Soma Jyonouchi, MD

Areas of Expertise: Immunodeficiency in Cornelia de Lange syndrome and other genetic syndromes
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Education and Training

    Medical School

    MD - Medical College of Wisconsin, Milwaukee, WI


    Pediatrics - Children's Hospital and Research Center at Oakland, Oakland, CA


    Allergy and Immunology - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Allergy and Immunology

  • Titles and Academic Titles

    Attending Physician

    Instructor in Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Publications



    Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinkoski H, Nadeau K, et al. Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1. J Allergy Clin Immunol. Epub 2011 Sep 28. Cited in PubMed; PMID 21962774. Read the abstract

    Jyonouchi S, Abraham V, Orange JS, Spergel JM, Gober L, Dudek E, et al. Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin. J Allergy Clin Immunol. 2011 Jul;128(1):102-109.e13. Epub 2011 Apr 1. Cited in PubMed; PMID 21458849. Read the abstract

    Jyonouchi S, Forbes L, Ruchelli E, Sullivan KE. Dyskeratosis congenita: a combined immunodeficiency with broad clinical spectrum--a single-center pediatric experience. Pediatr Allergy Immunol. 2011 may;22(3):313-9. doi: 10.1111/j.1399-3038.2010.01136.x. Epub 2011 Feb 1. Cited in PubMed; PMID 21284747. Read the abstract


    Jyonouchi S, McDonald-McGinn DM, Bale S, Zackai EH, Sullivan KE. CHARGE (colomba, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness) syndrome and chromosome 22q11.2 deletion syndrome: a comparison of immunologic and nonimmunologic phenotypic features. Pediatrics. 2009 May;123(5):3871-7. Cited in PubMed; PMID 19403480. Read the article

    Jyonouchi S, Brown-Whitehorn TA, Spergel JM. Association of eosinophilic gastrointestinal disorders with other atopic disorders. Immunol Allergy Clin North Am. 2009 Feb;29(1):85-97, x. Cited in PubMed; PMID 19141344. Read the abstract

    Posters and Presentations


    Jyonouchi S. Primary immunodeficiency and genetics [presentation]. Arcadia University Genetic Counseling Masters Program; 2011 Apr 14; Glenside, PA.