Neonatal Craniofacial Program

Neonatal Craniofacial Research

Research is integral to the Neonatal Craniofacial Program, as we work to develop a broad, evidence-based approach to the diagnosis, treatment and management of craniofacial disorders. A prerequisite for this is accurate and meaningful data.

Below is a list of some of the cutting-edge clinical and basic science research studies our team is currently involved in.  

Clinical outcomes research

Computer-aided surgery (CAD/CAM)

Distraction osteogenesis

Craniofacial biology in syndromic synostosis

Basic science research


Obstructive sleep apnea in infants with cleft palate and tongue-based airway obstruction

This prospective cohort study seeks to better understand the impact of craniofacial abnormalities on upper airway obstruction in infants.

The study’s goal is to identify the prevalence of obstructive sleep apnea syndrome (OSAS) in infants with either isolated cleft palate or tongue-based obstruction due to micrognathia or retrognathia, and evaluate the contribution of airway size to OSAS and the impact of OSAS on infant development in children with these conditions.

Participation in this observational study includes obtaining a 16-channel overnight polysomnogram (sleep study), a lateral neck radiograph at the time of enrollment and at a six-month follow-up visit, and an outpatient neurodevelopmental assessment.

Reviewed by: Scott Bartlett, MD, and Janet Lioy, MD, FAAP
March 2013

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