Joseph Rossano, MD, works in many roles as a pediatric cardiologist at The Children’s Hospital of Philadelphia. Dr. Rossano’s primary position is medical director of the Pediatric Heart Transplant and Heart Failure. He is also an attending physician in the Cardiac Center and the Cardiac Intensive Care Unit (CICU) and an assistant professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.
A graduate of the University of Arizona College of Medicine, Dr. Rossano won several awards for academic achievement during medical school. He completed his internship and residency at Seattle Children’s (formerly Children’s Hospital and Regional Medical Center), followed by three fellowships at Baylor College of Medicine and Texas Children’s Hospital. He was trained in pediatric cardiology, heart transplant, and advanced heart failure and cardiac intensive care.
Dr. Rossano came to The Children’s Hospital of Philadelphia in 2011 to help manage the Hospital’s busy heart failure, transplant and cardiac mechanical support programs, train residents and fellows, and conduct research on the epidemiology and outcomes of heart disease in children.
Dr. Rossano is principal investigator or co-investigator on several ongoing research studies. This research includes investigating the use of ventricular assist devices and artificial hearts in children, studying the effectiveness of post-transplant treatments for children who have received heart transplants, an observational study of children with heart failure, and building a registry of pediatric heart transplant patients that aims to further the knowledge of pediatric heart disease and transplantation.
Dr. Rossano has made dozens of presentations at meetings around the world and published manuscripts in journals such as The Journal of Heart and Lung Transplantation, the Journal of Cardiac Failure, Journal of Thoracic and Cardiovascular Surgery and Critical Care Medicine.
A frequent guest lecturer, Dr. Rossano has spoken at children’s hospitals and medical schools across the country on topics ranging from advances in cardiopulmonary resuscitation to postoperative care of patients with ventricular assist devices to heart failure in infants.
- Education and Training
MD - University of Arizona College of Medicine, Tucson, AZ
Pediatrics - University of Washington, Children's Hospital and Regional Medical Center, Seattle, WA
Pediatrics - University of Washington, Children's Hospital and Regional Medical Center, Seattle, WA
Pediatric Cardiology - Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Advanced Heart Failure/Cardiac Intensive Care - Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Heart Transplant - Baylor College of Medicine
General PediatricsPediatric Cardiology
MS in Clinical Research - Baylor College of Medicine, Houston, TX
- Titles and Academic Titles
Attending Cardiologist, Cardiac Center and the Cardiac Intensive Care Unit (CICU)
Medical Director, Pediatric Heart Transplant and Heart Failure
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
- Departments and Services
Rossano JW, Naim M, Nadkarni V, Berg RA. Epidemiology of pediatric cardiac arrest. In: da Cruz EM, Ivy DD, Hraska V, Jagger J eds. Pediatric Cardiology, Cardiac Surgery, and Intensive Care. New York, NY: Springer; 2013.
Naim M, Rossano JW, Nadkarni VM, Berg RA. Current CPR recommendations. In: da Cruz EM, Ivy DD, Hraska V, Jagger J eds. Pediatric Cardiology, Cardiac Surgery, and Intensive Care. New York, NY: Springer; 2012.
Rossano JW, Morales DLS, Fraser CD. Heart transplantation. In: Mavroudis C, Backer CL, editors. Pediatric Cardiac Surgery. 4th ed. Philadelphia, PA: Mosby; 2013.
Rossano JW, Price JF, Nelson DP. Treatment of heart failure in infants and children: medical management. In: Nichols DG, ed. Rogers’ Textbook of Pediatric Intensive Care. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008:1093-1110.
Kim JJ, Rossano JW, Nelson DP, Price JF, Dreyer WJ. Heart failure in infants and children: etiology, pathophysiology, and diagnosis of heart failure. In: Nichols DG, ed. Rogers’ Textbook of Pediatric Intensive Care. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008:1064-1074.
