Soma Jyonouchi, MD

Soma Jyonouchi, MD, is an attending physician in the Division of Allergy, Immunology Service, and Center for Cornelia de Lange Syndrome and Related Diagnoses at The Children's Hospital of Philadelphia.

Areas of Expertise: Immunodeficiency in Cornelia de Lange syndrome and other genetic syndromes
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Education and Training

    Medical School

    MD - Medical College of Wisconsin, Milwaukee, WI


    Pediatrics - Children's Hospital and Research Center at Oakland, Oakland, CA


    Allergy and Immunology - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Allergy and Immunology

  • Titles and Academic Titles

    Attending Physician

    Instructor in Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Publications



    Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinkoski H, Nadeau K, et al. Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1. J Allergy Clin Immunol. Epub 2011 Sep 28. Cited in PubMed; PMID 21962774. Read the abstract

    Jyonouchi S, Abraham V, Orange JS, Spergel JM, Gober L, Dudek E, et al. Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin. J Allergy Clin Immunol. 2011 Jul;128(1):102-109.e13. Epub 2011 Apr 1. Cited in PubMed; PMID 21458849. Read the abstract

    Jyonouchi S, Forbes L, Ruchelli E, Sullivan KE. Dyskeratosis congenita: a combined immunodeficiency with broad clinical spectrum--a single-center pediatric experience. Pediatr Allergy Immunol. 2011 may;22(3):313-9. doi: 10.1111/j.1399-3038.2010.01136.x. Epub 2011 Feb 1. Cited in PubMed; PMID 21284747. Read the abstract


    Jyonouchi S, McDonald-McGinn DM, Bale S, Zackai EH, Sullivan KE. CHARGE (colomba, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness) syndrome and chromosome 22q11.2 deletion syndrome: a comparison of immunologic and nonimmunologic phenotypic features. Pediatrics. 2009 May;123(5):3871-7. Cited in PubMed; PMID 19403480. Read the article

    Jyonouchi S, Brown-Whitehorn TA, Spergel JM. Association of eosinophilic gastrointestinal disorders with other atopic disorders. Immunol Allergy Clin North Am. 2009 Feb;29(1):85-97, x. Cited in PubMed; PMID 19141344. Read the abstract

    Posters and Presentations


    Jyonouchi S. Primary immunodeficiency and genetics [presentation]. Arcadia University Genetic Counseling Masters Program; 2011 Apr 14; Glenside, PA.