James D. Lewis, Hongzhe Li, Frederic D. Bushman, Sergei Vinogradov, Gary D. Wu: Radial Partitioning of the Gut Microbiota Associated with Tolerance to Oxygen and Assacharolytic Metabolism. Poster Presentation. Digestive Disease Week May 2014.

Kelsen JR, Moran CJ, Sasson A, Sarmady M, Gupta K, Pauly-Hubbard H, Rappaport E, Stolle C, Mamula P, Grossman AB, Piccoli D, Winter H, Baldassano R, Devoto M: Exome Sequencing Analysis of Candidate Genes in Very Early Onset IBD. Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

Jump C, Sahn B, Wendel D, Muir AB, Fish S, Augustine M, Ballantine A, Lin HC, Albenberg L: Teaching Residents GI in a "Flipped Classroom" on an Inpatient Pediatric Gastroenterology Rotation. Poster Presentation. Digestive Disease Week May 2014.

Grossi V, Lerer T, Leleiko NS, Mack DR, Griffiths AM, Otley AR, Pfefferkorn MD, Rosh JR, Oliva-Hemker M, Saeed SA, Grossman AB, Keljo D, Sudel1 B, Kappelman M, Faubion WA, Schaefer M, Tomer G, Deslandres C, Cabrera1 J, Carvalho R, Hitch M, Morganstern J, Kay MH, Rick J, Markowitz J, Hyams JS: Durability of Maintenance Infliximab Therapy in Children with Crohn's Disease: Are gender and concomitant immunomodulators more important than we thought? Digestive Disease Week, American Gastroenterological Association Annual Meeting, Chicago, IL May 2014.

2013

Cardinale CJ, Kelsen JR, Baldassano RN, & Hakonarson, H. (2013). Impact of exome sequencing in inflammatory bowel disease. World Journal of Gastroenterology: WJG, 19(40), 6721. Read abstract.

Cardinale CJ, Wei Z, Panossian S, Wang F, Kim CE, Mentch FD, Chiavacci RM, Kachelries KE, Pandey R, Grant SF, Baldassano RN, Hakonarson H. (2013). Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease. Genes and immunity. Read abstract.

Gupta K, Noble A, Kachelries KE, Albenberg L, Kelsen JR, Grossman AB, Baldassano RN. (2013). A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflammatory Bowel Diseases. [In process] Read abstract.

Tsampalieros A, Lam CK, Spencer JC, Thayu M, Shults J, Zemel BS, Herskovitz RM, Baldassano RN, Leonard MB. (2013). Long term inflammation and glucocorticoid therapy impair skeletal modeling during growth in childhood Crohn's disease. Journal of Clinical Endocrinology & Metabolism. Read abstract.

Walters TD, Kim M, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, Leleiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS. (2013). Comparative effectiveness of early therapy with anti-tumor necrosis factor-α vs. an immunomodulator in children With Crohn’s disease. Gastroenterology. Read abstract.

Wei Z, Wang W, Bradfield J, Li J, Cardinale C, Frackelton E, Kim C, Mentch F, Van Steen K, Visscher PM, Baldassano RN, Hakonarson H (2013). Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease. The American Journal of Human Genetics. Read abstract.

Zeisler B, Lerer T, Markowitz J, Mack D, Griffiths A, Bousvaros A, ... & Hyams J. (2013). Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis. Journal of Pediatric Gastroenterology and Nutrition, 56(1), 12-18. Read abstract

2012

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2012). Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. Journal of Pediatric Psychology, 37(3), 282-291. Read abstract.

Guilfoyle SM, Denson LA, Baldassano RN, & Hommel KA. (2012). Paediatric parenting stress in inflammatory bowel disease: application of the Pediatric Inventory for Parents. Child: Care, Health and Development, 38(2), 273-279. Read abstract.

