Clinical Chemistry, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
PhD - Cellular & Molecular biology, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Director of Clinical Chemistry
Assistant Professor of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania
Her research interests include biomarker development, test utilization and laboratory stewardship.
SoRelle JA, Patel K, Filkins L, Park JY. Mass Spectrometry for COVID-19. Clin Chem. 2020 Nov 1;66(11):1367-1368. doi: 10.1093/clinchem/hvaa222. PubMed PMID: 32956447; PubMed Central PMCID: PMC7543316.
Patel K. Commentary on A Curious Case of Primary Amenorrhea. Clin Chem. 2020 Sep 1;66(9):1154-1155. doi: 10.1093/clinchem/hvaa084. PubMed PMID: 32870991.
Vakili H, Umaña LA, Patel K. Isolated Orotic Aciduria in an 11-Year-Old Boy. Clin Chem. 2020 Feb 1;66(2):396-397. doi: 10.1093/clinchem/hvz012. PubMed PMID: 32040582.
Madhusudhan N, Hu B, Mishra P, Calva-Moreno JF, Patel K, Boriack R, Ready JM, Nijhawan D. Target Discovery of Selective Non-Small-Cell Lung Cancer Toxins Reveals Inhibitors of Mitochondrial Complex I. ACS Chem Biol. 2020 Jan 17;15(1):158-170. doi: 10.1021/acschembio.9b00734. Epub 2019 Dec 24. PubMed PMID: 31874028; PubMed Central PMCID: PMC7038911.
Phipps WS, Crossley E, Boriack R, Jones PM, Patel K. Quantitative amino acid analysis by liquid chromatography-tandem mass spectrometry using low cost derivatization and an automated liquid handler. JIMD Rep. 2020 Jan;51(1):62-69. doi: 10.1002/jmd2.12080. eCollection 2020 Jan. PubMed PMID: 32071840; PubMed Central PMCID: PMC7012744.
Phipps WS, Jones PM, Patel K. Amino and organic acid analysis: Essential tools in the diagnosis of inborn errors of metabolism. Adv Clin Chem. 2019;92:59-103. doi: 10.1016/bs.acc.2019.04.001. Epub 2019 Jun 8. Review. PubMed PMID: 31472756.
Patel K, Suh-Lailam BB. Implementation of point-of-care testing in a pediatric healthcare setting. Crit Rev Clin Lab Sci. 2019 Jun;56(4):239-246. doi: 10.1080/10408363.2019.1590306. Epub 2019 Apr 11. Review. PubMed PMID: 30973797.
Patel K, McElvania E. Diagnostic Challenges and Laboratory Considerations for Pediatric Sepsis. J Appl Lab Med. 2019 Jan;3(4):587-600. doi: 10.1373/jalm.2017.025908. Epub 2018 Nov 21. Review. PubMed PMID: 31639728.
SoRelle JA, Jiao R, Gao E, Veazey J, Frame I, Quinn AM, Day P, Pagels P, Gimpel N, Patel K. Impact of Hormone Therapy on Laboratory Values in Transgender Patients. Clin Chem. 2019 Jan;65(1):170-179. doi: 10.1373/clinchem.2018.292730. Epub 2018 Dec 5. PubMed PMID: 30518663.
Nguyen KQN, Jones PM, Patel K. A Newborn with Hypothermia and Hyperammonemia. Clin Chem. 2018 Feb;64(2):411-413. doi: 10.1373/clinchem.2017.278580. PubMed PMID: 29378745.
Patel KK, Qavi AJ, Hock KG, Gronowski AM. Establishing reference intervals for hCG in postmenopausal women. Clin Biochem. 2017 Mar;50(4-5):234-237. doi: 10.1016/j.clinbiochem.2016.11.017. Epub 2016 Nov 19. PubMed PMID: 27876610.
Patel KK, Gronowski AM. Heterophile antibody interference in qualitative urine/serum hCG devices: Case report. Clin Biochem. 2016 Jun;49(9):729-731. doi: 10.1016/j.clinbiochem.2015.12.018. Epub 2016 Mar 9. PubMed PMID: 26968106.
Szymanski JJ, Otrock ZK, Patel KK, Scott MG. Incidence of humoral hypercalcemia of malignancy among hypercalcemic patients with cancer. Clin Chim Acta. 2016 Jan 30;453:190-3. doi: 10.1016/j.cca.2015.12.017. Epub 2015 Dec 17. PubMed PMID: 26706788.
Dickinson JD, Alevy Y, Malvin NP, Patel KK, Gunsten SP, Holtzman MJ, Stappenbeck TS, Brody SL. IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy. 2016;12(2):397-409. doi: 10.1080/15548627.2015.1056967. Epub 2015 Jun 10. PubMed PMID: 26062017; PubMed Central PMCID: PMC4835964.
Patel KK, Scott MG. A Fatty blood sample. Clin Chem. 2015 Apr;61(4):672-3. doi: 10.1373/clinchem.2014.234831. PubMed PMID: 25818130.
Lassen KG, Kuballa P, Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L, Horn H, Mercer J, Yilmaz OH, Jaffe JD, Shamji AF, Bhan AK, Carr SA, Daly MJ, Virgin HW, Schreiber SL, Stappenbeck TS, Xavier RJ. Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7741-6. doi: 10.1073/pnas.1407001111. Epub 2014 May 12. PubMed PMID: 24821797; PubMed Central PMCID: PMC4040621.
Patel KK, Miyoshi H, Beatty WL, Head RD, Malvin NP, Cadwell K, Guan JL, Saitoh T, Akira S, Seglen PO, Dinauer MC, Virgin HW, Stappenbeck TS. Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. EMBO J. 2013 Dec 11;32(24):3130-44. doi: 10.1038/emboj.2013.233. Epub 2013 Nov 1. PubMed PMID: 24185898; PubMed Central PMCID: PMC3981139.
Patel KK, Stappenbeck TS. Autophagy and intestinal homeostasis. Annu Rev Physiol. 2013;75:241-62. doi: 10.1146/annurev-physiol-030212-183658. Epub 2012 Dec 3. Review. PubMed PMID: 23216414; PubMed Central PMCID: PMC3751401.
Cadwell K, Patel KK, Maloney NS, Liu TC, Ng AC, Storer CE, Head RD, Xavier R, Stappenbeck TS, Virgin HW. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell. 2010 Jun 25;141(7):1135-45. doi: 10.1016/j.cell.2010.05.009. PubMed PMID: 20602997; PubMed Central PMCID: PMC2908380.
Cadwell K, Patel KK, Komatsu M, Virgin HW 4th, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy. 2009 Feb;5(2):250-2. doi: 10.4161/auto.5.2.7560. Epub 2009 Feb 8. PubMed PMID: 19139628; PubMed Central PMCID: PMC2940227.
American Association of Clinical Chemistry
Academy of Clinical Laboratory Physicians and Scientists
Patient-centered Laboratory Utilization Guidance Services
Endocrine Society