Orthopedic Surgery

Ewing Sarcoma

What is Ewing sarcoma?
Ewing sarcoma is a family of bone tumors that includes:


Ewing sarcoma most frequently occurs in teenagers, and more often is found in males than females. The legs are most commonly affected, and pain and swelling are common symptoms.

When Ewing sarcoma is found, our musculoskeletal tumor team provides the expertise to improve your child's chance for recovery (prognosis). Diagnostic tests including tissue biopsies, X-rays, magnetic resonance imaging (MRI) scans, and computed tomography (CT) scans will be done.

Treatment will depend on factors including the size and location of the tumor, how far it has spread, and the age, size, development, and general health of the patient.


Staging the tumor
When Ewing sarcoma is present, more tests will be done to find out if the cancer cells have spread to other parts of the child's body. Called staging, this helps us plan the best treatment options for your child.

Ewing sarcoma is usually categorized into the following stages:


How we can help — treatment options
Surgery is the common treatment for Ewing sarcoma. Working in our state-of-the-art operating suite, our expert surgeons will remove as much of the cancer as possible.

Another treatment option is radiation therapy. This uses high-energy rays to kill cancer cells and shrink tumors.

Chemotherapy uses drugs to kill cancer cells. The drugs enter the child's bloodstream and travel through the body to kill cancer cells. Chemotherapy may be taken by mouth or put into the body through a needle in a vein or muscle.

An additional treatment is called myeloablative therapy with stem cell support. This is an intense regimen of chemotherapy designed to destroy all rapidly dividing cells such as those found in Ewing sarcoma. Unfortunately, this also destroys needed blood cells. However, this situation can be improved by increasing the number of stem cells. A stem cell is a cell whose so-called daughter cells are able to create other types of blood cells. When the number of stem cells is increased, they replace the cells that were destroyed when high doses of chemotherapy were used to kill remaining tumor cells.


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