Hyams JS, Griffiths A, Markowitz J, Baldassano RN, Faubion WA Jr, Colletti RB, Dubinsky M, Kierkus J, Rosh J, Wang Y, Huang B, Bittle B, Marshall M, Lazar A. (2012). Safety and efficacy of adalimumab for moderate to severe Crohn's disease in children. Gastroenterology, 143(2), 365-374. Read abstract.

Hyams J, Damaraju L, Blank M, Johanns J, Guzzo C, Winter HS, Kugathasan S, Cohen S, Markowitz J, Escher JC, Veereman-Wauters G, Crandall W, Baldassano R, Griffiths A2012). Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis. Clinical Gastroenterology and Hepatology, 10(4), 391-399. Read abstract.

Kelsen, JR, & Wu, GD. (2012). The gut microbiota, environment and diseases of modern society. Gut Microbes, 3(4), 374-382. Read abstract.

Otley A, LeLeiko N, Langton C, Lerer T, Mack D, Evans J, ... & Hyams J. (2012). Budesonide use in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 55(2), 200-204. Read abstract.

Prosnitz AR, Leonard MB, Shults J, Zemel BS, Hollis BW, Denson LA, Baldassano RN, Cohen AB, Thayu M. (2012). Changes in vitamin D and parathyroid hormone metabolism in incident pediatric Crohn's disease. Inflammatory Bowel Diseases. Read abstract.

Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI.. (2012). Human gut microbiome viewed across age and geography. Nature, 486(7402), 222-227. Read abstract.

2011

Albenberg LG, Lewis JD, & Wu GD. (2012). Food and the gut microbiota in inflammatory bowel diseases: a critical connection. Current Opinion in Gastroenterology, 28(4), 314-320. Read abstract.

Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, ... Baldassano RN,… & Mowat C. (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics, 43(3), 246-252. Read abstract.

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2011). Disease activity, behavioral dysfunction, and health‐related quality of life in adolescents with inflammatory bowel disease. Inflammatory Bowel Diseases,17(7), 1581-1586. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(1), 95. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Patient and parent psychosocial factors associated with health-related quality of life in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition, 52(3), 295. Read abstract.

Hommel KA, Denson LA, & Baldassano RN. (2011). Oral medication adherence and disease severity in pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(3), 250. Read abstract.

Hommel KA, Odell S, Sander E, Baldassano RN, & Barg FK. (2011). Treatment adherence in paediatric inflammatory bowel disease: perceptions from adolescent patients and their families. Health & Social Care in the Community, 19(1), 80-88. Read abstract.

Hyams JS, Lerer T, Mack D, Bousvaros A, Griffiths A, Rosh J, … Grossman A,  ... & Markowitz J. (2011). Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. The American Journal of Gastroenterology, 106(5), 981-987. Read abstract.

Hyams J, Walters TD, Crandall W, Kugathasan S, Griffiths A, Blank M, ... & Baldassano R. (2011). Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn's disease in children: REACH open-label extension. Current Medical Research & Opinion, 27(3), 651-662. Read abstract.

Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, ... & Baldassano RN. (2011). Recurrence rate of Clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflammatory Bowel Diseases, 17(1), 50-55. Read abstract.

Odell S, Sander E, Denson LA, Baldassano RN, & Hommel KA. (2011). The contributions of child behavioral functioning and parent distress to family functioning in pediatric inflammatory bowel disease. Journal of Clinical Psychology in Medical Settings, 18(1), 39-45. Read abstract.

Turner D, Travis SP, Griffiths AM, Ruemmele FM, Levine A, Benchimol EI, ... Baldassano RN,…& Russell RK. (2011). Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN. The American Journal of Gastroenterology, 106(4), 574-588. Read abstract.

Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA, Bewtra M, Knights D, Walters WA, Knight R, Sinha R, Gilroy E, Gupta K, Baldassano R, Nessel L, Li H, Bushman FD, Lewis JD. (2011). Linking long-term dietary patterns with gut microbial enterotypes. Science, 334(6052), 105-108. Read abstract.

Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, & Friedman JR. (2011). Circulating microRNA is a biomarker of pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 53(1), 26-33. Read abstract.

2010

Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, ... Baldassano RN,… & Van Gossum A. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature genetics, 42(12), 1118-1125. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, Winter HS, Baldassano RN, Abramson O, Smith T, Heyman MB. (2010). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 16(4), 638-644. Read abstract.

Hommel KA, & Baldassano RN. (2010). Brief report: Barriers to treatment adherence in pediatric inflammatory bowel disease. Journal of Pediatric Psychology, 35(9), 1005-1010. Read abstract.

Hyams JS, Lerer T, Griffiths A, Pfefferkorn M, Stephens M, Evans J, … Grossman A ... & Markowitz J. (2010). Outcome following infliximab therapy in children with ulcerative colitis. The American Journal of Gastroenterology. Read abstract.

Ingerski LM, Baldassano RN, Denson LA, & Hommel KA. (2010). Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 35(6), 683-691. Read abstract.

Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, ... & Baldassano RN. (2010). Phase I trial of sargramostim in pediatric Crohn's disease. Inflammatory Bowel Diseases, 16(7), 1203-1208. Read abstract.

Mascarenhas MR, & Thayu M. (2010). Pediatric inflammatory bowel disease and bone health. Nutrition in Clinical Practice, 25(4), 347-352. Read abstract.

Thayu M, Denson LA, Shults J, Zemel BS, Burnham JM, Baldassano RN, ... & Leonard MB. (2010). Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology, 139(2), 430-438. Read abstract.

Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, ... & Hakonarson, H. (2010). Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics, 19(10), 2059-2067. Read abstract.

2009

Ingerski LM, Baldassano RN, Denson LA, Hommel KA. (2009) Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 1-9. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, et al. (2009). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 2009 Sept. 6 (Epub ahead of print)  Read abstract.

Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, (2009). Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics, 84, 399 -405. Read abstract.

Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, et al. (2009). Variation in care in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 49(3), 297–303. Read abstract.

Crandall W, Hyams J, Kugathasan S, Griffiths A, Zrubek J, Olson A, et al. (2009). Infliximab therapy in children With concurrent perianal Crohn's disease: observations from REACH. Journal of Pediatric Gastroenterology and Nutrition, 49(2), 183–190. Read abstract.

Liu S, Russo PA, Baldassano RN, Sullivan KE. (2009). CD68 expression is markedly different in Crohn's disease and the colitis associated with chronic granulomatous disease. Inflammatory Bowel Disease, 15, 1213-1217. Read abstract.

Miele E, Pascarella F, Giannetti E, Quaglietta L, Baldassano RN, Staiano A. (2009) Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitis. American Journal of Gastroenterology, 104:437–443. Read abstract.

Heyman MB, Garnett EA, Shaikh N, Huen K, Jose FA, Harmatz P, Winter HS, et al. (2009) Folate concentrations in pediatric patients with newly diagnosed inflammatory bowel disease. American Journal of Clinical Nutrition, 89, 545-550. Read abstract.

Dubner SE, Shults J, Baldassano RN, Zemel BS, Thayu M, Burnham JM, et al. (2009). Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease. Gastroenterology, 136, 123 -130. Read abstract.

Hommel KA, Davis CM, Baldassano RN. (2009). Objective versus subjective assessment of oral medication adherence in pediatric inflammatory bowel disease. Inflammatory Bowel Disease, 15, 589-59. Read abstract.

Jose FA, Garnett EA, Vittinghoff E, Ferry GD, Winter HS, Baldassano RN, et al. (2009). Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease. Inflammatory Bowel Disease, 15, 63-68. Read abstract.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Research Alliance for Pediatric IBD; International IBD Genetics Consortium, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H. (2009) Common variants at five new loci associated with early-onset inflammatory bowel disease. National Genetics, Nov 15. [Epub ahead of print] Read abstract.