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G. Scott Worthen, MD

Attending Neonatologist

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania


1994, American Society for Clinical Investigation
1986, RJR-Nabisco Research Scholar
1983, American Heart Association Clinician-Scientist


Memberships in professional organizations

International societies

International Endotoxin Society

National societies

American College of Chest Physicians
American Thoracic Society
Western Society for Clinical Investigation
American Thoracic Society

  • Member, Program Committee for Allergy, Immunology, and Inflammation Section

Original Papers


Liu Y, Mei J. Gonzales L, Yang G, Dai N, Wang P, et al. IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro. J Immunol. 2011 Mar 1;186(5):3197-205. Epub Jan 31. Cited in PubMed; PMID 21282514. Read the abstract


Fuentes R, Wang Y, Hirsch J, Wang C, Rauova L, Worthen GS. Infusion of mature megakaryocytes into mice yields functional platelets. J Clin Invest. 2010 Nov 1;120(11):3917-22. doi: 10.1172/JC143326. Epub 2010 Oct 25. Cited in PubMed; PMID 20972336. Read the article

Mei J, Liu Y, Dai N, Favara M, Greene T, Jeyaseelan S, et al. CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Immunity. 2010 Jul 23;3(1):106-17. Cited in PubMed; PMID 20643340. Read the abstract


Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, et al. Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell. 2009 Sep 8;16(3):183-94. Cited in PubMed; PMID 19732719. Read the article 

Cai S, Zemans RL, Young SK, Worthen GS, Jeyaseelan S. Myeloid differentiation protein-2-dependent and -independent neutrophil accumulation during Escherichia coli pneumonia. Am J Respir Cell Mol Biol. 2009 Jun;40(6):701-9. Epub 2008 Nov 6. Read the article

Zemans RL, Briones N, Young SK, Malcolm KC, Refaeli Y, Downey GP, et al. A novel method for long term bone marrow culture and genetic modification of murine neutrophils via retroviral transduction. J Immunol Methods. 1009 Jan 30;340(2):102-15. Epub 2008 Nov 14. Cited in PubMed; PMID 19010330. Read the article



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