Rodriguez FH 3rd, Moodie DS, Parekh DR, Franklin WJ, Morales DL, Zafar F, et al. Outcomes of heart failure-related hospitalization with congenital heart disease in the United States. Congenit Heart Dis. Epub 2012 Nov 16. doi: 10.1111/chd.12019. Cited in PubMed; PMID 23164196. Read the abstract
Knudson JD, Neish SR, Cabrera AG, Lowry AW, Shamszad P, Morales DL, et al. Prevalence and outcomes of pediatric in-hospital cardiopulmonary resuscitation in the United States: an analysis of the Kids' Inpatient Database*. Crit Care Med. 2012 Nov;40(11):2940-4. doi: 10.1097/CCM.0b013e31825feb3f. Cited in PubMed; PMID 22932398. Read the abstract
Moffett BS, Rossano JW. Use of 4-mg/kg/24-hour empiric aminoglycoside dosing in preoperative neonates with congenital heart disease. Ann Pharmacother. 2012 Sep;46(9):1193-7. doi: 10.1345/aph.1Q792. Epub 2012 Aug 21. Cited in PubMed; PMID 22911340. Read the abstract
Shamszad P, Cabrera AG, Kim JJ, Moffett BS, Graves DE, Heinle JS, et al. Perioperative atrial tachycardia is associated with increased mortality in infants undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2012 Aug;144(2):396-401. doi: 10.1016/j.jtcvs.2012.01.026. Epub 2012 Feb 4. Cited in PubMed; PMID 22306216. Read the abstract
Rossano JW, Kim JJ, Decker JA, Price JF, Zafar F, Graves DE, et al. Prevalence, morbidity, and mortality of heart failure-related hospitalizations in children in the United States: a population-based study. J Card Fail. 2012 Jun;18(6):459-70. doi: 10.1016/j.cardfail.2012.03.001. Epub 2012 Apr 10. Cited in PubMed; PMID 2633303. Read the abstract
Law SP, Kim JJ, Decker JA, Price JF, Cabrera AG, Graves DE, et al. Hospital charges for pediatric heart transplant hospitalizations in the United States from 1997 to 2006. J Heart Lung Transplant. 2012 May;31(5):485-91. doi: 10.1016/j.healun.2011.12.008. Epub 2012 Feb 4. Cited in PubMed; PMID 22306440. Read the abstract
Rossano JW, Mott AR. Does paracetamol prevent apnoea in infants? The current dilemma of evaluation of therapies in the absence of randomized controlled trials. Resuscitation. 2012 Apr;83(4):407-8. doi: 10.1016/j.resuscitation.2012.02.001. Cited in PubMed; PMID 22414346. No abstract available.
Maskatia SA, Decker JA, Spinner JA, Kim JJ, Price JF, Jefferies JL,et al. Restrictive physiology is associated with poor outcomes in children with hypertrophic cardiomyopathy. Restrictive physiology is associated with poor outcomes in children with hypertrophic cardiomyopathy. Pediatr Cardiol. 2012 Jan;33(1):141-9. doi: 10.1007/s00246-011-0106-6. Epub 2011 Sep 4. Cited in PubMed; PMID 21892651. Cited in PubMed; PMID 21892651. Read the abstract
Moffett BS, McDade E, Rossano JW, Dickerson HA, Nelson DP. Enteral potassium supplementation in a pediatric cardiac intensive care unit: evaluation of a practice change. Pediatr Crit Care Med. 2011 Sep;12(5):552-4. doi: 10.1097/PCC.0b013e3182076ab4. Cited in PubMed; 21297518. Read the abstract
Rodriguez FH 3rd, Moodie DS, Parekh DR, Franklin WJ, Morales DL, Zafar F, et al. Am J Cardiol. 2011 Jul 15;108(2):290-3. doi: 10.1016/j.amjcard.2011.03.036. Epub 2011 May 3. Cited in PubMed; PMID 21545985. Read the abstract
Wilmot I, Morales DL, Price JF, Rossano JW, Kim JJ, Decker JA, et al. Effectiveness of mechanical circulatory support in children with acute fulminant and persistent myocarditis. J Card Fail. 2011 Jun;17(6):487-94. doi: 10.1016/j.cardfail.2011.02.008. Epub 2011 Apr 22. Cited in PubMed; PMID 21624737. Read the abstract
Zafar F, Heinle JS, Schecter MG, Rossano JW, Mallory GB Jr., Elidemir O, et al. Two decades of pediatric lung transplantation in the United States: have we improved? J of Thorac Cardiovasc Surg. 2011 Mar;141(3):828-32.e.1. Epub 2011 Jan 20. Cited in PubMed: PMID 21255797. Read the abstract
Scully BB, Zafar F, Schecter MG, Rossano JW, Mallory GB Jr, Heinle JS, et al. Lung retransplantation in children: appropriate when selectively applied. Ann Thorac Surg. 2011 Feb;91(2):574-9. doi: 10.1016/j.athoracsur.2010.09.011. Cited in PubMed; PMID 21256317. Read the abstract
Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010 Oct 7(10):1484-8 Epub 2010 Jun 18. Cited in PubMed: PMID 20601155. Read the abstract
Rossano JW, Morales DL, Zafar F, Denfield SW, Kim JJ, Jefferies JL, et al. Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: an analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg. 2010 Sep; 140(3):694-9, 699.e1-2. Epub 2010 May 27. Cited in PubMed: PMID 20537356. Read the abstract
