Jessica W. Wen, MD

Papers

2022

Ritter AL, Gold J, Hayashi H, Ackermann AM, Hanke S, Skraban C, Cuddapah S, Bhoj E, Li D, Kuroda Y, Wen J, Takeda R, Bibb A, El Chehadeh S, Piton A, Ohl J, Kukolich MK, Nagasaki K, Kato K, Ogi T, Bhatti T, Russo P, Krock B, Murrell JR, Sullivan JA, Shashi V, Stong N, Hakonarson H, Sawano K, Torti E, Willaert R, Si Y, Wilcox WR, Wirgenes KV, Thomassen K, Carlotti K, Erwin A, Lazier J, Marquardt T, He M, Edmondson AC, Izumi K.: Expanding the Phenotypic Spectrum of ARCN1-related syndrome. Genet Med 24(6): 1227-1237, Jun 2022.

2021

Clarkston, K., Lee, J., Donoghue, S., Peters, H., Eiroa, H., Shah, A.A.,  Loomes, K., Wen, J., Oliver, M., Hardikar, W., Prada, C.E., Asai, A.: Acute liver dysfunction with delayed peak of serum aminotransferase levels as a presentation of ornithine transcarbamylase deficiency in females. AM J Med Genet 185(3): 909-915, 3 2021.

Hartung, E.A., Calle-Toro, J.S., Lopera, C.M., Wen, J., Carson, R.H.,  Dutt, M., Howarth, K., Furth, S.L., Darge, K., Serai, S.D. : Magnetic resonance elastography to quantify liver disease severity in autosomal recessive polycystic kidney disease. Abdom Radiol  46(2): 570-580, 2 2021.

Jonas, M.M., Rhee, S., Kelly, D.A., Del Valle-Segarra, A., Feiterna-Sperling, C., Gilmour, S., Gonzalez-Peralta, R.P., Hierro, L., Leung, D.H., Ling, S.C., Lobzin, Y., Lobritto, S., Mizuochi, T., Narkewicz, M.R., Sabharwal, V., Wen, J., Lon, H.K., Marcinak, J., Topp, A., Tripathi, R., Sokal, E.: Pharmacokinetics, safety, and efficacy of glecaprevir/pibrentasvir in children with chronic hepatitis C virus: part 2 of the DORA study Hepatology 74(1): 19-27, 7 2021.

2020

Mody, S., Rosenthal,P.,Narkewicz, M.R., Yao, B.B., Jolley, C.D., Lobritto, S.J., Wen, J., Molleston, J.P., Hsu, E.K., Jonas, M.M., Zha, J., Liu, L., and Leung, D.H. : Ombitasvir, Paritaprevir, Ritonavir and Dasabuvir Mini-tabs +/- Ribavirin for Children Aged 3-11 Years With Hepatitis C.  Adv Ther. 37(7): 3299-3310, July 2020.

2019

Hartung EA, Wen J, Poznick L, Furth SL, Darge K.: Ultrasound Elastography to Quantify Liver Disease Severity inAutosomal Recessive Polycystic Kidney Disease.  J Pediatr  209: 107-115, June 2019.

2018

Murray, K.F., Balistreri, W. F., Bansal, S., Whitworth, S.,  Evans, H.M., Gonzalez-Peralta, R.P., Wen, J., Massetto, B., Kersey, K., Shao, J.,  Garrison, K.L., Parhy, B., Brainard, D.M., Arnon, R., Gillis, L., Jonas, M.M., Lin, C.H., Narkewicz, M.R., Schwarz, K., Rosenthal, P.: Safety and Efficacy of Ledipasvir-Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6-11. Hepatology Aug 2018.

2016

Balistreri1 WF, Murray KF, Rosenthal P, Bansal S, Lin HC, Kersey K, Massetto B, Zhu Y, Kanwar B, German P, Svarovskaia E, Brainard DM, Wen J, Gonzalez-Peralta RP, Jonas MM, and Schwarz K: The safety and effectiveness of Ledipasvir-Sofosbuvir in adolescents 12 to 17 Years old with hepatitis C virus genotype 1 infection. Hepatology. 2016 Dec 20. doi: 10.1002/hep.28995. [Epub ahead of print]

Muir A, Otero H, Blinman T, Wen J: Use of MRI with hepatobiliary specific contrast agent for precise localization of bile duct leak. J Pediatr Gastroenterol Nutr 63(3): e36, September 2016 Notes: DOI: 10.1097/MPG.0000000000000531 

Schwarz K. Molleston JP, Jonas MM, Wen J, Murray K, Rosenthal P, Gonzalez-Peralta RP, Lobritto SJ, Mogul D, Hooper G, Warne C, Thompson B: Durability of response in children treated with pegylated interferon alfa-2a +/- ribavirin for chronic hepatitis C. J Pediatr Gastroenterol Nutr 62(1): 93-6, Jan 2016.

2015

Stoddard MB, Li H, Wang S, Saeed M, Andrus L, Ding W, Jiang X, Learn GH, von Schaewen M, Wen J, Goepfert PA, Hahn BH, Ploss A, Rice CM, Shaw GM.: Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4. MBio.  6(2): e02518-14, Febuary 2015.

2014

Jonas MM, Schwarz KB, Gonzalez-Peralta R, Lobritto S, Molleston JP, Murray KF, Rosenthal P, Wen J, Wat C, Pavlovic V, Warne C: Long-term growth outcomes in children treated for chronic hepatitis C J Pediatr 165(6): 1252-4, December 2014.

