Research: Bone Marrow Failure Diseases

CHOP's Pediatric & Adult Comprehensive Bone Marrow Failure Center launched in 2010, representing a major advance in bone marrow diseases. Bone marrow failure, which can be inherited or acquired, is the inability of the bone marrow to produce sufficient circulating blood cells. Monica Bessler, MD, PhD, is founder and director of the Center.

Molecular and genetic events that lead to bone marrow failure diseases

The goals of Dr. Bessler's research are to refine diagnostic tools and develop more effective and comprehensive treatments. Because blood cells play key roles in fighting infection, carrying oxygen, blood clotting and other important biological processes, better understanding of their production and functions may have medical implications beyond blood disorders. 

Next Steps