First Child to Receive Revolutionary CAR T Therapy Celebrates 10 Years Cancer Free
Published on
Emily Whitehead, now 17, received life-saving treatment at CHOP, transforming the field of cancer immunotherapy.
Cancer Immunotherapy Program News and Updates
11 - 20 of 55
CHOP Brings Together Experts to Discuss Precision Medicine in Pediatric Cancer Care
Published on
More than 250 experts gathered in Philadelphia and virtually to discuss the latest scientific advancements and breakthroughs in pediatric precision medicine oncology.
CHOP/Penn Study Shows CAR-T Cells Remain Active a Decade After Infusion
Published on
A new study in Nature has documented the longest persistence of CAR T cell therapy to date.
Aberrant Splicing of CD22 in Acute Lymphoblastic Leukemia Underlies Resistance to Immunotherapy
Published on
Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
Stephan Grupp, MD, PhD, a Panelist at Distinguished Conference About National Cancer Act
Published on
A cell and gene therapy expert, Grupp discussed progress in clinical care in the 50 years since the legislation was signed.
Positive Preliminary Data on CRISPR Treatment for Blood Diseases
Published on
A collaborative team of researchers, including Dr. Stephan Grupp, recently presented preliminary data showing that a CRISPR-based gene-editing therapy for inherited blood disorders is safe and effective.
CHOP Researchers Develop Humanized CAR T-Cell Therapy that Shows Potential for Patients with Relapsed B-ALL
Published on
The treatment modifies a domain in the CAR that targets CD19, making it look more human and therefore less likely to be rejected by patients.
CHOP Gene Therapy Experts Profiled in Philadelphia Magazine
Published on
CHOP researchers were interviewed as a part of a comprehensive article about cell and gene therapy in Philadelphia Magazine.
Shannon Maude, MD, Discusses Unique Challenges Facing CAR-T Cell Therapy in Healio Article
Published on
Dr. Shannon Maude, an attending physician in the Cancer Center at CHOP, provided expert insight on the unique challenges facing CAR T-cell therapy for pediatric indications in an article published in Healio’s February issue of Cell Therapy Next.
Children’s Doctor News and Updates: Winter 2020
Published on
Latest news including elections to NAM, cures for picky eaters, lawn mower injuries and more.