CCCR News and Updates

CHOP’s Breakthrough Cancer Immunotherapy Program Receives Generous Grant from the Emily Whitehead Foundation

Published on Apr 17, 2018 in CHOP News

Emily Whitehead, the first pediatric patient to receive CAR T-cell therapy, and her family honor the CHOP team who saved her life with a $250,000 research grant to expand the use of the therapy for relapsed or refractory ALL.

Pediatric Cancers Differ from Adult Cancers, and Need Different Treatment Plans, Say CHOP Experts

Published on Feb 28, 2018 in CHOP News

A new study finds important differences in how cancers develop in children as compared to adults, proving the concept that childhood cancers are not "small adult tumors."

T-cell Therapy Pioneered at CHOP Shows Persistent Benefits in Young Leukemia Patients

Published on Feb 01, 2018 in CHOP News

Updated results from a global clinical trial of the CAR T-cell therapy for ALL reveal that children and young adults continued to show high rates of durable, complete remission of their disease.

Proton Therapy Lowers Treatment Side Effects in Pediatric Head and Neck Cancer Patients

Published on Oct 23, 2017 in CHOP News, Cancer Connections

Pediatric patients with head and neck cancer can be treated with proton beam therapy instead of traditional photon radiation, resulting in similar outcomes.

Biology of Childhood Brain Tumors Offers Clues to Precise Treatments

Published on Oct 19, 2017 in CHOP News, Cancer Connections

Researchers have found key differences among the most common types of pediatric brain tumors that may lead to more effective therapy.

CHOP Scientists Identify Gene Variants that Increase Neuroblastoma Risk

Published on Sep 26, 2017 in CHOP News, Cancer Connections

By identifying common gene variants that raise the risk of an aggressive form of the childhood cancer neuroblastoma, researchers may assist diagnostic efforts.

CHOP Researchers Identify Potential Target in Treating High-risk Childhood Cancers

Published on Sep 11, 2017 in CHOP News, Cancer Connections

Oncology researchers studying high-risk children’s cancers have identified a cell surface protein that may offer an important target for immunotherapy, a treatment that has the potential to zero in on cancer cells without harming healthy cells.

FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University of Pennsylvania and Children’s Hospital of Philadelphia

Published on Aug 30, 2017 in CHOP News, International Update

This is a game changer for the treatment of pediatric patients battling leukemia and a pivotal milestone in this new era of cellular therapies that treat cancer with a patient’s own immune system.

Research on Crucial Cutting Enzyme Maps DNA Damage in Leukemias

Published on Jun 15, 2017 in CHOP News

A DNA-cutting enzyme that regulates gene structure has a broad role in causing certain cancers. This discovery may eventually lead to more precise treatments.

Protein Network Signals Found to Drive Myeloid Leukemias

Published on Jun 14, 2017 in CHOP News

CHOP researchers reveal how mutations in a protein network drive several high-risk leukemias, offering prospects for new therapies.