Eosinophilic (e-o-sin-o-fil-ik) esophagitis (e-so-fa-gi-tis), referred to as EoE, is an chronic allergic inflammatory disease of the esophagus, the muscular tube that carries food from the throat to the stomach. In the past, it has been referred to as EE.
During an allergic reaction, various cells congregate and cause symptoms like redness, swelling and itchiness. A white blood cell called an eosinophil is one of the types of cells behind an allergic reaction.
Eosinophils are an important part of the immune system and there are always small quantities in the blood and intestine fighting parasites and performing other duties. However, eosinophils cause problems when they appear in high quantities in areas other than the blood and intestine.
EoE was unknown 30 years ago but, today, diagnoses of this disorder are increasing rapidly.
The Center for Pediatric Eosinophilic Disorders at The Children's Hospital of Philadelphia treats children with eosinophilic esophagitis and other eosinophilic disorders, such as eosinophilic gastroenteritis.
Currently we treat 1,500 infants, children and teenagers with EoE — the largest clinical population in the world. Our patients come from all over the world.
For more information about how the CHOP can help your child, please visit these links:
If you would like more information about eosinophilic disorders or would like to arrange a consult, please contact Michele Shuker, our clinic coordinator, at 267-426-7003 or by email.