William H. Peranteau, MD

William Peranteau, MD is an attending pediatric and fetal surgeon at The Children’s Hospital of Philadelphia.

Locations: Main Campus
Phone: 215-590-2730

  • Background

    Dr. William Hughes Peranteau is an attending surgeon in the Division of Pediatric General, Thoracic and Fetal Surgery at The Children’s Hospital of Philadelphia and an assistant professor of surgery at the Perelman School of Medicine at the University of Pennsylvania.

    His areas of interest include fetal biology, fetal and neonatal surgery, and general pediatric surgery. A native of Gloucester City, New Jersey, just 10 miles east of CHOP’s Main campus, Dr. Peranteau earned his bachelor’s degree in molecular biology from Princeton University, and his medical degree from the University of Pennsylvania.

    “CHOP is unique in that it integrates cutting-edge basic science research with the largest fetal care center in the world, offering a multidisciplinary team of experts that have advanced the field and will continue to advance the field into the future,” he says. “I’m very lucky to have grown up in this area, and now, to be able to practice pediatric surgery at the best possible place and be involved in such an exciting research community here is awesome.”

    Prior to joining the Center team in 2012, Dr. Peranteau completed his residency in general surgery at Brigham and Women’s Hospital, Boston, Mass., and a fellowship in pediatric general surgery at CHOP. He also served as a research fellow with CHOP’s Center for Fetal Research for four years, investigating the role of in utero bone marrow and stem cell transplantation for the management of congenital hematologic disorders such as sickle cell disease.

    “This area of research is potentially readily translatable to clinical application,” Dr. Peranteau says. “The group of people not only within the Department of Pediatric General Surgery and the Center for Fetal Diagnosis and Treatment but also the CHOP community as a whole, with experts in every field of pediatrics, make CHOP an unbelievable place to work and a place that’s ripe for advancing clinical medicine.”

    Dr. Peranteau has published articles in the Journal of the American College of Surgeons, the Journal of Pediatric Surgery, Fetal Diagnosis and Therapy, Experimental Hematology and Blood. He is board certified in general surgery.

    To contact the Center for Fetal Diagnosis and Treatment, call 1-800-468-8376 (1-800-IN-UTERO).

  • Education and Training

    Medical School

    MD — University of Pennsylvania School of Medicine, Philadelphia, PA


    General Surgery — Brigham and Women's Hospital, Boston, MA


    General Surgery — Brigham and Women's Hospital, Boston, MA


    Research — The Children's Hospital of Philadelphia, Philadelphia, PA
    Pediatric Surgery — The Children's Hospital of Philadelphia, Philadelphia, PA

  • Titles and Academic Titles

    Attending Surgeon

  • Conditions Treated
  • Departments and Services
  • Publications



    Karlawish JHT, Peranteau WH. Genetic screening in general internal medicine. In: Mahowald MB, Sheuerle A, Aspinwall T, editors. Genetics in the clinic: clinical, ethical, and social implications for primary care. St Louis (MO): Mosby; 2001. p. 181-87.



    Laje P, Hedrick HL, Flake AW, Adzick NS, Peranteau WH. Delayed abdominal closure after congenital diaphragmatic hernia repair. J Pediatr Surg. 2015 Nov 11. Read the abstract.

    Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2015 Oct 23. Read the abstract.

    Partridge EA, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Frequency and complications of inguinal hernia repair in giant omphalocele. J Pediatr Surg. 2015 Oct. Read the abstract.

    Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016. Read the abstract.

    Laje P, Peranteau WH, Hedrick HL, Flake AW, Johnson MP, Moldenhauer JS, Adzick NS. Ex utero intrapartum treatment (EXIT) in the management of cervical lymphatic malformation. J Pediatr Surg. 2015 Feb;50(2):311-4. doi: 10.1016/j.jpedsurg.2014.11.024. Epub 2014 Nov 10.

    Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2. Read the abstract.

    Peranteau WH, Scott Adzick N, Boelig MM, Alan W F, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a single-institution review and predictors of survival in 75 cases. J Pediatr Surg. 2015 Feb;50(2):301-5. Read the abstract.

    Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6. Read the abstract.

    Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016. Read the abstract


    Endo M, Henriques-Coelho T, Zoltick PW, Stitelman DH, Peranteau WH, Radu A, et al. The developmental stage determines the distribution and duration of gene expression after early intraamniotic gene transfer using lentiviral vectors. Gene Ther. 2010 Jan;17(1):61-71. Epub 2009 Sep 3. Cited in PubMed; PMID 19727133. Read the abstract

    Peranteau WH, Havens JM, Harrington S, Gates JD. Reestablishing surgical care at Port au Prince General Hospital, Haiti. J Am Coll Surg. 2010 Jul;211(1):126-30. Epub 2010 May 26. Cited in PubMed; PMID 20610258. No abstract available.

    Posters and Presentations

    Peranteau W. Surgical management of insulinoma [presentation]. Annual Nursing Conference, The Children’s Hospital of Philadelphia; 2011 Nov; Philadelphia, PA.

    Peranteau W. Pediatric penetrating anorectal trauma [presentation]. Annual Day of Trauma sponsored by The Trauma Directors of the Philadelphia Area; 2010 Dec 4; The Union League, Philadelphia PA.

    Rogers S, Powers P, Peranteau WH, Havens J, Gates JD, Russell R, Riviello R, Dyer G. The BWH surgical response to Haiti [presentation].The Brigham and Women’s Hospital, Department of Surgery Grand Rounds; 2010 Mar; Boston, MA.

  • Editorial and Academic Positions

    Editorial positions

    Ad hoc reviewer, Digestive Diseases and Sciences