Moulik M, Breinholt JP, Dreyer WJ, Kearney DL, Price JF, Clunie SK, et al. Viral endomyocardial infection is an independent predictor and potentially treatable risk factor for graft loss and coronary vasculopathy in pediatric cardiac transplant recipients. J Am Coll Cardiology. 2010 Aug 10;58(7):582-92. Cited in PubMed: PMID 20688214. Read the abstract
Breinholt JP, Moulik M, Dreyer WJ, Denfield SW, Kim JJ, Jefferies JL, et al. Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant. 2010 Jul;29(7):739-46. Epub 2010 Apr 24. Cited in PubMed: PMID 20456978. Read the article
Salazar JD, Zafar F, Siddiqui K, Coleman RD, Morales DL, Heinle JS, et al. Fenestration during Fontan palliation: now the exception instead of the rule. J Thoracic Cardiovasc Surg. 2010 Jul;140(1):129-36. Cited in PubMed: PMID 20620378. Read the abstract
Rossano JW, Denfield SW, Kim JJ, Price JF, Jefferies JL, Decker JA, et al. B-type natriuretic peptide levels late after transplant predict graft survival in pediatric heart transplant patients. J Heart Lung Transplant. 2010 Mar;29(3):385-6. Epub 2009 Sept 26. Cited in PubMed: PMID 19782608. Read the abstract
Jefferies JL, Taylor MD, Rossano J, Belmont JW, Craigen WJ. Novel cardiac findings in periventricular nodular heterotopia. Am J Med Genet A. 2010 Jan;152A(1):165-8. Cited in PubMed: PMID 20014127. Read the abstract
Posters and Presentations
Rossano J. Hospitalizations in single ventricle patients in the United States: prevalence and outcomes from 2000 to 2006 [poster presentation]. 61st Annual Scientific Session and Expo of the American College of Cardiology ; 2012 Mar 24-27; Chicago, IL
Rossano J. Pediatric heart transplantation from donors with depressed ventricular function: an analysis of the United Network of Organ Sharing database [oral presentation]. 61st Annual Scientific Session and Expo of the American College of Cardiology ; 2012 Mar 24-27; Chicago, IL
Rossano J. Increasing prevalence and decreasing mortality in pulmonary hypertension related hospitalizations in the United States: an analysis of over 20,000 hospital admissions [oral presentation]. 2011 American Heart Association Scientific Sessions; 2011 Nov 14-16; Orlando, FL.
Rossano J. Increasing prevalence and hospital charges in pediatric heart failure related hospitalizations: a population-based study [oral presentation]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.
Rossano J. Cost of heart failure in children in the united states [poster presentation]. Heart Failure Society of America 14th Annual Scientific Meeting; 2010 Sep 12-15; San Diego, CA.
Rossano J. Plasma cell infiltrates in the myocardium of pediatric heart transplant recipients [oral presentation]. International Society for Heart and Lung Transplantation Scientific Sessions; 2010 Apr 21-24; Chicago, IL.
Rossano J. Pediatric heart failure and transplantation [invited lecture]. The Heart Institute, Cincinnati Children's Hospital; 2010 Feb 24; Cincinnati, OH.
Rossano J. Prevalence and outcome of heart failure hospitalization in children [invited lecture]. Winters Center for Heart Failure Research Seminar, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine; 2001 Oct 15; Houston, TX.
- Editorial and Academic Positions
2010 - present, Editorial Advisory Board, Congenital Heart Disease: Clinical Studies from Fetus to Adulthood
2010, Ad Hoc Reviewer, Pediatric Transplantation
2009 - present, Ad Hoc Reviewer, Congenital Heart Disease
Annals of Thoracic Surgery
Congenital Heart Disease
International Journal of Artificial Organs
American Journal of Cardiology
Journal of Cardiac Failure
Academic and institutional committees
October 2012 - present , NIH, Hospital, and Industry Sponsored Registry for Ventricular Assist Devices
- Chair, Pedimacs Hospital Standards Committee
September 2012, Centers for Disease Control and Prevention, Congenital Heart Disease Experts Meeting
- Expert Panel, Setting Priorities in Congenital Heart Disease Research
July 2012 - present, National Institutes of Health – National Heart, Lung, and Blood Institute, Pediatric Heart Network
- Ancillary and Pilot Studies Committee
2009 - present, American Red Cross Advisory Council on First Aid, Aquatics, Safety, and Preparedness
2009 - present, American Red Cross Advisory Sub-council on Cardiopulmonary Resuscitation
- Editorial and Academic Positions