Wen JW, Furth SL, Ruebner RL: Kidney and liver transplantation in children with fibrocystic liver-kidney disease: Data from the US Scientific Registry of Transplant Recipients: 1990-2010. Pediatric Transplantation 18(7): 726-32, November 2014.

2012

Wen Jessica, Friedman Joshua R: miR-122 regulates hepatic lipid metabolism and tumor suppression. The Journal of clinical investigation 122(8): 2773-6, Aug 2012. PMCID: PMC3408753.

2011

Wen, J.: Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease. Clinical and Translational Science 4(6): 460-465, December 2011.

Books

2014

Ruchelli, E.D., Wen, J.W., Rand, E.B. : Hepatitis and Liver Failure in Infancy and Childhood. Pathology of Pediatric Gastrointestinal and Liver Disease. Russo, P., Ruchelli, E., Piccoli, D. (eds.). March 2014.

Chapters

2022

Ruchelli, E.D., Wen, J.W.: Hepatitis and Liver Failure in Infancy and Childhood. Pathology of Pediatric Gastrointestinal and Liver Disease.  Russo, P., Ruchelli, E., Piccoli, D. (eds.). 2022 Notes: In press.

Wen J, Liacouras C: Chapters on peritonitis and chylous ascites. Nelson Textbook of Pediatrics, 21st Ed 2022 Notes: In press.

2015

Wen J, Liacouras C: Chapters on peritonitis and chylous ascites   Nelson Textbook of Pediatrics, 20th Ed  Kliegman RM (eds.). Elsevier, May 2015.

2014

Ruchelli E, Wen J, Rand E : Hepatitis and liver failure in infancy and childhood. Pathology of Pediatric Gastrointestinal and Liver Disease, 2nd Edition. Russo P, Ruchelli E, Piccoli D (eds.). Springer, June 2014.

2012

Wen, J. & Fernando del Rosairo, J.: Chapter on Congenital Hepatic Fibrosis. 5 Minute Pediatric Consult, 6th ed. M. William Schwartz (eds.). Lippincott Williams & Wilkins, Page: 214-215, 2012.

2011

Wen, J. & Liacouras, C: Chapters on Peritonitis and Chylous Ascites. Nelson Textbook of Pediatrics, 19th Ed. Kliegman, R.M. et al. (eds.). Elsevier, Page: 1416-1418, 2011.

Wen, J. & Graham R.: Chapter on Inflammatory Bowel Disease. Netter's Pediatrics Florin, T. & Ludwig, S. (eds.). Elsevier, Page: 698-703, June 2011.

Wen, J. & Piccoli, D.: Biliary Tree- Normal Anatomy, Development, Physiology, and Microanatomy The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. Sondheimer, J. & Waasdorp Hurtado, C. (eds.). Castle Connolly Graduate Medical Publishing, Ltd, Page: 207-208, 2011.

Posters and Presentations

2023

Leung DH, Whitworth S, Wen J et al.: Long-Term Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antivirals in Pediatric Patients With Hepatitis C Virus. AASLD: The Liver Meeting 2023 2023.

2022

Wen, J., Whitworth, S., Leung, D.H., Rosenthal, P., Lin, C.H., Karnsaku, W., Bansal, S., Arnon, R., Romero, R., Rao, G.S., Narkewicz, M.R., Honegger, J.R., Jolly, C., Jonas, M.M., Shao, J., Brainard, D.M., Kersey, K., Gaggar, A., Balistreri, W.F., Hardikar, W., Gonzalez-Peralta, R.P.: Long term follow-up of safety and efficacy of sofosbuvir-based treatments for chronic HCV infection in pediatric patients. 54th Annual Meeting of ESPGHAN  June 2022.

2021

Mizuochi, T., Jonas, M.M., Rhee, S., Kelly, D.A., Del Valle-Segarra, A., Feiterna-Sperling, C., Gilmour, S., Gonzalez-Peralta, R., Hierro, L., Leung, D.H., Ling, S.C., Lobzin, Y., Lobritto, S., Narkewicz, M.R., Sabharwal, V., Wen, J., Lon, H.K., Marcinak, J., Topp, A., Tripathi, R., Sokal, E.: Safety and efficacy of glecaprevir/pibrentasvir in pediatric patients with genotypes 1-6 chronic hepatitis C virus (HCV) infection: part 2 of the DORA study. Japan Society of Hepatology - 57th Annual Meeting June 2021.

Wen, J., Whitworth, S., Leung, D., Rosenthal, P., Lin, C.H., Karnsakul, W., Bansal, S., Arnon, R., Romero,R., Rao, G.S., Narkewicz, M.R., Honegger, J.R., Jolly, C., Jonas, M., Shao, J., Gaggar, A., Kersey, K., Balistreri, W.F., Hardikar, W., Gonzalez-Peralta, R.P.: Long term follow-up of safety and efficacy of sofosbuvir-based HCV DAAs in pediatric patients   Asian Pacific Association for the Study of the Liver (APASL) Annual Meeting 2021.

 

Invited Lectures

2022

Wen, J. "Chronic viral hepatitis in children." The Children's Hospital of Philadelphia Division of Infectious Disease Journal Club. Dec 2022.