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Patrick M. Viatour, PharmD, PhD

Assistant Professor of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania


2011, Van Beirs Award
2006-2009, Human Frontier Science Program, Long Term Fellowship
2005-2006, European Molecular Biology Organization, Long Term Fellowship
2004, Leon Fredericq Foundation Grant
1999-2003, Special Grant from the Fonds National de la Recherche Scientifique (PhD Grant)
1998, Docquier Foundation Grant

Original Papers


Garfin P, Min D, Bryson J, Serwold T, Edris B, Blackburn CC, Richie E, Weinberg K, Manley N, Sage J and Viatour P: Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. Journal of Experimental Medicine in press, 2013. Read the abstract

Viatour P: Bridges between Cell Cycle Regulation and Self-Renewal Maintenance. Genes and Cancer in press, 2013. Read the abstract


Viatour P, Elhmer U, Saddic L, Dorrell C, Andersen JB, Lin C, et al. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med. 2011 Sept 26;208(10):1963-76. Read the abstract

Viatour P, Sage J. Newly identified aspects of tumor suppression by RB. Dis Model Mech. 2011 Sept; 4(5): 581–585. Read the article

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, et al. MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res. 2011 May; 21(5):798-810. Read the abstract


Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, et al. G1 arrest and differentiation can occur independently of Rb family function. J Cell Biol. 2010 Nov 15;191(4):809-25. Read the article 

Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, et al. Bcl-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. J Biol Chem. 2010 Aug 13; 285(33):25831-40. Read the abstract

Keutgens A, Shostak K, Close P, Zhang X, Hennuy B, Aussems M, et al. The repressing function of the oncoprotein Bcl-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1. Mol Cell Biol. 2010 Aug;30(16):4006-21. Read the article 

Burkhart DL, Ngai LK, Roake C, Viatour P, Thangavel C, Ho VM, et al. Regulation of Rb transcription in vivo by Rb family members. Mol Cell Biol. 2010 Apr;30(7):1729-45. Read the article


Robert I, Aussems M, Zhang X, Keutgens A, Hennuy B, Viatour P, et al. MMP9 induction by a truncated oncogenic NF-kB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes. Oncogene. 2009 Apr 2;28(13):1626-38. Read the abstract

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