Jessica W. Wen, MD

Jessica W. Wen, MD, is director of the Viral Hepatitis Treatment Program and a board certified pediatric gastroenterologist at The Children's Hospital of Philadelphia. She also works with CHOP's Liver Transplant Program and the Biesecker Pediatric Liver Center.

Locations: Main Campus
Phone: 215-590-3630

  • Education and Training

    Medical School

    MD - Baylor College of Medicine, Houston, TX


    Pediatrics - Texas Children's Hospital/Ben Taub General Hospital, Houston, TX


    Pediatric Gastroenterology - The Children's Hospital of Philadelphia, Philadelphia, PA (Chief GI fellow, 2009-10)

    Board Certification

    Pediatric Gastroenterology

    Undergraduate Degree

    BS in Biology - Massachusetts Institute of Technology, Cambridge, MA

    Graduate Degree

    MSc in Translational Research - University of Pennsylvania, Philadelphia, PA

  • Titles and Academic Titles

    Director, Viral Hepatitis Treatment Program

    Attending Physician

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Research Interests

    Hepatitis B and hepatitis C
    Liver fibrosis
    Congenital hepatic fibrosis/autosomal recessive polycystic kidney disease

  • Publications




    Wen, J. & Liacouras, C.: Chapters on Peritonitis and Chylous Ascites Nelson Textbook of Pediatrics, 20th Ed Kliegman, R.M. et al. (eds.). Elsevier, May 2013.


    Wen, J. & Fernando del Rosairo, J.: Chapter on Congenital Hepatic Fibrosis. 5 Minute Pediatric Consult, 6th ed. M. William Schwartz (eds.). Lippincott Williams & Wilkins, Page: 214-215, 2012.


    Wen, J. & Liacouras, C: Chapters on Peritonitis and Chylous Ascites. Nelson Textbook of Pediatrics, 19th Ed. Kliegman, R.M. et al. (eds.). Elsevier, Page: 1416-1418, 2011.

    Wen, J. & Graham R.: Chapter on Inflammatory Bowel Disease. Netter's Pediatrics Florin, T. & Ludwig, S. (eds.). Elsevier, Page: 698-703, June 2011.

    Wen, J. & Piccoli, D.: Biliary Tree- Normal Anatomy, Development, Physiology, and Microanatomy The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. Sondheimer, J. & Waasdorp Hurtado, C. (eds.). Castle Connolly Graduate Medical Publishing, Ltd, Page: 207-208, 2011.



    Malik S, Arva N, Wen J: Liver transplantation in a pediatric patient with multi-focal HCC and HCV. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2012 Annual Meeting 2012.

    Wen J, Ruebner R, Kaplan B, Furth S: The natural history of fibrocystic liver disease in pediatric organ transplant recipients North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) 2012 Annual Meeting 2012.



    Wen,J. & Haber, B.: Maternal-fetal transmission of HCV- What's so special about babies? Journal of Pediatric Gastroenterology and Nutrition. Lippincott Williams & Wilkins, June 2013 Notes: Accepted


    Wen Jessica, Friedman Joshua R: miR-122 regulates hepatic lipid metabolism and tumor suppression. The Journal of clinical investigation 122(8): 2773-6, Aug 2012. PMCID: PMC3408753.


    Wen, J.: Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease. Clinical and Translational Science 4(6): 460-465, December 2011.

  • Awards and Honors

    2013, Fellows Faculty Honor Roll
    2012-2014, University of Pennsylvania Master of Translational Research Fellowship
    2012, Young Faculty Clinical Investigator Award/ North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
    2011, American Association for the Study of Liver Disease(AASLD)/American Liver Foundation(ALF) Liver Scholar Award
    2011, Studies of Pediatric Liver Transplantation (SPLIT) Annual Meeting Young Faculty Travel Award
    2010, North American Society for Pediatric Gastroenterology, Hepatology & Nutrition (NASPGHAN) Annual Meeting 2010 Poster of Distinction
    2010, AASLD Annual Meeting Young Investigator Travel Award
    2009-2011, NIH NRSA F32 Individual Research Training Fellowship
    2009-2010, Chief Fellow, The Children's Hospital Pediatric GI Fellowship Program
    2008-2012, NIH Loan Repayment Program
    2008-2009, NIH NRSA T32 Institution Training Fellowship
    1999-2000, MIT Undergraduate Research Opportunities Program Direct Research Funding with Howard Hughes Medical Institute

  • Editorial and Academic Positions

    Editorial positions

    2012-present, Hepatology peer-reviewer
    2012-present, World Journal of Pediatrics peer-reviewer

    Academic and institutional committees

    2013, Consultant reviewer, The Children's Hospital of Philadelphia Institutional Review Board
    2013-2016, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) Hepatology Committee
    2009-present, Member, The Children's Hospital of Philadelphia GI Division Quality and Safety Committee

  • Leaderships

    Memberships in professional organizations

    American Academy of Pediatrics
    American Association For The Study of Liver Disease (AASLD)
    American Gastroenterological Association (AGA)