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Antonella Cianferoni, MD, PhD

Attending Physician

Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania


Cianferoni A., Schroeder J.T., Vierucci A., Lichtenstein L.M., Georas S.N., Casolaro V. Differential Effects of Salicylates on IL-4 and IL-2 Expression in Human CD4+ T Lymphocytes. J Allergy Clin Immunol 1999;103 (2):922

Schroeder J.T., Cianferoni A., Lichtenstein L.M., Casolaro V. Enhanced secretion of IL-4 by human basophils following pre-treatment with Sodium Salicylate and Aspirin. J Allergy Clin Immunol 1999;103 (2):737

Valapour M., Cianferoni A., Cumberland J., Burke T., Seto E., Casolaro V., Georas S. Histone deacetylation inhibits Interlukin-4 (IL-4) gene expression. Am J Resp Crit Care Med, 1999;159

Cianferoni A., Schroeder JT, Clancy Keen J., Schmidt J.W., Georas S.N., Casolaro V. Dissociation of the effects of salicylates on IL-4 gene expression and NFAT activation in human T cell. J Allergy Clin Immunol 2000; 105 (p2):485

Florio G., Cianferoni A.,  Clancy Keen J., Schmidt J.W., Lakenan WA, Georas S.N., Casolaro V. NF-kB-dependent transcription of the IL-13 gene in activated T cells J Allergy Clin Immunol 2000;105 (p2):817

Novembre E., Cianferoni A., Lombardi E., Bernardini R., Favilli T., Pucci N., Brizzi I., Vierucci A. Significance of skin prick test reactivity and total serum IgE level in a group of children with atopic dermatitis seen at age 2 and at age 11. ERS

Keen J.C., Natarajan S. , Burke T., Guo J., Cianferoni A., Schmidt J., Casolaro V. Distinct signal requirements for IL-4 and IL-13 expression. cells J Allergy Clin Immunol J Allergy Clin Immunol 2001:107:489

Schroeder J.T., Miura K., Cianferoni A., Kim H.H., Roche E.M., Sin A.Z., Casolaro V. Nuclear Factor of Activated T Cell (NFAT) Expression in Human Basophils: Evidence for NFAT2 Involvement in IgE-mediated IL-4 Generation. J Allergy Clin Immunol 2001:107:1006

Cianferoni A., Novembre E., Lombardi E., Bernardini R., Mugnaini L., Pucci N., Vierucci A. Clinical features of severe acute anaphylaxis in patients admitted to an University Hospital: an 11 year retrospective review (1985-1996) J Allergy Clin Immunol 2001:107:197

Cianferoni A, Novembre E, Pucci N, Lombardi E, Bernardini R, Vierucci A. Clinical features of anaphylaxis in children: 7 years follow up of 46 cases. J Allergy Clin Immunol 2003:111:127

Cianferoni A, Ramesh N, GallegoMD, Geha RS. Wiskott-Aldrich protein (WASP) is important for NAFT and AP1 activation. J Allergy Clin Immunol 2004

Cianferoni A, Scott J, Bonilla FA, Dioun A, Gellis S, Geha R, Schneider L. Bilateral lower leg swelling and lymphocytic panniculitis in a patient with XLA. J Clinical Immunology  2005



1995 Best Medical Student Award in Florence University

1997 Extended Scholarship Award UCB Institute of Allergy

1998 International Fellowship UCB Institute of Allergy


Novembre E., Cianferoni A. Anafilassi (trans: Anaphylaxis). Chapter 20 in: “Emergenze pediatriche” (trans: Paediatric Critical Care) A. Sarti-P. Busoni Editor, Pacini ed.  Ospaedaletto (Pi), 1997: pp299-304

Novembre E., Cianferoni A., Vierucci A. L’immunoterapia specifica nel trattamento delle allergopatie respiratorie (trans: Specific immunotherapy in respiratory diseases treatment) 1998 Pisa:Chapter 3;pp353-358

Cianferoni A, Vierucci A La tosse nel bambino (trans. Cough in children) Chapter 13 in Allergologia Pediatrica- A. Vierucci   Selecta Medica ed. 2003

Vierucci A, Cianferoni A: La Tosse nel bambino (trans: Cough in children) 2005 Gentili ed, Pisa, Italy

Novembre E, Cianferoni A: Uricaria In children in press




Editorial and Academic Positions

  • Johns Hopkins University PhD student teaching in lab during their rotation/electives
  • Boston Children’s Hospital teaching to residents during their rotation in allergy and immunology
  • Boston Children’s Hospital PhD student teaching in lab during their rotation/electives



Original Papers

Poliak N, Elias M, Cianferoni A, Treat J. Acute generalized exanthematous pustulosis: the first pediatric case caused by a contrast agent. Ann Allergy Asthma Immunol. 2010 Sep;105(3):242-3. No abstract available.




Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr;42(4):289-91. Epub 2010 Mar 7. Read abstract.




Cianferoni A, Spergel JM. Food allergy: review, classification and diagnosis. Allergol Int. 2009 Dec;58(4):457-66. Epub 2009 Oct 25. Review. Read abstract.




Cianferoni A, Schneider L, Schantz PM, Brown D, Fox LM. Visceral larva migrans associated with earthworm ingestion: clinical evolution in an adolescent patient. Pediatrics. 2006 Feb;117(2):e336-9. Read abstract.

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